Trial phase
Phase not applicable Clinical Trials
Studies of devices, behaviours or procedures that are not drug trials, so FDA phases do not apply.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 43,937Benign Prostatic Hyperplasia
Comparing Rezum and Urolift
This is a randomized controlled trial using a non-inferiority design with the subjects randomized 1:1 to either water vapour thermal treatment (REZUM) arm or prostatic urethral lift (UroLift) arm.
- Trial name
- NCT06820606
- Testing
- Rezum, UroLift
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- Chinese University of Hong Kong
ST-Elevation Myocardial Infarction (STEMI)
Reducing Slow/No-Reflow With Prophylactic High-Dose Intracoronary Adenosine Protocol in ST-Elevation Myocardial Infarction The REFLOW AMI Trial
The REFLOW AMI Trial aims to determine whether prophylactic high-dose intracoronary adenosine reduces slow-flow or no-reflow (SNR) in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous…
- Trial name
- REFLOW AMI (NCT07898696)
- Testing
- Adenosine, Standard Treatment only
- Where
- 2 sites in Pakistan
- Volunteers
- 660 people
- Sponsor
- Prof Muzaffar Ali Zahidi
Bladder Cancer
Role of ERBT Plus Intravesical BCG in Intermediate-Risk or High-Risk NMBC
This is a prospective, multi-centre randomised trial comparing between cTURBT plus 1-year BCG therapy, and ERBT plus 1-year BCG therapy, in patients with intermediate-risk or high-risk NMIBC.
- Trial name
- NCT07724886
- Testing
- Conventional Transurethral Resection of Bladder Tumour, Transurethral En Bloc Resection of Bladder Tumour
- Where
- 2 sites in Hong Kong
- Volunteers
- 732 people
- Sponsor
- Chinese University of Hong Kong
Pulp Necrosis, Apical Periodontitis
Conventional and Nano-Metronidazole Irrigation With/Without Activation in Necrotic Teeth With Apical Periodontitis
This randomized controlled clinical trial evaluates the effect of conventional metronidazole and nano-formulated metronidazole as root canal irrigants, with and without ultrasonic activation, in patients with necrotic…
- Trial name
- NCT07897591
- Testing
- Metronidazole 0.5%, Nano-formulated Metronidazole 0.5%, Sodium Hypochlorite 2.5%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Hemostasis, Surgical Blood Loss
Hemocoll, Avitene, or Bone Wax for Cancellous Bone Bleeding After Single-Ray Amputation
This is a multicentre, prospective, three-arm, parallel-group randomized controlled superiority trial evaluating fibrillar Type-I collagen haemostat (Hemocoll®) FTC, Avitene™ Microfibrillar Collagen Hemostat (MCH), and…
- Conditions
- Hemostasis, Surgical Blood Loss, Amputation Stump, Hemorrhage
- Trial name
- CANHAEM-Ray (NCT07788846)
- Testing
- Hemocoll® Fibrillar type-I collagen haemostat, Bone wax, Avitene™ Microfibrillar Collagen Hemostat
- Where
- 3 sites in India
- Volunteers
- 135 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Depression - Major Depressive Disorder
Understanding the Neural Underpinnings of Risk-Taking Behavior in Psychiatric Disease
The purpose of this study is to understand how the orbitofrontal cortex (OFC), a region at the front of the brain, guides decisions about whether to pursue a possible reward when doing so also carries a risk of loss, and how this…
- Trial name
- NCT07896343
- Testing
- Approach-Avoidance Decision-Making Task
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Anxiety Symptoms, Anxiety Disorders
TOUCHminds: Help-seeking in Adolescents With Anxiety
Adolescents frequently experience clinical and subclinical anxiety symptoms, yet many avoid seeking professional help. While universal interventions exist to promote help-seeking, targeted programs for adolescents with elevated…
- Trial name
- TOUCHminds (NCT07366580)
- Testing
- TOUCHminds - Web-Based Intervention
- Where
- Portugal
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Stellate Ganglion Block, Prolonged Disorders of Consciousness
Stellate Ganglion Block on Postoperative Sleep Status in Patients With Prolonged Disorders of Consciousness
This is a prospective, single-centre, single-arm, self-controlled, exploratory pilot study. The goal of this clinical trial is to learn about the effect of preoperative administration of stellate ganglion block on postoperative…
- Conditions
- Stellate Ganglion Block, Prolonged Disorders of Consciousness, Sleep
- Trial name
- NCT07274683
- Testing
- stellate ganglion block with 0.5% ropivacaine
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Beijing Tiantan Hospital
Hernia, Ventral, Hernia, Hiatal
GORE® ENFORM Biomaterial Product Study
A prospective, retrospective, non-randomized, multicenter study with two independent hernia study cohorts (Ventral / Incisional Hernia Repair and Diaphragmatic / Hiatal Hernia Repair).
- Conditions
- Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
- Trial name
- ENF 18-06 (NCT04718168)
- Testing
- Gore ENFORM Biomaterial (Preperitoneal), Gore ENFORM Biomaterial (Intraperitoneal)
- Where
- 9 sites in United States
- Volunteers
- 245 people
- Sponsor
- W.L.Gore & Associates
Abdominal Pain/ Discomfort, Irritable Bowel Syndrome
The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain
The proposed pilot study aims to assess the underlying mechanisms of the MBI on IBS pain and the feasibility of using novel technology in the outcome measurements.
- Trial name
- NCT06706778
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Completed, with results posted
All 20,296Intubation, Cardiovascular Surgical Procedure
Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula
The iCAN trial is a pragmatic randomized controlled trial that aims to test the hypothesis that HFNC versus usual care oxygenation strategies applied immediately after initial extubation after cardiac surgery decreases the…
- Trial name
- NCT04782817
- Testing
- Recommendation for high flow nasal cannula oxygen therapy order set, Provider choice usual care order set
- Where
- United States
- Volunteers
- 3,568 people
- Sponsor
- Vanderbilt University Medical Center
Prostate Cancer
Rectal Spacer for Prostate Cancer Radiation Image Guidance
The purpose of the study is to determine if a radiopaque hydrogel rectal spacer, SpaceOAR Vue®, can be used in place of fiducial markers when aligning patients for radiotherapy.
- Trial name
- NCT05650021
- Testing
- SpaceOAR Vue
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Milton S. Hershey Medical Center
Mindfulness, Colon Cancer
Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer
Many neighborhoods in Chicago experience daily exposure to stressors including economic inopportunity and violent crime in public spaces.
- Conditions
- Mindfulness, Colon Cancer, Females
- Trial name
- MindCRC (NCT06323421)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Hypertension
A Study of Cardiovascular Disparities in the Greater Mankato Somali Community to Prevent Hypertension
The purpose of this research is to develop ways to reduce hypertension-management-related disparities in the Greater Mankato Area Somali population.
- Trial name
- NCT05873153
- Testing
- Health Education, Home Blood Pressure Monitor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Mild Depressive Disorder Comorbid With Anxiety Disorder
A Clinical Study Evaluating the Efficacy and Safety of CreNeuroS CNS Herbal Nutrition Capsules for Participants With Mild Depressive Disorder Comorbid With Anxiety Disorder
The incidence of Mild Depressive Disorder Comorbid With Anxiety Disorder is dramatically increasing. dietary supplements may show better efficiency and less side effect.Here investigators intend to assess Efficacy and Safety of…
- Trial name
- NCT07295444
- Testing
- A Clinical Study Evaluating the Efficacy and Safety of CreNeuroS CNS Herbal Nutrition Capsules for Participants With Mild Depressive Disorder Comorbid With Anxiety Disorder
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Nanchang University