Research institution
University Hospital, Strasbourg, France Clinical Trials
Studies where University Hospital, Strasbourg, France is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 256Patients With an Acute Achilles Tendon Rupture, Time From Achilles Tendon Rupture to Surgery of Less Than 2 Weeks
Early Functional Outcomes After Open Versus Percutaneous Repair of Acute Achilles Tendon Ruptures
This study aims to compare early functional outcomes and postoperative complications following open versus percutaneous repair of acute Achilles tendon ruptures in patients younger than 55 years admitted to Hautepierre Hospital.
- Trial name
- STAPO (NCT07914153)
- Testing
- Percutaneous Surgical Repair of Acute Achilles Tendon Rupture, Open Surgical Repair of Acute Achilles Tendon Rupture
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Cognitive Impairment, Chronic Traumatic Encephalopathy (CTE)
A Prospective Study of Cognitive Changes in Retired and Late-Career Professional Soccer Players
Repeated head impacts and concussions may be associated with cognitive difficulties and neurodegenerative changes in athletes. Although this association has been studied primarily in contact sports such as boxing and American…
- Trial name
- TC COG (NCT07910994)
- Volunteers
- 75 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Leukemia, Relapsed or Refractory Pediatric Leukemia
Menin Inhibitors in Pediatric Relapsed or Refractory Acute Leukemia
Acute leukemia is the most common childhood cancer. Despite advances in targeted therapies and immunotherapies, treatment remains challenging for children with relapsed or refractory acute leukemia, particularly those with KMT2A…
- Conditions
- Acute Leukemia, Relapsed or Refractory Pediatric Leukemia, KMT2A-rearranged, NUP98-rearranged, or NPM1-mutated Leukemia, Menin Inhibitor Treatment
- Trial name
- MENIN-PED (NCT07898436)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Strasbourg, France
Incisional Hernia
Patient-Specific Biomechanical Modeling of Incisional Hernias Using Artificial Intelligence and Finite Element Analysis
Incisional hernias are defects in the continuity of the abdominal wall that impair its mechanical function. This retrospective, single-center, non-interventional study aims to develop a patient-specific biomechanical model of the…
- Trial name
- BIO-HERN-IA (NCT07898449)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Strasbourg, France
Perinatal Stroke, Epilepsy
Long-Term Epilepsy Outcomes in Children With a History of Perinatal Stroke
Perinatal stroke is a rare condition affecting approximately 20-40 births per 100,000. It may be ischemic or hemorrhagic and can occur before or around birth, with diagnosis sometimes delayed until motor or cognitive symptoms…
- Conditions
- Perinatal Stroke, Epilepsy, Post-Stroke Epilepsy
- Trial name
- EPI-STROKE (NCT07898397)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Strasbourg, France
Photobiomodulation, Dementia With Lewy Bodies
Evaluating How Red-light Therapy Applied to the Head Affects Symptoms, Daily Life, and Brain Activity in People With Dementia With Lewy Bodies
Dementia with Lewy bodies (DLB) is a neurodegenerative disease diagnosed primarily based on the presence of cognitive decline, which may include difficulties with memory, attention, and more.
- Trial name
- LewyLIGHT (NCT07602296)
- Testing
- LUCIOLE CAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Adult Burkitt Lymphoma, Chemotherapy-Related Toxicity
Toxicity of Intensive First-Line Treatment for Adult Burkitt Lymphoma: A Retrospective Observational Study
Burkitt lymphoma is a rare, highly aggressive B-cell non-Hodgkin lymphoma in adults. Although intensive multi-agent chemotherapy can achieve high complete remission rates, it is associated with substantial toxicity, morbidity…
- Conditions
- Adult Burkitt Lymphoma, Chemotherapy-Related Toxicity, Overall and Progression-Free Survival
- Trial name
- BL-TOX (NCT07895927)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France
Uterine Fibroids, Hysterectomy
Predictors of Success and Failure of v-NOTES Hysterectomy for Large and Very Large Uteri
Uterine fibroids are the most common benign tumors in women of reproductive age and are a major indication for hysterectomy. This retrospective, single-center observational study aims to identify factors associated with the…
- Conditions
- Uterine Fibroids, Hysterectomy, Vaginal Natural Orifice Transluminal Endoscopic Surgery (v-NOTES)
- Trial name
- PRE v-NOTES (NCT07895953)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Myeloid Leukemia, Myeloid Hematological Malignancies
Characterization of CD180 Protein Expression in Myeloid Hematological Malignancies by Flow Cytometry
CD180 is a cell-surface protein recently identified through proteomic analysis as a potential target of interest in myeloid hematological malignancies.
