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Condition

Fibromyalgia Clinical Trials

Studies of fibromyalgia, matched by condition name and medical subject headings. Start with those open to enrolment.

1,238 registered studies

In numbers

Open to volunteers
205
Active
232
With results posted
144
All registered
1,238

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 205
  • Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy

    Effects of Adding Vagal Neuromodulation to Manual Therapy in Women With Fibromyalgia

    • Not yet recruiting
    • Age: 18 to 65 years
    • Medical device
    • Lifestyle or therapy programme

    The aim of this study is to investigate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) added to manual therapy on pain, autonomic nervous system function, and illness perception in female patients…

    Conditions
    Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy, Chronic Widespread Pain, Autonomic Nervous System Dysfunction
    Trial name
    NCT07894588
    Testing
    Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Manual Therapy Program, Diaphragmatic Breathing and Stretching Exercises
    Where
    Turkey (Türkiye)
    Volunteers
    44 people
    Sponsor
    Hasan Kalyoncu University
    Can I take part? NCT07894588
  • Arthritis, Fibromyalgia

    Wearable Biofeedback Devices for Remote Physiotherapy and Rehabilitation

    • Enrolling by invitation
    • Age: 60 to 80 years

    This study evaluates the effectiveness of wearable biofeedback devices in improving pain, mobility, and rehabilitation outcomes in elderly patients with arthritis and fibromyalgia in Karachi, Pakistan.

    Conditions
    Arthritis, Fibromyalgia, Chronic Pain
    Trial name
    NCT06960330
    Testing
    Wearable Biofeedback + Virtual Physiotherapy, Standard Physiotherapy Exercises
    Where
    Pakistan
    Volunteers
    120 people
    Sponsor
    University of Karachi
    Can I take part? NCT06960330
  • Myofacial Pain, Myofacial Pain Syndrome

    Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome

    • Recruiting
    • Age: 16 to 70 years
    • Injection or infusion

    This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…

    Conditions
    Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
    Trial name
    BIC-LIDO-MPS (NCT07572994)
    Testing
    Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
    Where
    Egypt
    Volunteers
    30 people
    Sponsor
    Cairo University
  • Fibromyalgia (FM)

    Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia

    • Recruiting
    • Age: 18 to 65 years
    • Medical device

    The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia.

    Trial name
    NCT07644221
    Testing
    Primary Motor Cortex Stimulation, Occipital Lobe Stimulation
    Where
    2 sites in United States
    Volunteers
    50 people
    Sponsor
    Pulkit Grover
    Can I take part? NCT07644221
  • Juvenile Idiopathic Arthritis (JIA), Fibromyalgia

    Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain

    • Recruiting
    • Age: 14 to 26 years
    • Observational study

    The purpose of the study is to discover the underlying subtypes of chronic musculoskeletal pain (muscle and joint pain) in youth.

    Conditions
    Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis
    Trial name
    BRIDGE Pain (NCT07602595)
    Testing
    Not applicable- observational study
    Where
    United States
    Volunteers
    600 people
    Sponsor
    Children's Hospital Medical Center, Cincinnati
    Can I take part? BRIDGE Pain
  • Fibromyalgia, Interoception

    The Role of Interoceptive Sensitivity in Central Sensitization Symptom Severity in Fibromyalgia

    • Recruiting
    • Age: 18 to 65 years
    • Observational study

    In fibromyalgia, the increased central sensitization symptom burden can lead to a disruption in the individual's interoception and difficulties in managing symptoms.

    Conditions
    Fibromyalgia, Interoception, Central Sensitization
    Trial name
    NCT07878286
    Testing
    Central Sensitization Inventory, The Multidimensional Assessment of Interoceptive Awareness scale-2, Revised Fibromyalgia Impact Questionnaire
    Where
    Turkey (Türkiye)
    Volunteers
    110 people
    Sponsor
    Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
    Can I take part? NCT07878286
  • ME/CFS, Fibromyalgia (FM)

    Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study

    • Not yet recruiting
    • Age: 18 to 80 years
    • Medical device

    Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.

    Conditions
    ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
    Trial name
    NCT07874217
    Testing
    Cryotherapy
    Where
    United Kingdom
    Volunteers
    40 people, healthy volunteers welcome
    Sponsor
    Oxford Brookes University
    Can I take part? NCT07874217
  • Fibromyalgia

    Open-Label Safety Study of AXS-14 in Subjects With Fibromyalgia

    • Enrolling by invitation
    • Age: 18 years and older
    • Phase 3
    • Pill or oral medicine

    This is a Phase 3, multi-center, 52-week, open-label trial to evaluate the long-term safety and efficacy of AXS-14 in the management of fibromyalgia.

