Research institution
Huazhong University of Science and Technology Clinical Trials
Studies where Huazhong University of Science and Technology is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 247Stomach Neoplasms
Candonilimab Combined With Fruquintinib and Paclitaxel Albumin-Bound as Second-Line Treatment for Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma
This is a Phase II Study of Candonilimab Combined with Fruquintinib and Paclitaxel Albumin-Bound as Second-Line Treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT07920224
- Testing
- candonilimab combined with fruquintinib and paclitaxel albumin-bound
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sepsis, Circulatory Instability
Ultrasound-Calibrated Pulse Contour Cardiac Output Monitoring: Value and Accuracy in Hemodynamic Care
This is a single-center prospective clinical study in the intensive care unit (ICU). Thirty adult patients with sepsis requiring hemodynamic monitoring and fluid resuscitation will be enrolled.
- Conditions
- Sepsis, Circulatory Instability, Hemodynamic Monitoring
- Trial name
- NCT07920237
- Volunteers
- 30 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Breast Diseases
Evaluation of Scanning and Diagnostic Performance of an Autonomous Dual-Arm Breast Ultrasound Robot
This prospective, multicenter, intraindividual paired study aims to evaluate the autonomous scanning performance of a dual-arm robotic breast ultrasound system and the diagnostic performance of the images it acquires, in…
- Trial name
- NCT07915050
- Testing
- Autonomous Dual-Arm Robotic Breast Ultrasound
- Where
- 4 sites in China
- Volunteers
- 885 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT)
Pulse Wave vs. Saline Contrast EIT for Pulmonary Perfusion in ARDS
Monitoring pulmonary perfusion is crucial in critical care, especially for conditions like ARDS. Electrical Impedance Tomography (EIT) is a valuable, non-invasive tool for real-time bedside monitoring.While well-established for…
- Conditions
- ARDS (Acute Respiratory Distress Syndrome), Electrical Impedance Tomography (EIT), Mechanical Ventilation
- Trial name
- NCT07908368
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Breast Cancer, Ultrasound
Evaluation of the Effect of Using Ultrasound Robots for Breast Cancer Screening
The goal of this clinical trial is to learn if robotic ultrasound screening works as well as or better than traditional sonographer-led screening for detecting breast cancer.
- Trial name
- NCT07331363
- Testing
- Screening of the subjects was conducted using an ultrasonic robot.
- Where
- China
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Malignant Pleural Effusions (Mpe), Lung Cancer (Diagnosis)
Union-LC-MPE Cohort:A Multicenter Cohort Study on Diagnosis and Prognosis of Malignant Pleural Effusion in Lung Cance
Lung cancer is the malignant tumor with the highest incidence and mortality rates in China. Malignant pleural effusion (MPE) is one of its most common complications, affecting approximately 15%-50% of patients with non-small cell…
- Trial name
- NCT07882758
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Sepsis, Critical Illness
Metabolic and Functional Study of γδ T Cells in Critically Ill Patients
This prospective observational cohort study investigates the subset-specific metabolic adaptation and functional remodeling of cytotoxic γδ T cells in critically ill patients with and without sepsis.
- Conditions
- Sepsis, Critical Illness, Immunosuppression, MODS
- Trial name
- NCT07680816
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Breast Cancer, HER2-negative Breast Cancer
Albumin-Bound Paclitaxel (Ⅱ) in Patients With Advanced Breast Cancer
This is a multicenter, prospective, observational real-world study. The study aims to evaluate the efficacy, safety and economic benefits of albumin-bound paclitaxel (Ⅱ) compared with conventional albumin-bound paclitaxel, in…
- Conditions
- Breast Cancer, HER2-negative Breast Cancer, Advanced Breast Cancer
- Trial name
- NCT07899047
- Testing
- Experimental Group, control group
- Where
- China
- Volunteers
- 1,372 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Chronic Insomnia During Perimenopause and Menopause
Clinical Efficacy of Thumbtack Needle for Chronic Insomnia in Perimenopausal and Menopausal Women
A multicenter, randomized, controlled, blinded clinical trial was conducted to evaluate the effects of thumbtack needle on sleep in patients with chronic insomnia during perimenopause and menopause.
- Trial name
- NCT07229976
- Testing
- thumbtack needle
- Where
- 8 sites in China
- Volunteers
- 198 people
- Sponsor
- Huazhong University of Science and Technology
Pulmonary Nodules, Lung Neoplasms
Longitudinal AI-Assisted Management of Indeterminate Pulmonary Nodules
Patients with indeterminate lung nodules often face a choice between continued CT surveillance and invasive investigation. This trial compares management with or without access to an AI report that matches nodules across real…
- Trial name
- NCT07895277
- Testing
- AI-Assisted Longitudinal CT Assessment and Pulmonary Nodule Management
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Completed, with results posted
All 6Critically Ill Patients
Esketamine Induction Intubation in ICU Patients.
Intubation in the intensive care unit (ICU) is usually an emergency. Pathophysiological changes such as shock, respiratory failure, and metabolic acidosis in critically ill patients can significantly increase the incidence of…
- Trial name
- NCT05464979
- Testing
- Esketamine Hydrochloride 28 Mg in 0.2 mL NASAL SOLUTION [Spravato], midazolam, fentanyl
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Diabetes
Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients
Food intake has a great influence on blood glucose of patients with diabetes. This study was designed to determine the glycemic index (GI) of a particular pomelo named Majia pomelo and its effects on postprandial glucose (PPG)…
- Trial name
- NCT02006836
- Testing
- Pomelo, Glucose, Blank
- Where
- China
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Diabetes Mellitus, Type 2
Effectiveness and Safety of Adding Compound Preparation of Pioglitazone and Metformin for Type 2 Diabetic Patients
Secondary failure of sulfonylureas (SUs) can occur in about 30%-40% of type 2 diabetic patients after treatment with SUs for 5 years, although SUs are widely used in type 2 diabetic patients.
- Trial name
- NCT02099838
- Testing
- Pioglitazone and Metformin
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Huazhong University of Science and Technology
Surgery, Individuality
The Realtime Detection for Individual Variation of Analgesic ：A Comparison of Sufentanil vs Fentanyl
Purpose: This study aimed to find a quick and timely way to investigate the individual variation of efficacy of opioid analgesic in Chinese patients undergoing elective surgeries.
- Trial name
- NCT01748071
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Surgery
Impact of CYP3A4*1G Polymorphism on Metabolism of Fentanyl in Chinese Patients Undergoing Lower Abdominal Surgery
Purpose: This study aimed to investigate the impact of CYP3A4*1G genetic polymorphism on metabolism of fentanyl in Chinese patients undergoing lower abdominal surgery.
- Trial name
- NCT01181492
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Huazhong University of Science and Technology