Research institution
University Hospital, Geneva Clinical Trials
Studies where University Hospital, Geneva is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 47Coronary Artery Disease, Diffuse Coronary Artery Disease
Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease
The primary objective of the study is to assess the safety and the efficacy of a hybrid percutaneous coronary intervention (PCI) strategy combining a magnesium-based sirolimus-eluting bioresorbable scaffold (Freesolve, Biotronik…
- Conditions
- Coronary Artery Disease, Diffuse Coronary Artery Disease, Percutaneous Coronary Intervention (PCI)
- Trial name
- BIOHYBRID (NCT06710210)
- Testing
- PCI with a bioresorbable scaffold and drug-coated balloon(s), PCI with drug-eluting stent(s)
- Where
- 4 sites in Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Geneva
Perineal Trauma, Postpartum Pain
RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy
Perineal tears and episiotomies are common after vaginal birth and may cause persistent pain, impaired wound healing, pain during sexual activity, and concerns about genital appearance.
- Conditions
- Perineal Trauma, Postpartum Pain, Episiotomy, Perineal Laceration
- Trial name
- RELIEVE (NCT07727213)
- Testing
- Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva
Wound Healing, Wound Healing Complication
Association Between Female Hormonal Profile and Wound Healing
The goal of this observational study is to assess the relationship between female hormonal status and postoperative wound healing in reduction mammaplasty. The main questions it aims to answer are: 1.
- Conditions
- Wound Healing, Wound Healing Complication, Estradiol
- Trial name
- FEMHEAL (NCT07724145)
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- University Hospital, Geneva
Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD)
Hypnosis on Breathlessness Mastery in Patients With Persistent Dyspnea
Persistent dyspnea is a debilitating symptom, that is common and difficult to treat. This symptom is found in many different diseases including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD)…
- Conditions
- Cancer (With or Without Metastasis), Interstitial Lung Disease (ILD), Chronic Heart Failure (CHF), COPD
- Trial name
- HYPNEA (NCT07173348)
- Testing
- Hypnosis
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Geneva
Diabetes Mellitus, Type 1
Anhydroglucitol in Children With Type 1 Diabetes
The investigators will measure blood levels of 1,5-anhydroglucitol in children with type 1 diabetes and correlate them with parameters related to functional beta-cell mass in diabetic patients.
- Trial name
- NCT05594706
- Testing
- Measurement of blood levels of 1,5-anhydroglucitol
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Breast Reconstruction, Lipofilling
Hyperbaric Oxygen Therapy to Improve Autologous Fat Graft Intake in Irradiated Breast
The goal of this clinical trial is to learn if hyperbaric oxygen therapy (HBOT) enhances fat graft survival in lipofilling procedures in irradiated breast cancer patients.
- Conditions
- Breast Reconstruction, Lipofilling, Hyperbaric Oxygen Therapy
- Trial name
- NCT07140198
- Testing
- Hyperbaric Oxygen Therapy, Control
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University Hospital, Geneva
Heavy Menstrual Bleeding, Bleeding Disorder
Hormonal Management of Heavy Menstrual Bleeding in Adolescents
The goal of this study is to evaluate whether hormonal medications (such as contraceptive pill, patch, injectable progestins and hormonal intra-uterine device) have similar efficacy at managing heavy menstrual bleeding in…
- Trial name
- JAdoRE (NCT06740929)
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- University Hospital, Geneva
Breast Cancer
Ablative SBRT in Elderly BC Patients
Stereotactic body radiotherapy (SBRT) is a modern radiotherapy technique, through which extremely high doses of irradiation are delivered in a very precise manner, within a few fractions.
- Trial name
- EASE (NCT06523894)
- Testing
- SBRT
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University Hospital, Geneva
Morbid Obesity Requiring Bariatric Surgery
Can Pre-operative Lean Mass Predict Weight Loss After Roux-en-Y Gastric Bypass?
The goal of this observational study is to evaluate whether preoperative fat-free mass predicts post-operative weight loss in patients undergoing Roux-En-Y gastric bypass.
- Trial name
- FLAG (NCT07565051)
- Where
- Switzerland
- Volunteers
- 91 people
- Sponsor
- University Hospital, Geneva
Essential Tremor
Transcranial Temporal Interference Stimulation (tTIS) To Modulate Essential Tremor
The goal of this proof-of-concept study is to examine the effects of a relatively new, non-invasive electrical current-based technique, transcranial temporal interference stimulation (tTIS), in patients with Essential Tremor…
- Trial name
- TremorTIS (NCT07531238)
- Testing
- Transcranial temporal interference stimulation, Tremor monitoring through Inertial Measurement Units (IMUs)
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University Hospital, Geneva
Completed, with results posted
All 11Ebolavirus Disease
VSV-ZEBOV Geneva Vaccine Trial
The hemorrhagic fever resulting from Ebola infection is frequently fatal; the current Ebola outbreak, still in its ascendant phase, has a mortality rate over 50%. There is no proven therapy or prevention available at this time.
- Trial name
- VSV-ZEBOV (NCT02287480)
- Testing
- VSV-ZEBOV
- Where
- Switzerland
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Pneumonia
The Place of Imaging and Microbiology in the Diagnosis of Pneumonia in the Elderly
Diagnosis of pneumonia in the elderly is difficult because of the poor sensitivity and specificity of clinical signs as well as images from chest radiography (RT).
- Trial name
- PneumOldCT (NCT02467192)
- Testing
- Low dose CT
- Where
- Switzerland
- Volunteers
- 203 people
- Sponsor
- University Hospital, Geneva
Diabetic Foot
Less Infections for the Diabetic Foot
This is a randomized, unblinded, single-centre study. After eventual surgical debridement (not amputation), patients will be randomized to receive 1 of 2 targeted antibiotic regimens, in the ratio 1:1.
- Trial name
- NCT03615807
- Testing
- Surgical debridement (if needed), Microbiological sampling, Revascularisation (if needed).
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- University Hospital, Geneva
Olecranon Bursitis, Patellar Bursitis
Optimisation of the Treatment of Infectious Bursitis
The study investigates prospectively the cost-savings related to a one-stage bursectomy (debridement, drainage and closure at the same time) versus two-stage bursectomy (debridement, left open and closure at a second time) of…
- Trial name
- NCT01406652
- Testing
- Two-stage bursectomy
- Where
- Switzerland
- Volunteers
- 224 people
- Sponsor
- University Hospital, Geneva
Diabetic Foot Ulcer
Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection
The purpose of this study is to determine whether Garamycin Sponge (Gentamicin-Collagen sponge) in combination with antibiotics is safe and effective in treating moderate and severe diabetic foot infections.
- Trial name
- NCT01951768
- Testing
- Garamycin Sponge (Gentamicin-Collagen sponge), Systemic Antibiotic
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University Hospital, Geneva