Research institution
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Clinical Trials
Studies where Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 56Hepatitis D
Effectiveness and Clinical Outcomes of Long-term Bulevirtide Monotherapy in Patients With HDV-related Compensated Cirrhosis
Retrospective and prospective, pharmacological, multicentre, non-profit observational study. Consecutive patients with HDV-related compensated cirrhosis starting Bulevirtide 2 mg/day from September 2019 to December 2025 will be…
- Trial name
- SAVE-D (NCT06397859)
- Testing
- Bulevirtide
- Where
- Italy
- Volunteers
- 266 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Sexual Health Quality of Life, Infertile Patients
Impact of Infertility on the Sexual Sphere in Couples Undergoing Assisted Reproduction
Fertile and infertile couples attending the Urology Unit and the Assisted Reproductive Technology (ART) Service at our Foundation will be enrolled.
- Conditions
- Sexual Health Quality of Life, Infertile Patients, Assisted Reproduction
- Trial name
- LIFE (NCT07864935)
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Respiratory Distress Syndrome in Premature Infant
REspiratory MEchanics for Delivering Individualised Exogenous Surfactant
This study is an interventional, non-pharmacological, multicentric, randomized, controlled, superiority, non-profit study. Its primary objective is to evaluate if the administration of surfactant based on FOT assessment will…
- Trial name
- REMEDIES (NCT05791331)
- Testing
- Surfactant administration following lung mechanics assessment in addition to clinical assessment, Surfactant administration following clinical assessment
- Where
- Italy
- Volunteers
- 458 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Hepatitis D
Effectiveness and Safety of Bulevirtide (BLV) Therapy in Patients With Chronic Hepatitis Delta (CHD) in Italy (D-SHIELD)
Multicenter pharmacological observational prospective, no-profit, study. This study was designed to get a "real-life" snapshot across several Italian Hepatology centers.
- Trial name
- D-SHIELD (NCT06122285)
- Testing
- Bulevirtide
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Aorta Disease, Aorta, Thoracic Pathologies
Digital Twin and Ml-basEd MOdel of TEVAR Interventions
The study aims to collect clinical data and pseudonymized CT images of patients undergoing TEVAR in order to create an anatomical digital twin capable of simulating procedural outcomes and training machine learning (ML)…
- Trial name
- MEMO (NCT07640828)
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Cerebral Palsy, Early Assessment
Early Detection of Cerebral Palsy Subtype
Early identification of cerebral palsy (CP) has improved with the combined use of the General Movements Assessment (GMA), the Hammersmith Infant Neurological Examination (HINE) and magnetic resonance imaging (MRI).
- Conditions
- Cerebral Palsy, Early Assessment, Early Rehabilitation Intervention
- Trial name
- MILPCI2024 (NCT07916519)
- Testing
- Neurofunctional assessment for early identification of cerebral palsy motor subtypes and functional prognosis
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endometriosis
Dietary Intervention to Improve Fertility in Women With Endometriosis Undergoing IVF
The goal of this randomized controlled trial is to assess whether a 12-week anti-inflammatory diet can improve fertility outcomes in women with endometriosis undergoing In Vitro Fertilization (IVF).
- Trial name
- DANTE (NCT06885125)
- Testing
- anti-inflammatory diet
- Where
- Italy
- Volunteers
- 438 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Acute Myeloid Leukemia
This Study Aims to Improve the Stratification of Patients With Acute Myeloid Leukemia to Enable More Personalized and Effective Treatments, and to Identify and Functionally Validate, at the Single-cell Level, Biomarkers That Can Predict Response to Venetoclax.
The current classification of acute myeloid leukemias (AML) includes more than 20 different diseases, grouped based on their distinctive genomic characteristics, which reflect substantial heterogeneity.
- Trial name
- AMANITA (NCT07874100)
- Testing
- Bulk genotyping of AML samples at diagnosis and relapse, scRNA analysis at diagnosis, scRNAseq and genotyping analysis at day 28 after therapy, spatial transcriptomic analysis at day 0 and 28
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Carotid Artery, Carotid Arteriosclerosis
Predicting High-Risk Carotid Plaque: Integrating radioMics and biomEchanics
Non-pharmacological interventional study for the development of a predictive model aimed at identifying unstable carotid plaques in asymptomatic patients at first diagnosis, with the use of biological material and…
- Trial name
- PRIME (NCT07877480)
- Testing
- Radiomic features analysis
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
NICU Design
NICU Design: Open Space Versus Single Family Room
This prospective, multicenter observational study aims to investigate parents' and healthcare professionals' perceptions of neonatal intensive care unit (NICU) design, comparing Open Space and Single Family Room settings.
- Trial name
- NICUDesign/24 (NCT07877792)
- Where
- 2 sites in Italy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico