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Condition

Erectile Dysfunction Clinical Trials

Studies of erectile dysfunction, matched by condition name and medical subject headings. Start with those open to enrolment.

715 registered studies

In numbers

Open to volunteers
105
Active
124
All registered
715

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 105
  • Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer

    Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy

    • Recruiting
    • Age: 18 years and older
    • Phase 2
    • Pill or oral medicine
    • Lifestyle or therapy programme

    Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…

    Conditions
    Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
    Trial name
    ROBOPREP (NCT07576335)
    Testing
    Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
    Where
    3 sites in Australia
    Volunteers
    64 people
    Sponsor
    Surgical Outcomes Research Centre (SOuRCe)
    Can I take part? ROBOPREP
  • Peyronie Disease, Erectile Dysfunction

    Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease

    • Recruiting
    • Age: 18 years and older
    • Injection or infusion
    • Medical device

    The purpose of this research is to determine whether or not low-intensity shockwave therapy (LiSWT) with Xiaflex treatment will result in greater improvements to the curvature of the penis.

    Trial name
    NCT06065436
    Testing
    Collagenase Clostridium Histolyticum, Storz Duolith LiSWT
    Where
    United States
    Volunteers
    60 people
    Sponsor
    Mayo Clinic
    Can I take part? NCT06065436
  • Erectile Dysfunction Due to Venous Disorder, Erectile Dysfunction (ED)

    Embolosclerotherapy Versus Deep Dorsal Vein Revascularization in Venogenic Erectile Dysfunction

    • Recruiting
    • Age: 40 to 80 years
    • Surgery or procedure

    Venous leakage is one of the causes of erectile dysfunction and can be managed using different treatment modalities, including surgical ligation and percutaneous embolization.

    Trial name
    venogenic ED (NCT07604194)
    Testing
    Endovascular embolosclerotherapy, Revacularization of deep dorsal vein
    Where
    Egypt
    Volunteers
    60 people
    Sponsor
    Mansoura University Hospital
  • Erectile Dysfunction

    IT Matters: The Erectile Restoration Registry

    • Enrolling by invitation
    • Age: 18 years and older
    • Observational study
    • Medical device

    The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses

    Trial name
    NCT04200937
    Testing
    Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis
    Where
    25 sites in United States, China and 1 more
    Volunteers
    450 people, healthy volunteers welcome
    Sponsor
    Boston Scientific Corporation
    Can I take part? NCT04200937
  • Erectile Dysfunction, Urinary Incontinence

    Male Pelvic Floor Muscle Rehabilitation Exercises

    • Not yet recruiting
    • Age: 18 to 60 years

    Phase I G128 Study Objective The ischiocavernosus (IC) and bulbospongiosus (BS) muscles are vital components of the superficial perineal layer, serving as the foundation for male sexual health and performance.

    Conditions
    Erectile Dysfunction, Urinary Incontinence, Premature Ejaculation
    Trial name
    NCT07451808
    Testing
    Male Pelvic Floor Rehabilitation #1
    Volunteers
    100 people, healthy volunteers welcome
    Sponsor
    Dream Video LLC
  • Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction

    Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial

    • Not yet recruiting
    • Age: 40 to 75 years
    • Injection or infusion

    This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…

    Trial name
    NCT07863388
    Testing
    Autologous Platelet Rich Plasma
    Where
    Denmark
    Volunteers
    100 people
    Sponsor
    Herlev and Gentofte Hospital
  • Erectile Dysfunctions

    The Purpose of This Study is to Evaluate the Efficacy and Safety of W2505.

    • Not yet recruiting
    • Age: 19 years and older
    • Phase 3

    The purpose of this study is to evaluate the efficacy and safety of W2505.

    Trial name
    NCT07859202
    Testing
    W2505, W2505-P1, W2505-R
    Where
    South Korea
    Volunteers
    228 people
    Sponsor
    GL Pharm Tech Corporation
  • Coronary Artery Disease, Erectile Dysfunction

    Pudendal Atherosclerosis by IVUS-NIRS in Men With Coronary Artery Disease

    • Recruiting
    • Age: 18 years and older
    • Medical device
    • Surgery or procedure

    This prospective, single-center, exploratory study will evaluate the association between atherosclerotic and lipid plaque burden in the internal pudendal arteries, assessed by intravascular ultrasound and near-infrared…

    Conditions
    Coronary Artery Disease, Erectile Dysfunction, Atherosclerosis
    Trial name
    PUDENDAL-NIRS (NCT07856199)
    Testing
    Selective Pudendal Angiography, Pudendal IVUS-NIRS Imaging
    Where
    Mexico
    Volunteers
    60 people
    Sponsor
    Hospital Central Militar
  • Erectile Dysfunction

    Shockwave Therapy on Treating Erectile Dysfunction Following Nerve-sparing Radical Prostatectomy.

