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Condition

Anxiety Disorders Clinical Trials

Studies of anxiety disorders, matched by condition name and medical subject headings. Start with those open to enrolment.

10,756 registered studies

In numbers

Open to volunteers
2,143
Active
2,487
With results posted
878
All registered
10,756

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 2,143
  • Generalized Anxiety Disorder

    Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms

    • Recruiting
    • Age: 18 to 60 years
    • Surgery or procedure

    This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) as an adjunctive treatment for generalized anxiety disorder (GAD).

    Trial name
    NCT07392645
    Testing
    Electroacupuncture (EA), Medication
    Where
    China
    Volunteers
    123 people, healthy volunteers welcome
    Sponsor
    Lishu Gao
    Can I take part? NCT07392645
  • Dyssynergic Defecation

    Effects of Connective Tissue Massage Plus Biofeedback for Dyssynergic Defecation

    • Recruiting
    • Age: 18 years and older

    The goal of this randomized controlled clinical trial is to evaluate the effects of connective tissue massage (CTM) added to electromyographic biofeedback (EMG-BF) in adults with dyssynergic defecation (DD).

    Trial name
    NCT07890727
    Testing
    Electromyographic Biofeedback (EMG-BF), Connective Tissue Massage (CTM)
    Where
    Turkey (Türkiye)
    Volunteers
    56 people
    Sponsor
    Selcuk University
    Can I take part? NCT07890727
  • Mood Disorders, Anxiety Disorders

    Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

    • Recruiting
    • Age: 18 to 65 years
    • Observational study
    • Medical device

    This study is intended to help develop new MRI imaging techniques for studying mood and anxiety disorders. Researchers believe that depression and anxiety disorders may cause structural and functional changes in the brain.

    Trial name
    NCT00397111
    Testing
    7T Magnetic Resonance Imaging scanner
    Where
    United States
    Volunteers
    390 people, healthy volunteers welcome
    Sponsor
    National Institute of Mental Health (NIMH)
    Can I take part? NCT00397111
  • Anxiety Disorders, Major Depressive Disorder

    Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

    • Recruiting
    • Age: 8 to 65 years
    • Phase 2
    • Lifestyle or therapy programme

    Study Description: This study examines relations between neurocognitive and clinical features of pediatric anxiety disorders. The study uses neuro-cognitive tasks, functional magnetic resonance imaging (fMRI), as well as magneto…

    Trial name
    NCT00018057
    Testing
    Attention Bias Modification Training, Fluoxetine, Cognitive Behavioral Therapy
    Where
    2 sites in United States
    Volunteers
    3,500 people, healthy volunteers welcome
    Sponsor
    National Institute of Mental Health (NIMH)
    Can I take part? NCT00018057
  • Adjustment Disorder, Anxiety Disorder

    Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment

    • Recruiting
    • Age: 18 to 90 years

    This clinical trial tests the safety, tolerability, and effectiveness of a virtual reality intervention to improve psychological symptom burden for cancer patients undergoing treatment.

    Conditions
    Adjustment Disorder, Anxiety Disorder, Depression, Hematopoietic and Lymphoid System Neoplasm
    Trial name
    NCT07221409
    Testing
    Questionnaire Administration, Virtual Reality (VR) Intervention
    Where
    United States
    Volunteers
    24 people
    Sponsor
    Mayo Clinic
    Can I take part? NCT07221409
  • Anxiety Symptoms, Anxiety Disorders

    TOUCHminds: Help-seeking in Adolescents With Anxiety

    • Recruiting
    • Age: 15 to 19 years
    • Lifestyle or therapy programme

    Adolescents frequently experience clinical and subclinical anxiety symptoms, yet many avoid seeking professional help. While universal interventions exist to promote help-seeking, targeted programs for adolescents with elevated…

    Trial name
    TOUCHminds (NCT07366580)
    Testing
    TOUCHminds - Web-Based Intervention
    Where
    Portugal
    Volunteers
    96 people, healthy volunteers welcome
    Sponsor
    Aveiro University
    Can I take part? TOUCHminds
  • Anxiety, Surgery

    Music Interventions During Wide-Awake Hand Surgery

    • Recruiting
    • Age: 18 years and older

    The purpose of this study is to examine if patients have a lower anxiety level during wide awake hand surgery while listening to their choice of music vs standardized relaxation music.

    Trial name
    NCT05472909
    Testing
    Standardized Relaxation Music, Personal Choice of Music
    Where
    United States
    Volunteers
    170 people
    Sponsor
    University of Wisconsin, Madison
    Can I take part? NCT05472909
  • Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm

    Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer

    • Recruiting
    • Age: 18 years and older
    • Surgery or procedure

    This clinical trial tests how well different types of massage therapy works to reduce anxiety during chemotherapy infusions in patients with cancer.

