Cardiovascular DiseasesNCT00005375
Smoking Onset in a Biethnic Population
An observational study of Cardiovascular Diseases and Heart Diseases, run by National Heart, Lung, and Blood Institute (NHLBI).
Trial summary
To conduct a prospective study of the determinants of smoking onset in adolescents attending Memphis City Schools and to determine the unique predictors of smoking onset in Black versus white adolescent females. Read more about this study
- Who is it for?
- Any age, men only
- Conditions the study is for
- Cardiovascular Diseases, Heart Diseases, Lung Diseases
- How many people
- Not given
- Where
- No sites listed yet
- Study dates
- Sep 1993to Jan 2006
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- Men only
- No healthy volunteers
- Child, Adult, Older adult
No eligibility criteria
About this study
To conduct a prospective study of the determinants of smoking onset in adolescents attending Memphis City Schools and to determine the unique predictors of smoking onset in Black versus white adolescent females.
Read the detailed description
BACKGROUND:
Although many smoking prevention programs have been implemented on a large-scale basis, the effectiveness of these programs varies greatly. While these programs have undoubtedly prevented many young adults from starting to smoke, recent smoking initiation rates among females have consistently exceeded the rates of males and smoking initiation rates among Afro-Americans remain at high levels. More information is needed on the reasons for smoking initiation among adolescents, particularly females. Despite considerable interest in this area, virtually nothing is known regarding the reasons for adoption of smoking in Black or white females. Not a single prospective study has evaluated race-and gender-specific models for the prediction of smoking onset. For example, while it is commonly assumed that the weight-reducing qualities of smoking are associated with smoking onset among female adolescents, not a single prospective study has been conducted that documents that weight-related concerns at one age predict smoking onset at a later age.
The study was part of the Collaborative Projects on Women's Health initiative which was proposed by the NHLBI staff, given concept clearance at the February 1992 National Heart, Lung, and Blood Advisory Council, and released as a Request for Applications in April 1992.
DESIGN NARRATIVE:
The study was part of a two grant project on the Collaborative Projects on Women's Health. Dr. Robert Klesges conducted a longitudinal study to assess whether weight concerns of adolescent girls predict smoking onset at a later age. His collaborator, Dr, Linda Eck (R01HL50946), evaluated the role of smoking in dietary intake, physical activity, and metabolic rate and determined the differential effects of smoking and race on the energy balance of African American and white women.
Dr. Klesges' study was renewed in FY 1998 to continue longitudinal observation of factors relating to the onset of smoking in a biracial population of 6,967 boy and girl students first surveyed as seventh graders in 1993-94. The cohort was tracked through the end of high school and two years after high school in order to investigate the determinants of smoking onset both in high school and into the young adult years.
The study was renewed in February 2001 through January 2005 to follow-up participants for four years post-high school to assess the extent of young adult smoking onset and cessation, to determine predictors of smoking onset, and identify predictors of cessation for both early onset and late onset smokers.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases
- Medical subject headings
- Cardiovascular Diseases, Heart Diseases, Lung Diseases
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 May 2000 (estimated)
- Study startSep 1993
- Primary completionJan 2006
- Study completionJan 2006
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (11)Papers the sponsor has linked to this study.
- Other trials for Cardiovascular DiseasesStudies of the same condition, open and under way.
- More trials run by National Heart, Lung, and Blood Institute (NHLBI)The sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
Sponsor and investigators
- Sponsor type
- US National Institutes of Health
- Investigators
- Leslie Robinson, University of Memphis
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00005375
- Sponsor's protocol ID
- 4271
- Status last verified
- Jan 2008
- First submitted
- 25 May 2000
- Last updated
- 29 Jan 2008
- Results posted
- No
Publications
Robinson LA, Klesges RC, Zbikowski SM, Glaser R. Predictors of risk for different stages of adolescent smoking in a biracial sample. J Consult Clin Psychol. 1997 Aug;65(4):653-62. doi: 10.1037//0022-006x.65.4.653.
PubMed 9256567DeBon M, Klesges RC. Adolescents' perceptions about smoking prevention strategies: a comparison of the programmes of the American Lung Association and the Tobacco Institute. Tob Control. 1996 Spring;5(1):19-25. doi: 10.1136/tc.5.1.19.
