Research institution
Huashan Hospital Clinical Trials
Studies where Huashan Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 82Tuberculosis
BRIGHT-Child TB: Short-Course Treatment for Non-Severe Pulmonary Tuberculosis in Children
The goal of this Phase II, multicenter, open-label, randomized controlled trial is to evaluate the efficacy and safety of short-course treatment regimens for children with non-severe, drug-susceptible pulmonary tuberculosis.
- Trial name
- NCT07893444
- Testing
- 4-month FDC-based regimen, 3-month BDCZ regimen, Standard 6-month treatment regimen
- Where
- 13 sites in China
- Volunteers
- 90 people
- Sponsor
- Huashan Hospital
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Hyperphosphatemia, Maintenance Hemodialysis
Tenapanor in Maintenance Hemodialysis Patients
The investigators hypothesize that Tenapanor can improve serum phosphorus control and regulate intestinal metabolism in maintenance hemodialysis patients without increasing the risk of severe gastrointestinal adverse events.
- Trial name
- NCT07882017
- Testing
- Tenapanor
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Huashan Hospital
Stage IVB Oral Cavity Squamous Cell Carcinoma, Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
ImmunoADC Therapy for Induction Conversion in Patients With Stage IVB OSCC/OPSCC
To evaluate the efficacy and safety of Becotatug Vedotin (EGFR-targeted ADC, MRG003) plus Pucotenlimab (PD-1 inhibitor), compared with platinum-based chemotherapy/chemoradiotherapy, as an induction conversion regimen for…
- Trial name
- NCT07844551
- Testing
- Becotatug Vedotin (MRG003), Pucotenlimab, Cisplatin
- Volunteers
- 40 people
- Sponsor
- Huashan Hospital
Hemodialysis, Cognitive Impairment
Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients
In this observational study, the investigators evaluate the influencing factors of cerebrovascular disease and cognition in hemodialysis patients.
- Conditions
- Hemodialysis, Cognitive Impairment, Cerebrovascular Disorders
- Trial name
- NCT04433455
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Huashan Hospital
Amyotrophic Lateral Sclerosis
Efficacy and Safety of Cyclophosphamide in Amyotrophic Lateral Sclerosis
The goal of this clinical trial is to learn whether cyclophosphamide (CTX) combined with standard treatment can slow disease progression in adults with amyotrophic lateral sclerosis (ALS).
- Trial name
- CORTEX-ALS (NCT07834450)
- Testing
- Cyclophosphamide, Riluzole
- Volunteers
- 60 people
- Sponsor
- Huashan Hospital
Oral Cancer, Lymph Node Metastasis
Neck Observation or Elective Neck Dissection in cT1N0M0 OSCC
To evaluate the clinical outcomes of 2-year lymph node metastasis rate, disease-free survival, overall survival, and health-related quality of life in the patients with cT1N0M0 oral squamous cell carcinoma, who receive primary…
- Trial name
- NCT06623266
- Testing
- Neck management
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huashan Hospital
Neuromyelitis Optica Spectrum Disorders (NMOSD)
HANDLE-a Real World Study on Satralizumab in NMOSD
This study is a single-center, retrospective-prospective, non-interventional cohort study to assess the clinical outcomes of Chinese NMOSD patients treated with satralizumab in a real-world patient management model by collecting…
- Trial name
- NCT06829524
- Testing
- Satralizumab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Huashan Hospital
Myelin Oligodendrocyte Glycoprotein (MOG)-Antibody Related Disorders
Evaluation of Two Cell-based Assays for Diagnosing MOG-IgG Associated Disorders
Anti-myelin oligodendrocyte glycoprotein-IgG-associated disorders (MOGAD) is a rare inflammatory autoimmune disease. In addition, since the international MOGAD group proposed live-cell based assays for MOGAD diagnosis in 2023…
- Trial name
- NCT06617962
- Testing
- CBA method of live cells and fixed cells
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Primary Central Nervous System Lymphoma
Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL
This is a three-arm, multicenter, randomized controlled trial. Eligible participants will be randomized to one of three induction regimens via stratified block randomization at a 2:2:1 ratio.
- Trial name
- NCT07185373
- Testing
- Teniposide, Orelabrutinib, MTX
- Where
- 15 sites in China
- Volunteers
- 215 people
- Sponsor
- Huashan Hospital
Completed, with results posted
All 4Idiopathic Parkinson's Disease
The Effect of Pramipexole on Metabolic Network Activity Compared With Levodopa in Early Parkinson's Disease
Levodopa and non-ergot dopaminergic agonists such as pramipexole are both recommended as the first-line symptomatic treatment for early untreated Parkinson's disease (PD), previous clinical trial indicated that initial…
- Trial name
- NCT01470859
- Testing
- pramipexole, Sinemet CR
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huashan Hospital
Postoperative Nausea and Vomiting
Transcutaneous Electrical Acupoint Stimulation of P6 to Prevent Postoperation Nausea and Vomiting
The purpose of this study is to access the effect of TEAS of P6 in the prevention of PONV in women scheduled for gynecologic laparoscopic surgery with general anesthesia.
- Trial name
- TEASP6PPONV (NCT02096835)
- Testing
- Transcutaneous electrical acupoint stimulation, Tropisetron, Dexamethasone
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Huashan Hospital
Glioma, Motor Pathway
Functional Monitoring for Motor Pathway in Brain Tumor Surgery Within Eloquent Area
Resection of brain tumors in eloquent areas involves the risk of postoperative motor deficits. For brain tumors within or adjacent to the eloquent area, maximizing tumor resection while preserving motor function is crucially…
- Trial name
- NCT01351337
- Testing
- diffusion tensor tractography neuronavigation and intraoperative subcortical stimulation
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Huashan Hospital
Brain Neoplasms, Surgery
Cerebral Blood Perfusion Changes After General Anesthesia for Craniotomy
Few studies look into cerebral blood flow (CBF) changes during emergence from general anesthesia for craniotomy. The purpose of this study is to demonstrate CBF changes during emergence from general anesthesia for craniotomy…
- Conditions
- Brain Neoplasms, Surgery, Hyperemia
- Trial name
- NCT01642147
- Testing
- Transcranial Doppler (TCD), jugular venous bulb catheterization, Tumor removal surgery under general anesthesia
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huashan Hospital