Research institution
Medical University of Vienna Clinical Trials
Studies where Medical University of Vienna is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 139MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease), MetALD
Personalized Dietary Feedback to Reduce Hepatic Steatosis in Patients With MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD) and combined metabolic dysfunction and alcohol-associated liver disease (MetALD) are common chronic liver diseases associated with metabolic dysfunction and an…
- Conditions
- MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease), MetALD, Steatotic Liver Disease
- Trial name
- PERSOMA (NCT07914829)
- Testing
- Personalized Dietary Feedback, Generic Dietary Feedback
- Where
- Austria
- Volunteers
- 174 people
- Sponsor
- Medical University of Vienna
Steatotic Liver Disease
Steatotic Liver Disease in Austria - Prospective Registry With Biobank
Steatotic liver disease (SLD) is the most common chronic liver disease and is associated with an increased risk of liver-related complications, cardiovascular disease, and malignancies.
- Trial name
- SLD-AT (NCT07914582)
- Where
- Austria
- Volunteers
- 20,000 people
- Sponsor
- Medical University of Vienna
Ventilator Lung
I-ASV in Cardiac Surgery
'POStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients II (POSITiVE II) is an investigator-initiated, international, multicenter, parallel, randomized clinical trial in patients after cardiac surgery.
- Trial name
- POSITiVE II (NCT06178510)
- Testing
- INTELLiVENT-ASV.
- Where
- Austria
- Volunteers
- 328 people
- Sponsor
- Medical University of Vienna
Endometriosis, Quality of Life
Effects of Ashwagandha Supplementation on Quality of Life and Well-Being in Women With Endometriosis
The goal of this clinical trial is to learn how ashwagandha, a herbal dietary supplement, affects quality of life in women with endometriosis. Researchers will also assess how well participants tolerate it.
- Conditions
- Endometriosis, Quality of Life, Pain, Perceived Stress
- Trial name
- Ash_End (NCT07898670)
- Testing
- Ashwagandha
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University of Vienna
Blood Donation
Cookies for Platelets
This study aims to evaluate the effects of glucose consumption (in the form of Christmas cookies) on platelet function, as well as the motivation and willingness of healthy platelet donors.The main hypothesis is that consuming…
- Trial name
- c4p (NCT07890467)
- Testing
- Christmas cookies (home-made)
- Where
- Austria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Mitral Regurgitation, ATTR-Cardiomyopathy
Edge-to-edge Mitral Valve Repair in ATTR-CM
No previous study has evaluated the effectiveness of transcatheter edge-to-edge mitral valve repair (TEER) in patients with ATTR-associated cardiomyopathy (ATTR-CM) and significant mitral regurgitation, as this specific patient…
- Conditions
- Mitral Regurgitation, ATTR-Cardiomyopathy, Edge-to-Edge Mitral Valve Repair
- Trial name
- MILLENNIAL (NCT06075823)
- Testing
- TEER, Optimal Medical Therapy
- Where
- 10 sites in Austria, Germany and 1 more
- Volunteers
- 106 people
- Sponsor
- Medical University of Vienna
Medulloblastoma Recurrent, Ependymoma Recurrent
Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors
Patients with with recurrent or progressive medulloblastoma, ependymoma, atypical teratoid rhabdoid tumor (ATRT), and CNS tumors of various histologies have a very poor prognosis whether treated with conventional chemotherapy…
- Conditions
- Medulloblastoma Recurrent, Ependymoma Recurrent, ATRT Recurrent, Rare CNS Tumor Recurrent
- Trial name
- MEMMAT (NCT01356290)
- Testing
- Bevacizumab, Thalidomide, Celecoxib
- Where
- 22 sites in United States, Austria and 6 more
- Volunteers
- 232 people
- Sponsor
- Medical University of Vienna
Graft Function
Intramuscular Injection of Mashed Parathyroid Tissue Into a Forearm During Thyroid Surgery to Prevent Permanent Postoperative Parathyroid Insufficiency (IMIPAT Study)
Parathyroid insufficiency is a common complication in thyroid surgery and occurs in 6.6 to 24%. Up to 4.4% suffer from permanent hypoparathyroidism requiring life-time substitution of calcium and vitamin D in order to maintain a…
- Trial name
- IMIPAT (NCT07516990)
- Testing
- Intramuscular injection of mashed parathyroid tissue into the brachioradial muscle during thyroid surgery
- Where
- 2 sites in Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Carbon Dioxide
Validation of Continuous Transcutaneous Carbon Dioxide Monitoring in VA-ECMO Patients
Carbon dioxide in patients on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is eliminated via respirator as well as via the oxygenator's membrane of the ECMO machine.
- Trial name
- NCT04445909
- Testing
- VA-ECMO
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Rheumatoid Arthritis
MethMax Trial: MAXimising the METHotrexate Therapy Potential in Patients With Active Rheumatoid Arthritis
The MethMax trial is a prospective, international, multicentre, randomised, assessor-blinded, parallel-group, low intervention study.
- Trial name
- MethMax (NCT06649136)
- Testing
- Methotrexate
- Where
- Austria
- Volunteers
- 182 people
- Sponsor
- Medical University of Vienna
Completed, with results posted
All 14Head and Neck Carcinoma
Pembrolizumab Plus Docetaxel for the Treatment of Recurrent or Metastatic Head and Neck Cancer
Squamous cell carcinoma of the head and neck, which accounts for 90% of head and neck cancers, is the tenth most common cancer worldwide with over 650000 new cases per year.
- Trial name
- NCT02718820
- Testing
- Docetaxel, Pembrolizumab
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Medical University of Vienna
Tick Borne Encephalitis
Humoral and Cellular Immunity for TBE Vaccination in Allogeneic HSCT Recipients
Patients undergoing allogeneic blood and marrow transplantation (HSCT) experience a prolonged period of dysfunctional immunity. Systematic reimmunization is necessary at appropriate time intervals following transplantation to…
- Trial name
- NCT01991067
- Testing
- TBE virus vaccine
- Where
- Austria
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Malignant Tumors
Additive Homeopathy in Cancer Patients
The investigators aim to investigate the validity of their previous results in a randomized prospective, placebo-controlled, double-blind, multicenter controlled evaluation of questionnaires in patients with advanced malignant…
- Trial name
- HIC (NCT01509612)
- Testing
- Additive classical homeopathy
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University of Vienna
Healthy Volunteers
Vorapaxar in the Human Endotoxemia Model
Vorapaxar is a recently approved protease activated receptor - 1 (PAR-1) inhibitor. Platelet inhibition may also exert positive results on coagulation activation and may beneficially influence the inflammatory response.
- Trial name
- NCT02875028
- Testing
- Vorapaxar, LPS
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Vaccine Responsiveness in Allergy, Vaccine Responsiveness During Allergy De-sensitization Treatment
TBE (Tick-borne Encephalitis) Vaccination in Allergic Patients
Allergic patients especially those undergoing de-sensitization treatment have an altered immune responsiveness. The investigators aim to find out whether this influences immune responses to primary and booster vaccinations.
- Trial name
- NCT02511535
- Testing
- TBE booster vaccination
- Where
- Austria
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna