Condition
Chronic Kidney Disease Clinical Trials
Studies of chronic kidney disease, matched by condition name and medical subject headings. Start with those open to enrolment.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 732End-stage Renal Disease (ESRD), Kidney Transplantation
Microbiota Changes Related to Outcomes in Kidney Transplantation
Chronic kidney disease affects approximately 10% of the world population. End-stage renal disease (ESRD) is associated with immune dysregulation, chronic inflammation, and alteration of the gut and urinary microbiota.
- Trial name
- MICRO-KT (NCT07893691)
- Testing
- Fecal samples, Urinary sample, Blood samples
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease, Dialysis
The KidneyCARE (Community Access to Research Equity) Study
For chronic kidney disease (CKD), there is a lack of unique and powerful platform for patient engagement, research studies and public health advocacy work.
- Conditions
- Chronic Kidney Disease, Dialysis, Kidney Transplant
- Trial name
- NCT05497518
- Testing
- Observational study - registry
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- Tufts Medical Center
Hairy Cell Leukemia (HCL), Chronic Lymphocytic Leukemia (CLL)
Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
Background: Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients and healthy volunteers.
- Conditions
- Hairy Cell Leukemia (HCL), Chronic Lymphocytic Leukemia (CLL), Non-Hodgkins Lymphoma (NHL), Cutaneous T Cell Lymphoma (CTCL)
- Trial name
- NCT01087333
- Where
- United States
- Volunteers
- 1,263 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Chronic Kidney Disease
Effects of Minimally vs. Ultra-Processed Diets on Potassium (K) Handling in CKD
What is this study about? This clinical trial is designed to learn how potassium from different types of food affects blood potassium levels and overall health in people with chronic kidney disease (CKD, stages 3B-5).
- Trial name
- K-HANDLE CKD (NCT06920914)
- Testing
- Low-potassium, ultra-processed diet, Low-potassium, minimally processed diet, Normal potassium-rich, minimally processed diet
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Gastric Antral Vascular Ectasia, Cirrhosis
Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible bleeding.
- Conditions
- Gastric Antral Vascular Ectasia, Cirrhosis, Chronic Kidney Disease
- Trial name
- GAVE (NCT06306963)
- Testing
- Gastric Emptying Breath Test
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Chronic Insomnia
Shiwei Anshen Granules for Chronic Insomnia
This is a multi-center, randomized, controlled clinical study inlcuding 240 subjects with chronic insomnia. The purpose of this study is to evaluate the efficacy and safety of Shiwei Anshen Granules (an Chinese herbal…
- Trial name
- Shiwei-Anshen (NCT07895329)
- Testing
- Shiwei Anshen granules
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Dongzhimen Hospital, Beijing
Antiphospholipid (aPL)-Positive, Rheumatic Arthritis
MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)
The primary objective of this multicenter observational registry is to characterize the clinical, epidemiological, and biological profiles of individuals of Middle Eastern, North African, and Levantine ancestry, including…
- Conditions
- Antiphospholipid (aPL)-Positive, Rheumatic Arthritis, Celiac Disease, Focal Segmental Glomerulosclerosis (FSGS)
- Trial name
- MERIT (NCT07892651)
- Where
- Jordan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Axiom Bioregistry
Pruritus, Chronic Kidney Diseases
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
Rationale: People with long term kidney disease who are on haemodialysis (a procedure for removing waste products from the blood) commonly develop a condition that makes their skin very itchy.
- Trial name
- NCT06593392
- Testing
- Difelikefalin
- Where
- 18 sites in China, Greece and 5 more
- Volunteers
- 18 people
- Sponsor
- Vifor Fresenius Medical Care Renal Pharma
Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM)
Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.
The goal of this clinical trial is to develop and evaluate a novel diabetes ketoacidosis risk mitigation strategy to support the safe use of sodium-glucose cotransporter-2 inhibitors (SGLT2i) therapy in participants with type 1…
- Conditions
- Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM), Chronic Kidney Disease, Diabetic Ketoacidosis
- Trial name
- SCOUT-CKD (NCT07325201)
- Testing
- Sotagliflozin initiation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- HealthPartners Institute
Completed, with results posted
All 812Chronic Kidney Diseases
Helping Relationships From Significant Others on Healthy Lifestyle and Quality of Life Among Patients With CKD( CKD Lifestyle)
This clinical trial aims to evaluate the effectiveness of a helping relationships intervention program for patients with chronic kidney disease (CKD).
- Trial name
- CKD lifestyle (NCT02076256)
- Testing
- helping relationships
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Chronic Disease, Frail
Functional Exercise and Nutrition Education Program for Older Adults
There is strong evidence that specific types of exercise can improve health and physical function in older adults. While community exercise classes exist, many older adults with chronic conditions may need guidance from…
- Conditions
- Chronic Disease, Frail, Diabetes Mellitus, Cancer
- Trial name
- MoveStrong (NCT04037436)
- Testing
- Strength and Balance Training & Nutrition Education, Usual Care
- Where
- 5 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Waterloo
Complication of Renal Dialysis, End Stage Renal Disease
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatment delivered intraoperatively at the time of surgical creation of an…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS2 (NCT05425056)
- Testing
- Sirolimus
- Where
- 22 sites in United States, United Kingdom
- Volunteers
- 136 people
- Sponsor
- Vascular Therapies, Inc.
CBD, Transplant Complication
Drug-gene-nutraceutical Interactions of Cannabidiol and Tacrolimus
The information learned in these studies will help to inform doctors as to how to appropriately adjust doses of cannabidiol and tacrolimus in order to improve health outcomes and long-term treatment success for transplant…
- Conditions
- CBD, Transplant Complication, Kidney Disease, Chronic
- Trial name
- NCT05490511
- Testing
- Tacrolimus single dose, Epidiolex single dose, Epidiolex steady-state and tacrolimus single dose
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Indiana University
End Stage Renal Disease, Chronic Kidney Diseases
Shared Decision Making in Dialysis
Older patients ≥65 years with chronic kidney disease (CKD) face challenges in decision making about dialysis. These patients report little effort by physicians to elicit treatment preferences, discuss prognoses, or explain the…
- Trial name
- DIAL-SDM (NCT04392440)
- Testing
- DIAL-SDM, usual care
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Rochester