Drug or intervention
Ibuprofen Clinical Trials
Studies that test Ibuprofen, alone, with other treatments or as the comparison.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 127Fibroadenoma, Breast Fibroadenoma
Management of Breast Fibroadenoma: Comparing Observation, Microwave Ablation, and Surgical Excision
The purpose of this study is to evaluate and compare three different management strategies for benign breast fibroadenoma: conservative management with clinical and radiological follow-up (observation), ultrasound-guided…
- Conditions
- Fibroadenoma, Breast Fibroadenoma, Benign Breast Disease
- Trial name
- NCT07890766
- Testing
- Ultrasound-guided percutaneous microwave ablation, Conventional open surgical excision
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Surgery, Pain, Post Operative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial
This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll.
- Trial name
- CARES for Kids (NCT06671002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 9 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Musculoskeletal Pain
Musculoskeletal Outcomes Using Tylenol/Ibuprofen vs. Oral Steroids in New Injuries
In this pilot study, the investigators aim to compare two short-term pain relief methods administered over the course of 6 days in the setting of acute musculoskeletal (MSK) pain: 1.
- Trial name
- MOTION (NCT07393503)
- Testing
- Methylprednisolone 4Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- State University of New York at Buffalo
Appendectomy, Laparoscopic, Acute Appendicitis
Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based…
- Conditions
- Appendectomy, Laparoscopic, Acute Appendicitis, Pediatric Surgery, ERAS
- Trial name
- NCT07643285
- Testing
- Comprehensive 20-Item Pediatric ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahmet Burak Doğan, MD
Pain, Postoperative Pain
Comparison of the Effectiveness of Midpoint Transverse Process to Pleura (MTP) Block and Erector Spinae Plane (ESP) Block in Video-Assisted Thoracoscopic Surgery (VATS) at RS Ngoerah
This randomized, double-blind controlled trial compares two ultrasound-guided fascial plane blocks, the midpoint transverse process to pleura (MTP) block and the erector spinae plane (ESP) block, for postoperative analgesia in…
- Trial name
- MESA-VATS (NCT07868484)
- Testing
- Midpoint Transverse Process to Pleura (MTP) block, Erector spinae plane (ESP) block
- Where
- Indonesia
- Volunteers
- 51 people
- Sponsor
- Udayana University
Postsurgical Pain Management, Postsurgical Pain, Chronic
An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service
The goal of this clinical trial is to learn whether a pain-management program called a Transitional Pain Service can help prevent long-term pain and reduce opioid needs after surgery in adult surgical patients who may be at…
- Conditions
- Postsurgical Pain Management, Postsurgical Pain, Chronic, Opioid Use After Surgery
- Trial name
- TPS-Select (NCT07296770)
- Testing
- TPS-Select, Pharmacologic Pain Management, Interventional Pain Procedures
- Where
- United States
- Volunteers
- 474 people
- Sponsor
- University of California, San Francisco
Electronic Moxibustion, Low Back Pain
Study on the Effect of Electronic Moxibustion on Non-Specific Low Back Pain in Young Adults
This is an interventional clinical study. A total of 90 subjects aged 18 to 40 years are planned to be recruited. The subjects have low back pain that affects daily work and life, resulting in reduced exercise tolerance or…
- Conditions
- Electronic Moxibustion, Low Back Pain, Muscle Hardness
- Trial name
- NCT07858188
- Testing
- Electronic Moxibustion, ibuprofen or celecoxib analgesics
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Pelvic Organ Prolapse (POP), Postoperative Pain
Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management
The goal of this clinical trial is to determine whether suzetrigine, when added to standardized multimodal postoperative analgesia improves pain control and reduces opioid consumption after apical suspension surgery for pelvic…
- Conditions
- Pelvic Organ Prolapse (POP), Postoperative Pain, Urogynecology
- Trial name
- SUSI (NCT07856654)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aditi Talkad
Nail Diseases
Post-op Analgesia of Nail Unit Procedures
The purpose of this study is to directly compare the efficacy of suzetrigine vs. oxycodone+acetaminophen vs. alternating acetaminophen/ibuprofen in controlling post-operative pain after the following nail unit procedures.
- Trial name
- NCT07820969
- Testing
- Suzetrigine, Oxycodone/Acetaminophen, Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Miami
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Completed, with results posted
All 202Opioid Use
Opioid Analgesic Reduction Study
The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain management, a double-blind, stratified…
- Trial name
- OARS (NCT04452344)
- Testing
- opioid-containing analgesic, two over-the-counter analgesics
- Where
- 5 sites in United States
- Volunteers
- 1,815 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pain Measurement
Comparison Between Dexamethasone and Ibuprofen on Pain Prevention and Control Following Surgical Implant Placement
Background and aim: Postoperative pain is an adverse effect of oral surgeries and may therefore be prevented or minimized. This study compares the efficacy of preemptive ibuprofen and dexamethasone protocols in pain prevention…
- Trial name
- CBDIPPCFSIP (NCT02763059)
- Testing
- Ibuprofen 600 mg, Dexamethasone 4 mg, Acetaminophen 1000 mg
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pain, Postoperative Pain
Efficacy of Different Drugs to Control Post Root Canal Treatment Pain
Root canal therapy will ideally eliminate post-endodontic pain but occasionally analgesics are needed to diminish the pain [Owatz et al 2007].
- Conditions
- Pain, Postoperative Pain, Irreversible Pulpitis
- Trial name
- NSAID (NCT02417337)
- Testing
- Paracetamol, Ibuprofen, Mefenamic Acid
- Where
- Sudan
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Khartoum
Low Back Pain
Acute Low Back Pain. Topical Diclofenac and Oral Ibuprofen.
This is a randomized, double-blind placebo-controlled study comparing two different treatments for acute low back pain: oral ibuprofen and topical diclofenac.
- Trial name
- NCT04611529
- Testing
- Ibuprofen 400 mg, Topical diclofenac
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Montefiore Medical Center
Analgesia
Study of Post-Herniorrhaphy Non-opioid MMA Regimens
This is a Phase 3b, open-label study to assess postoperative opioid use in subjects undergoing unilateral open inguinal herniorrhaphy with intraoperative administration of HTX-011 and a postoperative non-opioid multimodal…
- Trial name
- NCT03907176
- Testing
- HTX-011, Luer lock applicator, Ibuprofen
- Where
- 30 sites in United States
- Volunteers
- 209 people
- Sponsor
- Heron Therapeutics