PubMed 8795854Robinson LA, Klesges RC, Zbikowski SM. Gender and ethnic differences in young adolescents' sources of cigarettes. Tob Control. 1998 Winter;7(4):353-9. doi: 10.1136/tc.7.4.353.
PubMed 10093167Klesges RC, Robinson LA, Zbikowski SM. Is smoking associated with lower body mass in adolescents? A large-scale biracial investigation. Addict Behav. 1998 Jan-Feb;23(1):109-13. doi: 10.1016/s0306-4603(97)00022-1.
PubMed 9468748Robinson LA, Klesges RC. Ethnic and gender differences in risk factors for smoking onset. Health Psychol. 1997 Nov;16(6):499-505. doi: 10.1037//0278-6133.16.6.499.
PubMed 9386994Klesges RC, Elliott VE, Robinson LA. Chronic dieting and the belief that smoking controls body weight in a biracial, population-based adolescent sample. Tob Control. 1997 Summer;6(2):89-94. doi: 10.1136/tc.6.2.89.
PubMed 9291216Proudman JA, Mellen WJ, Hultin HO. Activity of certain liver enzymes in fast- and slow-growing lines of chickens. Poult Sci. 1975 Sep;54(5):1585-96. doi: 10.3382/ps.0541585.
PubMed 1187517Murray DM, Alfano CM, Zbikowski SM, Padgett LS, Robinson LA, Klesges R. Intraclass correlation among measures related to cigarette use by adolescents: estimates from an urban and largely African American cohort. Addict Behav. 2002 Jul-Aug;27(4):509-27. doi: 10.1016/s0306-4603(01)00189-7.
PubMed 12188589Zbikowski SM, Klesges RC, Robinson LA, Alfano CM. Risk factors for smoking among adolescents with asthma. J Adolesc Health. 2002 Apr;30(4):279-87. doi: 10.1016/s1054-139x(01)00394-9.
PubMed 11927240Klesges LM, Johnson KC, Somes G, Zbikowski S, Robinson L. Use of nicotine replacement therapy in adolescent smokers and nonsmokers. Arch Pediatr Adolesc Med. 2003 Jun;157(6):517-22. doi: 10.1001/archpedi.157.6.517.
PubMed 12796230Riedel BW, Blitstein JL, Robinson LA, Murray DM, Klesges RC. The reliability and predictive value of adolescents' reports of initial reactions to smoking. Nicotine Tob Res. 2003 Aug;5(4):553-9. doi: 10.1080/1462220031000118658.
PubMed 12959793
Study at a glance
From the registry record, last updated by the sponsor on 29 Jan 2008. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Smoking Onset in a Biethnic Population
- ClinicalTrials.gov ID
- NCT00005375
- Acronym / sponsor ID
- 4271
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases
- Study type
- Observational
- Recruitment status
- Completed
- Lead sponsor
- National Heart, Lung, and Blood Institute (NHLBI)US National Institutes of Health
- Study start
- Sep 1993
- Primary completion
- Jan 2006 (actual)
- Study completion
- Jan 2006 (actual)
- First posted
- 26 May 2000 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To conduct a prospective study of the determinants of smoking onset in adolescents attending Memphis City Schools and to determine the unique predictors of smoking onset in Black versus white adolescent females.
Detailed description
BACKGROUND:
Although many smoking prevention programs have been implemented on a large-scale basis, the effectiveness of these programs varies greatly. While these programs have undoubtedly prevented many young adults from starting to smoke, recent smoking initiation rates among females have consistently exceeded the rates of males and smoking initiation rates among Afro-Americans remain at high levels. More information is needed on the reasons for smoking initiation among adolescents, particularly females. Despite considerable interest in this area, virtually nothing is known regarding the reasons for adoption of smoking in Black or white females. Not a single prospective study has evaluated race-and gender-specific models for the prediction of smoking onset. For example, while it is commonly assumed that the weight-reducing qualities of smoking are associated with smoking onset among female adolescents, not a single prospective study has been conducted that documents that weight-related concerns at one age predict smoking onset at a later age.
The study was part of the Collaborative Projects on Women's Health initiative which was proposed by the NHLBI staff, given concept clearance at the February 1992 National Heart, Lung, and Blood Advisory Council, and released as a Request for Applications in April 1992.
