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Condition

Stress Clinical Trials

Studies of stress, matched by condition name and medical subject headings. Start with those open to enrolment.

13,048 registered studies

In numbers

Open to volunteers
2,331
Active
2,748
With results posted
1,355
All registered
13,048

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 2,331
  • Abdominal Pain/ Discomfort, Irritable Bowel Syndrome

    The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain

    • Not yet recruiting
    • Age: 18 to 50 years
    • Lifestyle or therapy programme

    The proposed pilot study aims to assess the underlying mechanisms of the MBI on IBS pain and the feasibility of using novel technology in the outcome measurements.

    Trial name
    NCT06706778
    Testing
    Music intervention
    Where
    United States
    Volunteers
    30 people
    Sponsor
    Yale University
    Can I take part? NCT06706778
  • Burnout, Secondary Trauma

    PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)

    • Enrolling by invitation
    • Age: 18 years and older
    • Lifestyle or therapy programme

    The investigators propose to test the effectiveness of PATH (Peer Advanced Training for total Health) as an educational workforce intervention for improving peer recovery support specialists' (PRSS) overdose prevention (OP)…

    Conditions
    Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder
    Trial name
    NCT07886944
    Testing
    PATH (Peer Advanced Training for total Health)
    Where
    United States
    Volunteers
    200 people
    Sponsor
    Chestnut Health Systems
    Can I take part? NCT07886944
  • Stress Disorders, Post-Traumatic

    Salience Network Informed rTMS for PTSD

    • Not yet recruiting
    • Age: 18 to 60 years
    • Medical device

    The proposed study will test whether magnetic resonance imaging (MRI)-guided transcranial magnetic stimulation (TMS) can reduce posttraumatic stress disorder (PTSD) symptoms in Veterans.

    Trial name
    NCT07886840
    Testing
    Active MRI-Guided intermittent theta burst stimulation (iTBS)
    Where
    United States
    Volunteers
    84 people
    Sponsor
    VA Office of Research and Development
    Can I take part? NCT07886840
  • Pregnancy Early, PTSD

    PTSD Screening in Pregnant Black Women

    • Recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    This study will compare the effectiveness of two active screening interventions in improving post-traumatic stress disorder (PTSD) symptoms, maternal perinatal care utilization, satisfaction utilization of mental healthcare…

    Trial name
    NCT06522022
    Testing
    Culturally Responsive SBIRT for OB, Brief Screening for PTSD
    Where
    2 sites in United States
    Volunteers
    804 people, healthy volunteers welcome
    Sponsor
    Emory University
    Can I take part? NCT06522022
  • Endometriosis, Quality of Life

    Effects of Ashwagandha Supplementation on Quality of Life and Well-Being in Women With Endometriosis

    • Not yet recruiting
    • Age: 18 to 51 years

    The goal of this clinical trial is to learn how ashwagandha, a herbal dietary supplement, affects quality of life in women with endometriosis. Researchers will also assess how well participants tolerate it.

    Conditions
    Endometriosis, Quality of Life, Pain, Perceived Stress
    Trial name
    Ash_End (NCT07898670)
    Testing
    Ashwagandha
    Where
    Austria
    Volunteers
    90 people
    Sponsor
    Medical University of Vienna
    Can I take part? Ash_End
  • Moral Injury

    Mobile-Based Resilience Intervention for Moral Injury, Compassion Fatigue, and Distress in ICU Nurses

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    Critical care nurses are routinely exposed to high acuity, mortality, end-of-life decisions, and long rotating shifts, which can lead to moral injury, compassion fatigue (burnout and secondary traumatic stress), and psychological…

    Trial name
    ICU-RESILIENCE (NCT07896447)
    Testing
    Behavioral
    Where
    Egypt
    Volunteers
    160 people
    Sponsor
    Alexandria University
  • Trauma, Psychological, Traumatic Stress Disorder

    Group Cognitive Processing Therapy for Women Survivors of Gender-Based Violence: Feasibility Study

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    Introduction: Post-traumatic stress disorder (PTSD) is a global health challenge requiring effective, evidence-based interventions, such as Cognitive Processing Therapy (CPT).

    Trial name
    HEALING-TRAUMA (NCT07897903)
    Testing
    Group CPT + TAU (Experimental)
    Volunteers
    10 people
    Sponsor
    Universidad Complutense de Madrid
  • Sleep

    Stress, Coping, and Sleep Health Study

    • Not yet recruiting
    • Age: 18 to 120 years
    • Observational study

    Background: Poor sleep is common among refugee groups worldwide. It can lead to an increased risk of heart disease, diabetes, cancer, and premature death. It can also worsen mental health disorders.

