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Clinical Trials in Lesotho

Studies with at least one site in Lesotho. Open a trial for its sites in Lesotho, who to contact and who can take part.

42 registered studies

In numbers

Open to volunteers
3
Active
6
With results posted
2
All registered
42

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 3
  • Non-communicable Diseases (NCDs)

    Community-Based Chronic Disease Care in Rural Lesotho

    • Recruiting
    • Age: All ages
    • Observational study

    This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho.

    Trial name
    ComBaCaL (NCT05596773)
    Where
    2 sites in Lesotho, Switzerland
    Volunteers
    17,500 people, healthy volunteers welcome
    Sponsor
    University Hospital, Basel, Switzerland
    Can I take part? ComBaCaL
  • HIV-1-infection

    Ndovu RCT: Investing the Optimal Management of Dolutegravir Resistance

    • Recruiting
    • Age: 3 years and older
    • Phase 3
    • Pill or oral medicine

    This clinical trial will address the gap in published data on the effect of dolutegravir (DTG)-associated drug-resistant mutations on viral suppression among people remaining on DTG-based antiretroviral therapy.

    Trial name
    NCT06747507
    Testing
    Dolutegravir Pill, Darunavir+Ritonavir
    Where
    9 sites in Kenya, Lesotho and 2 more
    Volunteers
    392 people
    Sponsor
    University of Nairobi
    Can I take part? NCT06747507
  • HIV-1-infection

    Investigating the Optimal Management of Dolutegravir Resistance

    • Recruiting
    • Age: 1 year and older
    • Observational study
    • Lifestyle or therapy programme

    The goal of this study is to address the gap in published data on viral suppression among people meeting the criteria for virologic failure on dolutegravir (DTG)-based ART regimens without a change in regimen.

    Trial name
    NCT06762054
    Testing
    Continue DTG-based antiretroviral therapy, Enhanced adherence counselling
    Where
    9 sites in Kenya, Lesotho and 2 more
    Volunteers
    6,600 people
    Sponsor
    University of Nairobi

Completed, with results posted

All –
  • Preconception Care

    Nthabi in Lesotho - Implementation

    • Completed
    • Age: 18 to 28 years
    • Lifestyle or therapy programme
    • Results posted

    This project will determine how well the mobile health (mHealth) Nthabi application is introduced and used at district hospitals in Lesotho.

    Trial name
    NCT04354168
    Testing
    mHealth Application
    Where
    Lesotho
    Volunteers
    160 people, healthy volunteers welcome
    Sponsor
    Boston University
    Can I take part? NCT04354168
  • Tuberculosis, Pediatric

    TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI)

    • Completed
    • Age: Up to 14 years
    • Observational study
    • Results posted

    This evaluation will be conducted in ten countries involved in the Catalyzing Pediatric TB Innovation (CaP-TB) project: Cameroon, Cote D'Ivoire, Democratic Republic of Congo, Kenya, Lesotho, Malawi, Tanzania, Uganda, Zimbabwe and…

    Trial name
    TIPPI (NCT03948698)
    Testing
    Innovative approached to pediatric TB care
    Where
    10 sites in Cameroon, Côte d’Ivoire and 8 more
    Volunteers
    4,159,533 people
    Sponsor
    Elizabeth Glaser Pediatric AIDS Foundation
    Can I take part? TIPPI

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