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Drug or intervention

Transcranial Direct Current Stimulation Clinical Trials

Studies that test Transcranial Direct Current Stimulation, alone, with other treatments or as the comparison.

1,479 registered studies

In numbers

Open to volunteers
313
Active
364
With results posted
202
All registered
1,479

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 313
  • Alcohol Use Disorder, Addiction

    Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

    • Recruiting
    • Age: 18 to 65 years
    • Injection or infusion
    • Medical device

    The overarching goal of this project is to expand the traditional expertise in non-invasive neuromodulation at the University of Minnesota towards developing novel paired-neuromodulation approaches using transcranial direct…

    Trial name
    NCT05062369
    Testing
    TaskFlow Transcranial Electrical Stimulation device, Executive Function Focused Cognitive Training
    Where
    United States
    Volunteers
    100 people
    Sponsor
    University of Minnesota
    Can I take part? NCT05062369
  • Epilepsy

    Lily's Grace Temporal Interference

    • Not yet recruiting
    • Age: 18 to 75 years
    • Medical device

    This study is to evaluate the effectiveness of targeted Transcranial Electrical Stimulation with Temporal Interference (TES-TI) interventions to boost Non-Rapid Eye Movement (NREM) sleep, decrease seizures and promote emotional…

    Trial name
    SLEEP-TIES (NCT07520955)
    Testing
    TES-TI, Structural and Functional MRI
    Where
    United States
    Volunteers
    24 people
    Sponsor
    University of Wisconsin, Madison
    Can I take part? SLEEP-TIES
  • Parkinson Disease, Mild Cognitive Impairment

    Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease

    • Recruiting
    • Age: All ages
    • Medical device

    This cross-over pilot study aims to study the acceptability of two methods of non-invasive brain stimulation for the treatment of Parkinson's disease mild cognitive impairment (PD-MCI) - repetitive transcranial magnetic…

    Trial name
    NESCIO-PD (NCT06399731)
    Testing
    High-frequency (10Hz) rTMS, Anodal tDCS
    Where
    Netherlands
    Volunteers
    20 people
    Sponsor
    Amsterdam UMC
    Can I take part? NESCIO-PD
  • Schizophrenia, Working Memory

    tACS for Working Memory in Schizophrenia

    • Recruiting
    • Age: 18 to 50 years
    • Medical device

    This study is a randomized, single-blind, sham-controlled crossover trial enrolling 30 schizophrenia patients, each receiving one active and one sham tACS session (7-day washout), targeting P3/P4 at individual alpha frequency…

    Trial name
    NCT07701343
    Testing
    transcranial alternating current stimulation
    Where
    China
    Volunteers
    30 people
    Sponsor
    Central South University
    Can I take part? NCT07701343
  • Apathy, Brain Stimulation

    Network-based tDCS for Apathy

    • Not yet recruiting
    • Age: 65 years and older
    • Medical device

    Apathy is one of the most common and undertreated neurobehavioral symptoms in older adults with dementia. It is associated with reduced motivation and engagement in daily activities, and may contribute to faster cognitive and…

    Conditions
    Apathy, Brain Stimulation, Dementia
    Trial name
    NCT07900191
    Testing
    transcranial direct current stimulation
    Volunteers
    20 people
    Sponsor
    Hebrew SeniorLife
    Can I take part? NCT07900191
  • Stuttering, Fluency Disorder

    Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter

    • Recruiting
    • Age: 22 years and older
    • Medical device

    The goal of this study is to find out whether a type of noninvasive brain stimulation can help reduce speech errors, such as repetitions, blocks, and prolongations, in people who stutter.

    Trial name
    NCT07354139
    Testing
    High - Definition Transcranial Direct Current Stimulation
    Where
    United States
    Volunteers
    50 people
    Sponsor
    The University of Texas at Dallas
    Can I take part? NCT07354139
  • Aphasia, Stroke

    Implementing Transcranial Direct Current Stimulation in a Rehabilitation Setting

    • Recruiting
    • Age: 18 years and older
    • Observational study
    • Medical device

    This study looks at whether transcranial Direct Current Stimulation (tDCS) can be effectively implemented in inpatient and outpatient rehabilitation settings during routine speech therapy for people who recently had a stroke and…

    Trial name
    tDCS implement (NCT07535788)
    Testing
    transcranial direct current stimulation (tDCS)
    Where
    United States
    Volunteers
    30 people
    Sponsor
    Casa Colina Hospital and Centers for Healthcare
  • Stroke, Neurogenic Overactive Bladder

    Transcranial Direct Current Stimulation for Neurogenic Overactive Bladder Symptoms Among People With Stroke

    • Not yet recruiting
    • Age: 18 to 80 years
    • Medical device
    • Lifestyle or therapy programme

    Neurogenic overactive bladder (nOAB) is a common and distressing sequela following stroke, significantly impairing quality of life and imposing a substantial financial burden.

