Specialty
Oncology clinical trials
Trials of treatments, screening and supportive care for solid tumours and blood cancers.
About oncology research
Cancer studies make up the largest share of the registry. Many are early-phase studies of targeted therapies and immunotherapies; others compare established treatment combinations, test screening approaches or look at quality of life during treatment.
Research areas
Open trials in each area. Counts come from the latest copy of the registry.
Recently updated open trials
Studies looking for volunteers, most recently updated by their sponsors first.
Recurrent Respiratory Papillomatosis (RRP), Juvenile-onset Recurrent Respiratory Papillomatosis
Zopapogene Imadenovec for the Treatment of Recurrent Respiratory Papillomatosis in Children
Recurrent respiratory papillomatosis (RRP) is a rare disease in which wart-like growths caused by human papillomavirus (HPV) types 6 or 11 form in the airway.
- Conditions
- Recurrent Respiratory Papillomatosis (RRP), Juvenile-onset Recurrent Respiratory Papillomatosis, Papillomavirus Infections
- Trial name
- NCT07901738
- Testing
- Zopapogene imadenovec-drba
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Precigen, Inc
Recurrent Glioblastoma
A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma
This multi-site Phase II study will enroll adults with histologically confirmed diagnosis of World Health Organization (WHO) Grade IV glioblastoma (GBM), isocitrate dehydrogenase (IDH)-wildtype consistent with WHO central nervous…
- Trial name
- NCT07297212
- Testing
- Pumitamig, Bevacizumab, Temozolomide
- Where
- 6 sites in China
- Volunteers
- 75 people
- Sponsor
- BioNTech SE
Colorectal Neoplasms, Colorectal Cancer (Diagnosis)
MRD Monitoring in Colorectal Cancer Using ctDNA
This clinical study evaluates the use of free circulating tumor DNA (ctDNA) analysis from peripheral blood, known as liquid biopsy.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer (Diagnosis), Minimal Residual Disease
- Trial name
- RezidRAS (NCT07895459)
- Testing
- Blood draw for ctDNA analysis
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Masaryk Memorial Cancer Institute
Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H)
Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Introduction: Major abdominal surgery encompasses a broad range of surgical procedures in heterogeneous patient populations.Management of postoperative pain has received keen attention in recent years with considerable concurrent…
- Conditions
- Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H), Colectomy Left/Right/Total Under Laparotomy, Hepatectomy
- Trial name
- NCT07901582
- Testing
- Epidural administered opioid
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens
Leukemia, Myeloma
HEME Home Transfusion Program
This research study is evaluating whether a new care delivery program that provides access to home blood transfusions in hospice (i.e, HEME-Hospice) compared to regular standard of care improves quality of life, mood, and…
- Conditions
- Leukemia, Myeloma, Myelodysplastic Syndromes, Hematologic Malignancy
- Trial name
- NCT06487247
- Testing
- HEME-Hospice Program
- Where
- 2 sites in United States
- Volunteers
- 700 people
- Sponsor
- Dana-Farber Cancer Institute
Urothelial Carcinoma of the Renal Pelvis and Ureter, Neoadjuvant Therapy
Neoadjuvant Disitamab Vedotin, Toripalimab, and Radiotherapy for High-risk UTUC ( LUXUS07.1 )
This is an open-label, single-arm, single-cohort, prospective clinical study evaluating neoadjuvant antibody-drug conjugate therapy combined with immunotherapy and sequential radiotherapy followed by radical surgery in patients…
- Trial name
- LUXUS0701 (NCT07720921)
- Testing
- Neoadjuvant radiotherapy, ADC + PD1 monoclonal antibody
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University First Hospital
Squamous Non-small-cell Lung Cancer, Head and Neck Squamous Cell Carcinoma
A Study to Investigate ALE.P02 as a Monotherapy or in Combination With Pembrolizumab in Adult Patients With Selected CLDN1+ Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, preliminary anti-tumor activity, and to determine the recommended Phase II dose (RP2D) of the ALE.P02 as a monotherapy or in…
- Conditions
- Squamous Non-small-cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Cervical Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma
- Trial name
- NCT06747585
- Testing
- ALE.P02, Pembrolizumab
- Where
- 41 sites in United States, France and 6 more
- Volunteers
- 235 people
- Sponsor
- Alentis Therapeutics AG
Hereditary Cancer Syndromes
Feasibility Study of a Chatbot AI-Driven Preliminary Screening System for Hereditary Cancer Syndromes
This study aims to assess the feasibility of implementing an AI-based hereditary cancer preliminary screening system that has already been developed.
- Trial name
- NCT07901543
- Testing
- Hereditary cancer preliminary screening chatbot
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Narrow the search
Conditions in oncology
Conditions with their own page on AzTrials, with the number of registered studies.
- Breast Cancer 8,958
- Prostate Cancer 4,507
- Cancer 4,043
- Colorectal Cancer 3,512
- Lung Cancer 3,125
- Non-small Cell Lung Cancer 3,107
- Multiple Myeloma 2,359
- Ovarian Cancer 2,092
- Lymphoma 2,058
- Pancreatic Cancer 1,969
- Gastric Cancer 1,823
- Hepatocellular Carcinoma 1,820
- Leukemia 1,666
- Head and Neck Cancer 1,611
- Acute Myeloid Leukemia 1,483
- Melanoma 1,467
- Cervical Cancer 1,312
- Neoplasms 1,124
- Bladder Cancer 1,120
- Solid Tumor 1,066
- Esophageal Cancer 1,057
- Rectal Cancer 985
- Breast Neoplasms 972
- Metastatic Breast Cancer 912
- Glioblastoma 906
- Endometrial Cancer 867
- Advanced Solid Tumors 842
- Colon Cancer 830
- Solid Tumors 787
- Sarcoma 777
- Advanced Solid Tumor 776
- Unspecified Adult Solid Tumor, Protocol Specific 758
- Chronic Lymphocytic Leukemia 750
- Carcinoma, Non-Small-Cell Lung 677
- Colorectal Neoplasms 666
- Acute Lymphoblastic Leukemia 661
Questions about oncology trials
Which trials are counted as oncology?
Studies whose conditions, or the medical subject headings the registry adds to them, mention any of these terms: cancer, tumor, neoplasm, lymphoma, leukemia, myeloma, melanoma, carcinoma, sarcoma, glioma, glioblastoma. A study can belong to more than one specialty, and the grouping is AzTrials', not the sponsor's.
Are all of these trials recruiting?
No. The lists on this page show studies open to volunteers (recruiting, not yet recruiting or enrolling by invitation), as the sponsor last reported. The full search also includes completed and stopped studies, some with posted results.
How can I refer a patient to one of these trials?
Open the trial and use the contacts and sites it lists; the For doctors view of each trial collects them with the key eligibility criteria. AzTrials does not enrol participants or take referrals.