    • Not yet recruiting
    • Age: 18 to 70 years
    • Injection or infusion
    • Medical device

    This study will investigate whether low-intensity extracorporeal shockwave therapy (LiESWT) can help men recover erectile function after nerve-sparing prostate cancer surgery.

    Trial name
    REVIVE (NCT07819084)
    Testing
    Low-Intensity Extracorporeal Shockwave Therapy, Standard of Care
    Where
    Canada
    Volunteers
    80 people
    Sponsor
    University of Manitoba
    Can I take part? REVIVE
  • Hypogonadism, Male, Secondary Hypogonadism

    AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism

    • Enrolling by invitation
    • Age: 30 to 65 years
    • Pill or oral medicine

    AIM-TEST is a randomized, double-blind, placebo-controlled clinical trial evaluating whether an AI-guided, microbiome-targeted nutritional intervention can increase the body's own testosterone production in men aged 30-65 years…

    Trial name
    AIM-TEST (NCT07761546)
    Testing
    Fixed-Formula Microbiome-Targeted Oral Nutritional Supplement
    Where
    Turkey (Türkiye)
    Volunteers
    112 people
    Sponsor
    Varol TUNALI
    Can I take part? AIM-TEST

Completed, with results posted

All –
  • Erectile Dysfunction

    Shockwave Therapy and Platelet Rich Plasma for the Treatment of Erectile Dysfunction

    • Completed
    • Age: 30 to 80 years
    • Phase 1
    • Injection or infusion
    • Medical device
    • Results posted

    The purpose of this research study is to evaluate whether the combination of Shock Wave Therapy (SWT) with Platelet Rich Plasma (PRP) is synergistic and can reverse the pathology of microvascular Erectile Dysfunction (ED) and…

    Trial name
    COCKTAIL (NCT05048667)
    Testing
    Shock Wave therapy (SWT), Platelet Rich Plasma (PRP)
    Where
    United States
    Volunteers
    59 people
    Sponsor
    University of Miami
    Can I take part? COCKTAIL
  • Erectile Dysfunction

    Radial Shockwave Therapy for Erectile Dysfunction

    • Completed
    • Age: 18 years and older
    • Pill or oral medicine
    • Medical device
    • Results posted

    Objective: To evaluate the efficacy and safety of radial shock waves for the treatment of erectile dysfunction [ED]. Patients and methods: Randomized, double-blind clinical trial.

    Trial name
    NCT03596047
    Testing
    Radial wave therapy
    Where
    Colombia
    Volunteers
    80 people
    Sponsor
    Boston Medical Group
    Can I take part? NCT03596047
  • Erectile Dysfunction Following Radical Prostatectomy

    MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

    • Completed
    • Age: 40 to 70 years
    • Medical device
    • Results posted

    The investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.

    Trial name
    NCT05673005
    Testing
    MED3000 topical gel
    Where
    United States
    Volunteers
    20 people
    Sponsor
    Brigham and Women's Hospital
    Can I take part? NCT05673005
  • Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction

    Safety, Tolerability and Pharmacokinetics (PK) Evaluation of BZ371A, Topically Administered

    • Completed
    • Age: 18 years and older
    • Phase 1
    • Results posted

    The purpose of this study is to evaluate pharmacokinetics, safety and tolerability profile of BZ371A topically administered in healthy patients.

    Conditions
    Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction, Prostate Cancer, Radical Prostatectomy
    Trial name
    NCT05332340
    Testing
    BZ371A
    Where
    Brazil
    Volunteers
    12 people, healthy volunteers welcome
    Sponsor
    Biozeus Biopharmaceutical S.A.
  • Erectile Dysfunction

    Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis

    • Completed
    • Age: 18 years and older
    • Phase 4
    • Results posted

    The purpose of this research is to determine the effects of penile ring block for local anesthesia with liposomal bupivacaine vs ropivacaine mixture in subjects undergoing surgery for Penile Prosthesis Placement.

    Trial name
    ROVEX-IPP (NCT04801368)
    Testing
    Randomization of two local anesthetics.
    Where
    United States
    Volunteers
    20 people, healthy volunteers welcome
    Sponsor
    Mayo Clinic
    Can I take part? ROVEX-IPP

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