Research institution
Ohio State University Clinical Trials
Studies where Ohio State University is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 229Opioid Use Disorder, Alcohol Intoxication
Pain Sensitivity, Alcohol-Induced Analgesia, and Heavy Drinking in Individuals With Opioid Use Disorder
The goal of this clinical trial is to examine whether individuals with co-occurring opioid use disorder and alcohol use (OUD+ALC) experience heightened pain sensitivity, pain-related negative affect, and greater alcohol…
- Conditions
- Opioid Use Disorder, Alcohol Intoxication, Pain
- Trial name
- NCT07894276
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ohio State University
Sexual Assault, Alcohol Intoxication
Examining the Role of Sensitivity to Uncertain Threat and Alcohol Response in Risk for Alcohol Use Disorder Following Sexual Assault in College Women
The goal of this clinical trial is to determine whether women who engage in heavy drinking with a history of sexual assault (SA) victimization show heightened baseline reactivity to uncertain threat (U-threat), whether alcohol…
- Trial name
- NCT07894289
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Ohio State University
Hypertensive Disorder of Pregnancy, Preeclampsia
Blood Pressure Goal in Preterm Preeclampsia
The purpose of this study is to compare latency (prolongation of pregnancy from diagnosis till delivery) in patients with hypertensive disorders of pregnancy (HDP) with severe features < 34 weeks gestational age (GA), undergoing…
- Trial name
- NCT07894705
- Testing
- Treating BP acutely with intravenous or rapid acting oral medications
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Ohio State University
Kidney Stone, Infection
Novel Antimicrobial Solution to Prevent Infections
Ureteroscopy is the most common surgical treatment for kidney stones. Although rare, sepsis after ureteroscopy can be a life-threatening complication, occuring in <3% of patients.
- Conditions
- Kidney Stone, Infection, Infection Associated With Catheter, Sepsis
- Trial name
- NCT07881822
- Testing
- antimicrobial irrigation
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Spinal Cord Injury
Fermented Foods and Bowel Health in SCI
The goal of this clinical trial is to learn whether consuming a high fermented food diet improves bowel function and gut health in adults with chronic spinal cord injury (SCI).
- Trial name
- NCT07640152
- Testing
- fermented foods, Control diet, Sitz Marker Test
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Ohio State University
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
A Navigation Program to Improve Survivorship Support Service Participation Among Non-metastatic Breast Cancer Survivors
This clinical trial studies whether a navigation program improves survivorship support service participation among survivors of breast cancer that has not spread from where it first started (primary site) to other places in the…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT07699991
- Testing
- Best Practice, Patient Navigation, Referral
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Needle Phobia
Lidocaine Patch for Epidural Placement Pain in Laboring Women
Needle phobia can negatively affect the patient experience and may contribute to anxiety during labor procedures. During epidural placement, a standard intradermal lidocaine skin wheal is administered before Tuohy needle…
- Trial name
- NCT07700108
- Testing
- Lidocaine patch 4%, 1% Lidocaine Skin Wheal
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University
Hypertensive Disorders of Pregnancy, Preeclampsia
AtorvaStatin Postpartum and Reduction of Cardiovascular risK
The objective is to conduct a double-blinded randomized controlled trial of atorvastatin vs. placebo among postpartum individuals with hypertensive disorders of pregnancy, to improve cardiovascular risk score postpartum.
- Conditions
- Hypertensive Disorders of Pregnancy, Preeclampsia, Gestational Hypertension
- Trial name
- SPARK (NCT06632379)
- Testing
- Atorvastatin 10 mg
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Recurrent Respiratory Papillomatosis (RRP)
Efficacy of Booster Injection With Gardasil-9 Vaccine on Intersurgical Interval* for Adults With Recurrent Respiratory Papillomatosis*
The investigators propose the study titled "Efficacy of booster injection with Gardasil-9 vaccine on intersurgical interval (ISI) for adults with recurrent respiratory papillomatosis (RRP)".
- Trial name
- *ISI *RRP (NCT07339163)
- Testing
- GARDASIL®9 (Human Papillomavirus 9-valent Vaccine, Recombinant)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Abdominal Aortic Aneurysm
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA).
- Trial name
- AAA-MRE (NCT02387255)
- Testing
- Resoundant Driver System
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Completed, with results posted
All 199Parenting, Adolescent - Emotional Problem
Optimizing Residential Treatment Gains for Adolescents
The goal of this randomized controlled trial is to determine the feasibility, acceptability, and preliminary effects of a web-based parent training augmented with facilitated parent groups.
- Conditions
- Parenting, Adolescent - Emotional Problem, Mental Disorder in Adolescence
- Trial name
- NCT05764369
- Testing
- Parenting Wisely Residential Treatment (PWRT), TAU
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Ohio State University
Physical Activity, Exercise
Mentoring to be Active for Rural Appalachia Children
The innovative MPBA+F begins with peer-to-peer mentoring followed by structured parental/family support for long-term reinforcement of PA behaviors.
- Conditions
- Physical Activity, Exercise, Body Composition
- Trial name
- NCT05758441
- Testing
- Mentoring to be Active plus Family, Tracking Health and Fitness
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Childhood Obesity
Summer Harvest Adventure: A Garden-based Obesity Prevention Program for Children Residing in Low-resource Communities
The objective of this study is to implement and test the efficacy of the "Summer Harvest Adventure," a comprehensive garden-based behavioral, social, and environmental intervention for children (ages 8-11 years) residing in…
- Trial name
- SHA (NCT05367674)
- Testing
- Summer Harvest Adventure, My Summer Plate (MSP)
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy
Natreon Healthy Skin Study - PrimaVie Supplement
This study will demonstrate the ability of the oral supplement, PrimaVie® to improve skin microperfusion, hydration, elasticity and barrier function.
- Trial name
- NCT02762032
- Testing
- PrimaVie Herbal Supplement 125, PrimaVie Herbal Supplement 250
- Where
- 3 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Chronic Venous Leg Ulcers
Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults
The purpose of this study is to test the efficacy of an oral, nutrient intervention containing the bioactive components of fish oil to promote healing of chronic venous leg ulcers (CVLUs) by reducing the chronic inflammation at…
- Trial name
- NCT03576989
- Testing
- EPA+DHA
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Ohio State University