    Trial name
    NCT07768137
    Testing
    Active transcranial direct current stimulation (tDCS), Pelvic floor muscle training (PFMT)
    Where
    China
    Volunteers
    60 people
    Sponsor
    The Hong Kong Polytechnic University
    Can I take part? NCT07768137
  • Stroke

    Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments

    • Recruiting
    • Age: 18 to 90 years
    • Medical device

    Significant motor impairments occur in 80% of individuals after moderate to severe stroke and impact the body side to the lesioned hemisphere.

    Trial name
    NCT05479006
    Testing
    Transcranial direct current stimulation (high- definition)
    Where
    United States
    Volunteers
    30 people
    Sponsor
    Carle Foundation Hospital
    Can I take part? NCT05479006
  • Depression and Suicide

    Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation

    • Recruiting
    • Age: 18 years and older
    • Medical device

    The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideation

    Trial name
    tDCS-IDSDEP (NCT06009523)
    Testing
    Transcranial direct current stimulation
    Where
    2 sites in France
    Volunteers
    50 people
    Sponsor
    Centre Hospitalier Henri Laborit
    Can I take part? tDCS-IDSDEP

Completed, with results posted

All 238
  • Working Memory

    Non-Invasive Brain Stimulation to Control Large-Scale Brain Networks

    • Completed
    • Age: 18 years and older
    • Medical device
    • Results posted

    This project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.

    Trial name
    NCT04680481
    Testing
    Transcranial alternating current stimulation
    Where
    United States
    Volunteers
    11 people
    Sponsor
    University of Minnesota
    Can I take part? NCT04680481
  • Acute Lymphoblastic Leukemia

    Neurostimulation In Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)

    • Completed
    • Age: 18 to 39 years
    • Medical device
    • Results posted

    Long-term survivors of ALL are at-risk for neurocognitive impairment, particularly in the area of executive functioning. Relatively limited research has focused on interventions for improving neurocognitive outcomes in long-term…

    Trial name
    NCT04007601
    Testing
    Active tDCS
    Where
    United States
    Volunteers
    127 people
    Sponsor
    St. Jude Children's Research Hospital
    Can I take part? NCT04007601
  • Primary Progressive Aphasia

    Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS

    • Completed
    • Age: 45 to 80 years
    • Phase 2
    • Medical device
    • Lifestyle or therapy programme
    • Results posted

    This is a double-blind, sham-controlled, crossover study in which subjects with the non-fluent/agrammatic and logopenic variants of primary progressive aphasia (naPPA and lvPPA, respectively) will undergo language testing and…

    Trial name
    NCT04046991
    Testing
    high-definition transcranial direct current stimulation, modified constraint-induced language therapy
    Where
    United States
    Volunteers
    76 people
    Sponsor
    University of Pennsylvania
    Can I take part? NCT04046991
  • Aging, Depression

    Cognitive Enhancement in Depression (The COG-D Study)

    • Completed
    • Age: 60 years and older
    • Medical device
    • Lifestyle or therapy programme
    • Results posted

    This study will investigate whether transcranial direct current stimulation (tDCS) enhances the effects of computerized cognitive training in older adults with recurrent depression (2 or more lifetime episodes; either current or…

    Conditions
    Aging, Depression, Cognitive Symptom
    Trial name
    NCT05400512
    Testing
    Cognitive Training, tDCS (active stimulation)
    Where
    United States
    Volunteers
    16 people
    Sponsor
    Vanderbilt University Medical Center
  • Obsessive-Compulsive Disorder

    Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

    • Completed
    • Age: 18 to 60 years
    • Medical device
    • Results posted

    The investigators want to learn more about how human beings learn not to fear and the impact of changing the fear network in the brain using transcranial Direct Current Stimulation (tDCS) in individuals with obsessive compulsive…

    Trial name
    NCT05521074
    Testing
    Active tDCS
    Where
    United States
    Volunteers
    86 people
    Sponsor
    Massachusetts General Hospital

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