Condition
Blood Pressure Clinical Trials
Studies of blood pressure, matched by condition name and medical subject headings. Start with those open to enrolment.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 685Unruptured Intracranial Aneurysm, Intracranial Aneurysm Rupture
Prospective Observational Cohort Study for Predicting Unruptured Intracranial Aneurysm Rupture Risk Using Blood Pressure Variability and 3D Structural Evolution
This is a single-center, prospective, longitudinal observational cohort study in adults with unruptured intracranial aneurysms (UIAs) who are managed by conservative observation rather than immediate surgery or endovascular…
- Trial name
- NCT07893574
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Diet, Healthy, HbA1c
MTM2MTG Pilot Ancillary Study
The investigators will conduct an ancillary study of participants in a completed RCT of medically tailored meals to determine whether transitioning these participants to a medically tailored groceries (MTG) program is a feasible…
- Conditions
- Diet, Healthy, HbA1c, Blood Pressure
- Trial name
- MTM2MTG (NCT07620808)
- Testing
- Medically Tailored Groceries
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
Blood Pressure, Sleep Health
The Sleep2BWell Trial
Improving multiple domains of cardiometabolic health (CMH) through contextual behavioral interventions has the potential to substantially reduce persistent chronic disease disparities.
- Conditions
- Blood Pressure, Sleep Health, Diet, Healthy, Physical Activity
- Trial name
- NCT06565104
- Testing
- Multidimensional Sleep Health Sessions, Healthy Diet Sessions, Physical Activity Sessions
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Columbia University
Critical Illness, Shock
Individualised Blood Pressure Targets Versus Standard Care Among Critically Ill Patients With Shock
Aim The aim of the proposed RCT is to determine effectiveness of a strategy, where MAP (mean arterial blood pressure) targets during vasopressor therapy for shock in ICU are individualized based on patients' own pre-illness MAP…
- Trial name
- REACT-SHOCK (NCT05850962)
- Testing
- Individualised MAP target
- Where
- Australia
- Volunteers
- 1,260 people
- Sponsor
- Rakshit Panwar
Intracerebral Hemorrhage
INTERACT4 Expansion - Validation Study
As an investigator-initiated and conducted, multi-centre, open-label, single-arm prospective observational trial, INTERACT4 Expansion aims to evaluate the feasibility of setting up and conducting a trial that uses a point-of-care…
- Trial name
- INTERACT4 Exp (NCT07231315)
- Testing
- LVOne
- Where
- 6 sites in Australia
- Volunteers
- 163 people
- Sponsor
- The George Institute
Poor Sleep Quality, Gut Microbiome
The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) use affects gut microbiome composition, inflammation, and the body's daily temperature and blood pressure…
- Conditions
- Poor Sleep Quality, Gut Microbiome, Gut Health, Inflammation
- Trial name
- NCT07848594
- Testing
- Overnight Active Temperature Regulation: Eight Sleep Pod System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eight Sleep Inc.
Hypertensive Disorder of Pregnancy, Preeclampsia
Blood Pressure Goal in Preterm Preeclampsia
The purpose of this study is to compare latency (prolongation of pregnancy from diagnosis till delivery) in patients with hypertensive disorders of pregnancy (HDP) with severe features < 34 weeks gestational age (GA), undergoing…
- Trial name
- NCT07894705
- Testing
- Treating BP acutely with intravenous or rapid acting oral medications
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Ohio State University
High Blood Sugar, High Blood Pressure
Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study
Bioactive peptides derived from food proteins show potential for improving human health. One of such promising peptides is namely IRW made from egg white hydrolysate and composed of three peptides.
- Conditions
- High Blood Sugar, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT06555393
- Testing
- Egg White Powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hypertension
IMB-Guided Health Education Intervention for Medication Adherence and Blood Pressure Control in Non-adherent Hypertensive Patients
This study will evaluate the effectiveness of an Information-Motivation-Behavioral Skills (IMB) Model-guided health literacy intervention among adults with hypertension who are non-adherent to prescribed antihypertensive…
- Trial name
- NCT07894068
- Testing
- IMB Model-Guided Health Education Intervention, Usual Care
- Where
- 8 sites in Ethiopia
- Volunteers
- 230 people
- Sponsor
- Bahir Dar University
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Completed, with results posted
All 493Hypertension
Exercise and Vascular Function in Postmenopausal Females With Hypertension
The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity.
- Trial name
- NCT05597033
- Testing
- Exercise, Control
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Michigan State University
Obesity, Hypertension
Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans
Experimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms…
- Conditions
- Obesity, Hypertension, Circadian Dysregulation, Salt; Excess
- Trial name
- NCT04021355
- Testing
- Oral sodium supplementation
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Resistant Hypertension
A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension
This is a Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety, tolerability and the effect of 2 mg Baxdrostat vs.
- Trial name
- Bax24 (NCT06168409)
- Testing
- Baxdrostat
- Where
- 102 sites in United States, Argentina and 20 more
- Volunteers
- 218 people
- Sponsor
- AstraZeneca
Uncontrolled Hypertension, Resistant Hypertension
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
This is a Phase III, multicentre, randomised, double-blinded, placebo-controlled, parallel group study to evaluate the safety, tolerability and effect of 1 or 2 mg baxdrostat versus placebo, administered once daily (QD) orally…
- Trial name
- BaxHTN (NCT06034743)
- Testing
- Baxdrostat
- Where
- 263 sites in United States, Argentina and 27 more
- Volunteers
- 796 people
- Sponsor
- AstraZeneca
Blood Pressure
Validation of a Novel Non-invasive Continuous Blood Pressure Monitor in Children Ages 2- 17 Years-old
This is a prospective observational study to investigate if a non-invasive blood pressure monitoring device, the CareTaker Pulse Decomposition Analysis (PDA), can accurately measure blood pressure in children when compared to an…
- Trial name
- NCT04817137
- Testing
- CareTaker PDA Device
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Boston Children's Hospital