    Trial name
    NCT07637162
    Testing
    AXS-14 (esreboxetine)
    Where
    35 sites in United States
    Volunteers
    300 people
    Sponsor
    Axsome Therapeutics, Inc.
    Can I take part? NCT07637162
  • Fibromyalgia, Fibromyalgia (FM)

    Feasibility and Preliminary Effects of an Asynchronous Microlearning Intervention on Fibromyalgia Knowledge Among Primary Health Care Workers

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    This randomized controlled pilot trial will evaluate the feasibility and preliminary effects of an asynchronous microlearning intervention on fibromyalgia knowledge among Primary Health Care workers.

    Conditions
    Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome
    Trial name
    FIBROK-PILOT (NCT07865767)
    Testing
    Written Educational Material on Fibromyalgia, Asynchronous Microlearning Intervention on Fibromyalgia
    Where
    Chile
    Volunteers
    68 people, healthy volunteers welcome
    Sponsor
    Instituto Neurociencia Del Dolor
  • Fibromyalgia, Fibromyalgia (FM)

    Multisite Transcutaneous Electrical Nerve Stimulation in Fibromyalgia: A Randomized, Double-Blind, Sham-Controlled Crossover Trial Comparing Two Stimulation Modalities

    • Not yet recruiting
    • Age: 18 to 75 years
    • Medical device

    Fibromyalgia is a chronic and multifactorial disorder characterized by widespread musculoskeletal pain, heightened pain sensitivity, fatigue, sleep disturbances, cognitive complaints, and affective symptoms such as anxiety and…

    Conditions
    Fibromyalgia, Fibromyalgia (FM), Fibromyalgia (FM) OR Fibromyalgia Syndrome
    Trial name
    FIBROPULSE (NCT07872631)
    Testing
    EXOPULSE Mollii Suit
    Volunteers
    24 people
    Sponsor
    Institut De La Colonne Vertebrale Et Des Neurosciences
    Can I take part? FIBROPULSE

Completed, with results posted

All –
  • Chronic Low Back Pain, Negative Affectivity

    Treating Negative Affect in Low Back Pain Patients

    • Completed
    • Age: 18 to 75 years
    • Phase 2
    • Results posted

    This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.

    Trial name
    TNA-LBP (NCT04747314)
    Testing
    Antidepressant, Enhanced Fear Avoidance Rehabilitation
    Where
    3 sites in United States
    Volunteers
    308 people
    Sponsor
    Ajay Wasan, MD, Msc
    Can I take part? TNA-LBP
  • Fibromyalgia

    Randomized Controlled Trial of CES for Fibromyalgia

    • Completed
    • Age: 20 to 60 years
    • Medical device
    • Results posted

    Given recent increasing opioid-related deaths and evidence showing against the use of opioids for non-malignant chronic pain, there is growing need for non-narcotic pain management.

    Trial name
    NCT04115033
    Testing
    Alpha-stim
    Where
    United States
    Volunteers
    50 people
    Sponsor
    VA Office of Research and Development
    Can I take part? NCT04115033
  • Vestibulodynia, Temporomandibular Disorder

    Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

    • Completed
    • Age: 18 to 50 years
    • Phase 2
    • Pill or oral medicine
    • Results posted

    Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.

    Conditions
    Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
    Trial name
    NCT03844412
    Testing
    5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
    Where
    2 sites in United States
    Volunteers
    209 people
    Sponsor
    Duke University
    Can I take part? NCT03844412
  • Arthritis, Gout

    Phone-Based Based Walk With Ease Program for Adults With Arthritis

    • Completed
    • Age: 18 years and older
    • Lifestyle or therapy programme
    • Results posted

    The objective of this study is to examine the short-term (6-weeks and 6 months) and long-term (1 year) effects of a phone-based version of Walk With Ease intervention.

    Conditions
    Arthritis, Gout, Fibromyalgia, Rheumatoid Arthritis
    Trial name
    NCT05289544
    Testing
    Phone-Based Walk With Ease
    Where
    United States
    Volunteers
    267 people, healthy volunteers welcome
    Sponsor
    University of South Carolina
  • Fibromyalgia

    Optimized tDCS for Fibromyalgia: Targeting the Endogenous Pain Control System

    • Completed
    • Age: 18 to 65 years
    • Medical device
    • Surgery or procedure
    • Results posted

    This trial aims at understanding the mechanisms of optimized transcranial direct current stimulation (tDCS) (16 tDCS sessions combined with exercise)] on pain control.

    Trial name
    NCT03371225
    Testing
    Active tDCS, Active Exercise
    Where
    United States
    Volunteers
    116 people
    Sponsor
    Spaulding Rehabilitation Hospital
    Can I take part? NCT03371225

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