Condition
Low Back Pain Clinical Trials
Studies of low back pain, matched by condition name and medical subject headings. Start with those open to enrolment.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 512Low Back Pain
Effects of Motor Control Exercises With and Without Pressure Biofeedback in Recurrent Low Back Pain (MCE)
This study aims to compare the effects of Motor Control Exercises (MCE) with and without Pressure Biofeedback-Guided Training in patients with recurrent low back pain.
- Trial name
- yes (NCT07892079)
- Testing
- Motor Control Exercise with Pressure Biofeedback-Guided Training, Motor Control Exercise
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Management and Technology Lahore
Chronic Non-specific Low Back Pain With Lumbar Multifidus Muscle Injury or Dysfunction
The Intervention Effect of Exercise on Lumbar Multifidus Muscle Injuries
This is a single-center, prospective interventional study. The main purpose is to use ultrasound radiomics to analyze changes in multifidus muscle ultrasound imaging features before and after rehabilitation therapy in patients…
- Trial name
- NCT07892846
- Testing
- Lumbar multifidus muscle rehabilitation exercise
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese PLA General Hospital
Low Back Pain, Low Back Pain and Core Muscle
Gamified Home-Based Core Neuromuscular Training for Chronic Low Back Pain
This randomized controlled trial aims to evaluate the effects of gamified home-based core neuromuscular training on pain intensity, functional disability, core muscular endurance, and exercise adherence in women with chronic…
- Trial name
- NCT07890363
- Testing
- Gamified Intervention Group: core neuromuscular exercise program using a digital application with gamification features, Non-Gamified Control Group
- Volunteers
- 60 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Low Back Pain, Low Back Dysfunction
EFFICACY OF ARTIFICIAL INTELLIGENCE DRIVEN PROGRAM VERSUS TRADITIONAL PHYSICAL THERAPY PROGRAM IN PATIENTS WITH LOW BACK DYSFUNCTION
Low back dysfunction is one of the most common musculoskeletal disorders and is associated with pain, disability, and reduced quality of life.
- Trial name
- AI-LBD (NCT07749833)
- Testing
- AI-Driven Rehabilitation Program, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Chronic Low Back Pain
Visual Feedback-Assisted Sensorimotor Training in Chronic Nonspecific Low Back Pain
Chronic nonspecific low back pain is a common musculoskeletal condition that can negatively affect physical function and quality of life.
- Trial name
- VF-SMT (NCT07887789)
- Testing
- Visual Feedback-Assisted Sensorimotor Training, Conventional Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Low Back Pain
Therapeutic Exercise and Education for Low Back Pain
This study will evaluate a new treatment program for patients with ongoing or long-term low back pain who receive care at primary care physiotherapy units.
- Trial name
- NCT07713082
- Testing
- Therapeutic Exercise, Education on the self-management of low back pain, Usual Care
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- University of Valladolid
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Chronic Low Back Pain (Non-specific, Uncomplicated)
Comparison of Abdominal Expansion and Abdominal Drawing-In Training With Manual and Verbal Cueing in Chronic Non-Specific Low Back Pain
This study aims to investigate the interactive effects of two core stability training strategies-abdominal drawing-in manoeuvre (ADIM) and Dynamic Neuromusculoskeletal Stabilization abdominal expansion (DNS-AE)-and two…
- Trial name
- NCT07318454
- Testing
- Abdominal Drawing-In Manoeuvre Training, Dynamic Neuromusculoskeletal Stabilization Abdominal Expansion Training
- Volunteers
- 96 people
- Sponsor
- National Yang Ming Chiao Tung University
Acute Low Back Pain (Low Back Pain for Less Than 3 Months)
Preventing the Transition From Acute to Persistent Disabling Low Back Pain Through Cognitive Functional Therapy
Acute low back pain often resolves spontaneously, but some patients develop persistent pain and disability. The goal of this clinical trial is to determine whether Cognitive Functional Therapy (CFT), compared with usual care, can…
- Trial name
- FIN-BACK (NCT07877454)
- Testing
- Cognitive Functional Therapy (CFT), Usual Care
- Where
- Finland
- Volunteers
- 461 people
- Sponsor
- University of Oulu
Completed, with results posted
All –Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Low Back Pain, Musculoskeletal Pain
Soft Active Back Exosuit to Reduce Workplace Back Pain
The goal of this clinical trial is to determine if a wearable back exosuit can make it safer and easier for workers who bend, lift, and lower objects in an industrial setting.
- Conditions
- Low Back Pain, Musculoskeletal Pain, Low Back Injury
- Trial name
- NCT05802914
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wyss Institute at Harvard University
Low Back Pain
Translation of Robotic Apparel for Alleviating Low Back Pain
This is a NIAMS-sponsored clinical trial being conducted through the NIH Helping to End Addition Long-term (HEAL) Initiative's Back Pain Consortium (BACPAC) Research Program.
- Trial name
- NCT05736393
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston University Charles River Campus
Chronic Low Back Pain, Negative Affectivity
Treating Negative Affect in Low Back Pain Patients
This study will examine how the use of antidepressant, physical therapy, and combination of both affects pain, function, and depression outcomes in chronic low back pain patients.
- Trial name
- TNA-LBP (NCT04747314)
- Testing
- Antidepressant, Enhanced Fear Avoidance Rehabilitation
- Where
- 3 sites in United States
- Volunteers
- 308 people
- Sponsor
- Ajay Wasan, MD, Msc
Lumbar Spine Surgery, Chronic Low-back Pain
Telehealth Mindfulness After Spine Surgery
The goal of this pilot clinical trial is to compare two behavioral interventions for patients who are recovering from lumbar spinal surgery for a degenerative spine condition. The study aims to answer the following questions: 1.
- Conditions
- Lumbar Spine Surgery, Chronic Low-back Pain, Postsurgical Pain
- Trial name
- NCT05698914
- Testing
- Telehealth mindfulness-based intervention (MBI), Telehealth Education
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center