- Conditions
- Acute Myeloid Leukemia, Myeloid Hematological Malignancies, Normal Hematopoietic Stem and Progenitor Cells
- Trial name
- MYEL-CD180 (NCT07895901)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
End-of-life Care, Palliative Care
Prehospital Care of End-of-Life Patients by the Strasbourg Mobile Emergency and Resuscitation Service: A Qualitative Study of Healthcare Professionals' Experiences and Use of a Comfort Care Booklet
Prehospital end-of-life care presents complex clinical, ethical, relational, and organizational challenges for healthcare professionals working in the Strasbourg Mobile Emergency and Resuscitation Service (SMUR).
- Conditions
- End-of-life Care, Palliative Care, Prehospital Emergency Care, Healthcare Professionals' Experiences and Perceptions
- Trial name
- PALLI-SMUR1 (NCT07895940)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Completed, with results posted
All 5Erythema Migrans
Lyme Borreliosis and Early Cutaneous Diagnostic
Test and evaluate a new diagnostic method (SRM-MS/MS: Selected Reaction Monitoring- Mass spectrometry) for Lyme Borreliosis on human skin biopsies. Patients included are those with the early skin manifestation (erythema migrans).
- Trial name
- DIABOLYC (NCT02414789)
- Testing
- Skin biopsies
- Where
- 7 sites in France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Strasbourg, France
Detachment of Glued Mandibular Post-orthodontic Restraints
Comparison of Bonding Failure Rates of Fixed Lingual Mandibular Retainers in a French Sample Aged 11 or Older, Comparing Prior Enamel Sandblasting With Conventional Pumice Polishing
At the completion of orthodontic treatment, the position of the mandibular canines and incisors is being maintained on a routine basis by bonding a multi-braided wire retainer onto their lingual surfaces.
- Trial name
- CONTORTHO (NCT03954145)
- Testing
- Enamel pumicing before bonding the lingual retainer., Enamel sandblasting before bonding the lingual retainer.
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Strasbourg, France
Post-operative Situation
Study of a Prototype Software to Help Surgical Patients Manage Their Pain Medication
The experimental medical device is a prototype software. The device comes in the form of a smartphone with a touch interface. The smartphone used to support the software is a commercial smartphone marked CE.
- Trial name
- MORPHEE 2 (NCT05707247)
- Testing
- software
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Strasbourg, France
Inherited Retinal Disease
Multicenter, Non-interventional Study, Describing Patients With Inherited Retinal Disease (IRD) in France
Genetic diagnostic testing becomes increasingly important for enhancing our understanding of the disease notably the genetics and providing the best care to the patients, and several initiatives seek to gather more data in order…
- Trial name
- EPI-genRET (NCT05122442)
- Testing
- Patients with inherited retinal disease
- Where
- France
- Volunteers
- 998 people
- Sponsor
- University Hospital, Strasbourg, France
MRI Guided Transurethral Ultrasound Ablation, Localized Prostate Cancer
MRI- Guided Transurethral Ultrasound Ablation of Localized Prostate Cancer
Primary purpose : Evaluation of the efficiency and safety of an alternative global prostate treatment in localized prostate cancer.
- Conditions
- MRI Guided Transurethral Ultrasound Ablation, Localized Prostate Cancer, Ablation Therapy
- Trial name
- MRI-TULSAP (NCT03996005)
- Testing
- Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Tissue
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France