Research institution
National University Hospital, Singapore Clinical Trials
Studies where National University Hospital, Singapore is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 76Brain Injuries
Implementation Study on Hospital-to-home Advanced Rehabilitation Technologies (ART)
To study the feasibility of the various model of ART rental service for home use, prescribed and supervised by experienced rehabilitation professionals and supported by tech partners, and its efficacy in improving function in…
- Trial name
- R@H (NCT07904624)
- Testing
- ART
- Where
- 3 sites in Singapore
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
Spontaneous Intracerebral Hemorrhage
PREcision MApping and NEuromodulation After Spontaneous Intracerebral Hemorrhage: The PREMANE Trial
Spontaneous intracerebral haemorrhage (ICH) is a devastating form of stroke accounting for approximately 10-15% of all strokes globally.
- Trial name
- PREMANE (NCT07908264)
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
STOMACH NEOPLASM
Use of Pyrvinium to Reverse Stomach Precancerous Conditions
This study is carried out to find out if a drug called pyrvinium is able to convert pre-cancerous tissue in the stomach back to healthy tissue, to lower the chances of stomach cancer.
- Trial name
- NCT06782048
- Testing
- Pyrvinium, Blood biomarkers analyses, Oesophagogastroduodenoscopy (OGD) and biopsy
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Eczema, Psoriasis
Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology Patients
Skin diseases, despite low mortality, significantly impair quality of life. This randomised controlled trial evaluates the efficacy of a digital toolkit comprising psychotherapeutic strategies in reducing QoL burden in patients…
- Conditions
- Eczema, Psoriasis, Urticaria
- Trial name
- NCT06702293
- Testing
- Digital psychotherapeutic intervention, Healthy365
- Where
- Singapore
- Volunteers
- 690 people
- Sponsor
- National University Hospital, Singapore
Skin Cancer, Skin Cancer Prevention
Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational Program
Skin cancer is a significant public health concern, even in an Asian society like Singapore where it ranks among the top 10 cancers.
- Conditions
- Skin Cancer, Skin Cancer Prevention, Benign Skin Growth
- Trial name
- NCT07247123
- Testing
- Skin Cancer Self-Detection Educational Program with gain-framing, Skin Cancer Self-Detection Educational Program with loss-framing, Wait-list Control
- Where
- Singapore
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Gastric Cancer (GC), Prehabilitation
Multimodal Prehabilitation in Gastric Cancer Patients
This single-arm phase II trial investigates whether a multimodal prehabilitation program can attenuate the postoperative inflammatory response in patients undergoing curative gastric cancer surgery.
- Conditions
- Gastric Cancer (GC), Prehabilitation, Postoperative Inflammation
- Trial name
- PING-P (NCT07839702)
- Testing
- prehabilitation
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- National University Hospital, Singapore
Infraorbital Nerve Injury, Inferior Alveolar Nerve Injury
Nd:YAG Laser Photobiomodulation for Neurosensory Recovery Following Bimaxillary Orthognathic Surgery
This study investigates whether low-energy laser light therapy applied to the skin (photobiomodulation, PBM) can speed up recovery of sensation in the lower lip, chin, and cheek area following jaw surgery (bimaxillary…
- Conditions
- Infraorbital Nerve Injury, Inferior Alveolar Nerve Injury, Neurosensory Disturbance Following Orthognathic Surgery, Photobiomodulation
- Trial name
- NCT07789821
- Testing
- Nd:YAG laser photobiomodulation
- Volunteers
- 36 people
- Sponsor
- National University Hospital, Singapore
This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real World
Community Study to Increase Mammogram Screening Among Overdue Women
Breast cancer is the most common cancer among women in Singapore, and regular mammogram screening can detect breast cancer early when treatment is more effective.
- Trial name
- IMPLEMENT (NCT07832396)
- Testing
- Evidence-based behavioural intervention
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Anxiety and Fear-Related Disorders
Personalized and Accelerated Transcranial Magnetic Stimulation for Treatment-resistant Anxiety Related Disorders
This proposal seeks to carry out an open-label single arm study to examine the neurobehavioral changes induced by personalized, causal network mapping guided accelerated intermittent theta burst stimulation (aiTBS) in patients…
- Trial name
- I2Start (NCT07801391)
- Testing
- Individually Neuronavigated accelerated intermittent theta burst stimulation with MagPro X100
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- National University Hospital, Singapore
Depression Disorder
Maintenance Individualized Neuromodulation and Depression-detection Via Sensors for Early Treatment
This proposal seeks to carry out a prospective, single-arm open label study aimed at sustaining treatment-resistant depression (TRD) response in patients with TRD who had responded to prior individualized resting-state functional…
- Trial name
- MINDSET (NCT07779330)
- Testing
- Individualized resting-state functional connectivity-guided iTBS, Symptom-titrated algorithm-based longitudinal ECT (STABLE) algorithm
- Where
- Singapore
- Volunteers
- 24 people
- Sponsor
- National University Hospital, Singapore
Completed, with results posted
All 3This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women
Trial to Evaluate the Impact of Various Interventions to Increase the Uptake of Surveillance Mammography in Eligible Women in Singapore
Breast cancer is the most common cancer among women in Singapore, with more than 70 women out of every 100,000 being diagnosed each year.
- Trial name
- NCT06733155
- Testing
- Financial intervention, Lottery intervention, Health Messages
- Where
- Singapore
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Stroke
Combined Transcranial Direct Current Stimulation and Motor Imagery-based Robotic Arm Training for Stroke Rehabilitation
Stroke is the most common cause of adult disability. Current treatments for functional loss of the upper extremity post-stroke remain limited in efficacy, particularly for those with moderate to severe impairment.
- Trial name
- NCT01897025
- Testing
- real-tDCS with MI-BCI
- Where
- Singapore
- Volunteers
- 42 people
- Sponsor
- National University Hospital, Singapore
Anaesthesia
Visualization of the Larynx With the Airtraq Laryngoscope and Image Transmission
The Airtraq is a battery powered single use optical laryngoscope with a channel to hold and guide the tracheal tube into the trachea.
- Trial name
- NCT02159768
- Testing
- Airtraq visualization
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National University Hospital, Singapore