DESIGN NARRATIVE:
The study was part of a two grant project on the Collaborative Projects on Women's Health. Dr. Robert Klesges conducted a longitudinal study to assess whether weight concerns of adolescent girls predict smoking onset at a later age. His collaborator, Dr, Linda Eck (R01HL50946), evaluated the role of smoking in dietary intake, physical activity, and metabolic rate and determined the differential effects of smoking and race on the energy balance of African American and white women.
Dr. Klesges' study was renewed in FY 1998 to continue longitudinal observation of factors relating to the onset of smoking in a biracial population of 6,967 boy and girl students first surveyed as seventh graders in 1993-94. The cohort was tracked through the end of high school and two years after high school in order to investigate the determinants of smoking onset both in high school and into the young adult years.
The study was renewed in February 2001 through January 2005 to follow-up participants for four years post-high school to assess the extent of young adult smoking onset and cessation, to determine predictors of smoking onset, and identify predictors of cessation for both early onset and late onset smokers.
Study design
Who may qualify
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jan 2008.
- Background: PubMed 9256567Robinson LA, Klesges RC, Zbikowski SM, Glaser R. Predictors of risk for different stages of adolescent smoking in a biracial sample. J Consult Clin Psychol. 1997 Aug;65(4):653-62. doi: 10.1037//0022-006x.65.4.653.
- Background: PubMed 8795854DeBon M, Klesges RC. Adolescents' perceptions about smoking prevention strategies: a comparison of the programmes of the American Lung Association and the Tobacco Institute. Tob Control. 1996 Spring;5(1):19-25. doi: 10.1136/tc.5.1.19.
- Background: PubMed 10093167Robinson LA, Klesges RC, Zbikowski SM. Gender and ethnic differences in young adolescents' sources of cigarettes. Tob Control. 1998 Winter;7(4):353-9. doi: 10.1136/tc.7.4.353.
- Background: PubMed 9468748Klesges RC, Robinson LA, Zbikowski SM. Is smoking associated with lower body mass in adolescents? A large-scale biracial investigation. Addict Behav. 1998 Jan-Feb;23(1):109-13. doi: 10.1016/s0306-4603(97)00022-1.
- Background: PubMed 9386994Robinson LA, Klesges RC. Ethnic and gender differences in risk factors for smoking onset. Health Psychol. 1997 Nov;16(6):499-505. doi: 10.1037//0278-6133.16.6.499.
- Background: PubMed 9291216Klesges RC, Elliott VE, Robinson LA. Chronic dieting and the belief that smoking controls body weight in a biracial, population-based adolescent sample. Tob Control. 1997 Summer;6(2):89-94. doi: 10.1136/tc.6.2.89.
- Background: PubMed 1187517Proudman JA, Mellen WJ, Hultin HO. Activity of certain liver enzymes in fast- and slow-growing lines of chickens. Poult Sci. 1975 Sep;54(5):1585-96. doi: 10.3382/ps.0541585.
- Background: PubMed 12188589Murray DM, Alfano CM, Zbikowski SM, Padgett LS, Robinson LA, Klesges R. Intraclass correlation among measures related to cigarette use by adolescents: estimates from an urban and largely African American cohort. Addict Behav. 2002 Jul-Aug;27(4):509-27. doi: 10.1016/s0306-4603(01)00189-7.
- Background: PubMed 11927240Zbikowski SM, Klesges RC, Robinson LA, Alfano CM. Risk factors for smoking among adolescents with asthma. J Adolesc Health. 2002 Apr;30(4):279-87. doi: 10.1016/s1054-139x(01)00394-9.
- Background: PubMed 12796230Klesges LM, Johnson KC, Somes G, Zbikowski S, Robinson L. Use of nicotine replacement therapy in adolescent smokers and nonsmokers. Arch Pediatr Adolesc Med. 2003 Jun;157(6):517-22. doi: 10.1001/archpedi.157.6.517.
- Background: PubMed 12959793Riedel BW, Blitstein JL, Robinson LA, Murray DM, Klesges RC. The reliability and predictive value of adolescents' reports of initial reactions to smoking. Nicotine Tob Res. 2003 Aug;5(4):553-9. doi: 10.1080/1462220031000118658.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Leslie Robinson
University of Memphis
Questions about this trial
What is this clinical trial studying?
An observational study of Cardiovascular Diseases and Heart Diseases, run by National Heart, Lung, and Blood Institute (NHLBI).
The full registered description is in the About this study section and the official record.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jan 2008. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00005375, which also lists 11 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jan 2008.