    Trial name
    NCT07566481
    Where
    United States
    Volunteers
    70 people
    Sponsor
    National Institute of Environmental Health Sciences (NIEHS)
    Can I take part? NCT07566481
  • Adrenocortical Carcinoma (ACC), Recurrent Adrenocortical Carcinoma (ACC)

    Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

    • Recruiting
    • Age: 18 to 120 years
    • Phase 1
    • Surgery or procedure

    Background: Adrenocortical carcinoma (ACC) is a rare cancer of the adrenal glands. ACC often returns after tumors are removed with surgery. Less than 35% of people with ACC survive 5 years after diagnosis.

    Conditions
    Adrenocortical Carcinoma (ACC), Recurrent Adrenocortical Carcinoma (ACC), Recurrent Abdominal Adrenocortical Carcinoma (ACC), Carcinoma, Adrenocortical
    Trial name
    NCT06487481
    Testing
    Surgical resection, Preoperative RT
    Where
    United States
    Volunteers
    32 people
    Sponsor
    National Cancer Institute (NCI)
    Can I take part? NCT06487481
  • Benign Prostatic Hyperplasia, Benign Prostatic Obstruction

    Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate

    • Not yet recruiting
    • Age: 45 to 80 years
    • Surgery or procedure

    Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.

    Conditions
    Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence (SUI), Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
    Trial name
    ABPS-EAR-BIPO (NCT07893548)
    Testing
    Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
    Volunteers
    230 people
    Sponsor
    Benha University

Completed, with results posted

All 1,240
  • Mindfulness, Colon Cancer

    Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer

    • Completed
    • Age: 45 to 65 years
    • Lifestyle or therapy programme
    • Results posted

    Many neighborhoods in Chicago experience daily exposure to stressors including economic inopportunity and violent crime in public spaces.

    Conditions
    Mindfulness, Colon Cancer, Females
    Trial name
    MindCRC (NCT06323421)
    Testing
    Mindfulness
    Where
    United States
    Volunteers
    24 people, healthy volunteers welcome
    Sponsor
    University of Illinois at Chicago
    Can I take part? MindCRC
  • Pregnancy, Fetal Monitoring

    Use of In-Home Non-Stress Monitoring Device for Fetal Monitoring: A Nonsignificant Risk (NSR) Device Study

    • Completed
    • Age: 22 years and older
    • Medical device
    • Results posted

    This study evaluates the safety and performance of the PregnaOne System, a non-significant risk (NSR) investigational medical device for in-home fetal monitoring in pregnant women during the third trimester.

    Trial name
    NCT07223996
    Testing
    PregnaOne System
    Where
    3 sites in United States
    Volunteers
    71 people, healthy volunteers welcome
    Sponsor
    Nestmedic Spolka Akcyjna
    Can I take part? NCT07223996
  • Sleep Disturbance, Opioid-use Disorder

    Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder

    • Completed
    • Age: 21 to 65 years
    • Phase 2
    • Results posted

    This study is designed to elucidate the role of the orexin neurotransmitter system in sleep disturbance and circadian rhythms of stress that might in turn influence relapse behaviors in persons on medication-assisted treatments…

    Trial name
    NCT04287062
    Testing
    Suvorexant
    Where
    5 sites in United States
    Volunteers
    249 people
    Sponsor
    Johns Hopkins University
    Can I take part? NCT04287062
  • Stress Disorders, Post-Traumatic, Affect

    Examining Effects of a Therapeutic Focus on Positive Memories on Post-Trauma Health

    • Completed
    • Age: 18 to 65 years
    • Lifestyle or therapy programme
    • Results posted

    Posttraumatic stress disorder (PTSD) has devastating health consequences. Evidence-based PTSD interventions address the substantial burden of PTSD on the health of individuals and societies; however, several individuals receiving…

    Conditions
    Stress Disorders, Post-Traumatic, Affect, Memory
    Trial name
    NCT05523453
    Testing
    Processing of Positive Memories Technique (PPMT), Supportive Counseling (SC)
    Where
    United States
    Volunteers
    70 people
    Sponsor
    University of North Texas, Denton, TX
    Can I take part? NCT05523453
  • Burnout, Compassion Satisfaction

    PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R61 Phase Pilot)

    • Completed
    • Age: 18 years and older
    • Phase 2
    • Lifestyle or therapy programme
    • Results posted

    The investigators propose to develop and test the effectiveness of PATH (Peer Advanced Training for total Health) as an educational workforce intervention for improving peer recovery support specialists' (PRSS) overdose…

    Conditions
    Burnout, Compassion Satisfaction, Secondary Trauma
    Trial name
    NCT07218562
    Testing
    PATH (Peer Advanced Training for total Health)
    Where
    United States
    Volunteers
    18 people
    Sponsor
    Chestnut Health Systems
    Can I take part? NCT07218562

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