    Trial name
    NCT07184294
    Testing
    Best Practice, Biospecimen Collection, Massage Therapy
    Where
    United States
    Volunteers
    50 people
    Sponsor
    City of Hope Medical Center
    Can I take part? NCT07184294
  • Dyspnea, Sleep Quality

    Visual and Auditory Stimulation in Intensive Care Patients

    • Not yet recruiting
    • Age: 18 to 60 years

    This study is a randomized controlled experimental clinical trial designed to investigate the effects of visual and auditory stimulation on dyspnea severity, sleep quality, and anxiety levels in patients receiving noninvasive…

    Conditions
    Dyspnea, Sleep Quality, Anxiety, Intensive Care Patients
    Trial name
    NCT07895030
    Testing
    The Northern Lights and White Noise
    Volunteers
    44 people, healthy volunteers welcome
    Sponsor
    University of Yalova
    Can I take part? NCT07895030
  • Generalized Anxiety Disorder

    A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder

    • Recruiting
    • Age: 18 years and older
    • Phase 3

    This is a global, phase 3, randomized, double-blind, parallel-group, 3-arm, placebo-controlled, multicenter study designed to compare the efficacy, safety, and tolerability of fixed doses of SEP-363856 (50 and 75 milligrams per…

    Trial name
    NCT07759128
    Testing
    SEP-363856
    Where
    17 sites in United States
    Volunteers
    576 people
    Sponsor
    Otsuka Pharmaceutical Development & Commercialization, Inc.
    Can I take part? NCT07759128

Completed, with results posted

All 790
  • Obsessive-Compulsive Disorder

    Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

    • Completed
    • Age: 21 to 65 years
    • Phase 1
    • Results posted

    This study aims to investigate the effects of oral psilocybin on OCD symptomatology and provide the first evidence of the neural mechanism that may mediate psilocybin's purported therapeutic effects on OCD.

    Trial name
    NCT03356483
    Testing
    Psilocybin (0.25mg/kg), Niacin (250mg)
    Where
    United States
    Volunteers
    28 people
    Sponsor
    Yale University
    Can I take part? NCT03356483
  • Cancer, Quality of Life

    The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer

    • Completed
    • Age: 12 to 24 years
    • Lifestyle or therapy programme
    • Results posted

    Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer

    Conditions
    Cancer, Quality of Life, Anxiety, Depression
    Trial name
    PRISM-AC (NCT03668223)
    Testing
    Promoting Resilience in Stress Management (PRISM)
    Where
    5 sites in United States
    Volunteers
    269 people
    Sponsor
    Dana-Farber Cancer Institute
    Can I take part? PRISM-AC
  • Anxiety, Insomnia

    Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

    • Completed
    • Age: 65 years and older
    • Results posted

    The main purpose of this 12-week study is to see if a new combination of treatments can help older adults reduce benzodiazepine or related medication use.

    Conditions
    Anxiety, Insomnia, Benzodiazepine, Deprescription
    Trial name
    NCT06197243
    Testing
    Acupuncture, Yoga, Deprescribing
    Where
    United States
    Volunteers
    23 people, healthy volunteers welcome
    Sponsor
    Vanderbilt University Medical Center
    Can I take part? NCT06197243
  • Anxiety, Depression

    Factorial Optimization Trial to Test Effects of Coping Intervention Components

    • Completed
    • Age: 9 to 12 years
    • Lifestyle or therapy programme
    • Results posted

    This study will identify components for inclusion in a coping intervention package to reduce mental health problems among children exposed to high interparental conflict after parental separation/divorce.

    Conditions
    Anxiety, Depression, Coping Skills, Emotional Problem
    Trial name
    NCT05822687
    Testing
    Education, Reappraisal Coping, Distraction Coping
    Where
    United States
    Volunteers
    148 people
    Sponsor
    Arizona State University
    Can I take part? NCT05822687
  • Depression, Anxiety

    HIV Engagement and Adolescent Depression Support (HEADS-UP)

    • Completed
    • Age: 13 to 18 years
    • Lifestyle or therapy programme
    • Results posted

    This pilot study will individually randomize 105 adolescents living with HIV 1:1:1 to standard of care, adapted intervention, or enhanced intervention.

    Conditions
    Depression, Anxiety, Adolescent Behavior, HIV Infections
    Trial name
    HEADS-UP (NCT06173544)
    Testing
    Standard of Care (SOC), Adapted Friendship Bench (AFB), Enhanced Friendship Bench (EFB)
    Where
    5 sites in Malawi
    Volunteers
    106 people
    Sponsor
    University of North Carolina, Chapel Hill
    Can I take part? HEADS-UP

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