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PsoriasisRESPONSENCT00096928

A Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)

An observational study of Psoriasis, run by Genentech, Inc. at 182 sites in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

This was a multicenter, prospective, 5-year surveillance study of approximately 5000 Raptiva-treated patients and approximately 500 non-Raptiva treated patients (formerly 2500 comparison patients who were treated with a biologic therapy other than Raptiva) with chronic moderate to severe plaque psoriasis who were… Read more about this study

Who is it for?
Any age
Conditions the study is for
Psoriasis
How many people
1,846 participants
Where
182 sitesUnited States
Study dates
Mar 2005to Oct 2009
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages Any age
  • All sexes
  • No healthy volunteers
  • Child, Adult, Older adult

Study population: managed care organizations, community or physician practices, and academic centers in the United States

Who may be able to join

  • Have ever had a physician's diagnosis of chronic moderate to severe plaque psoriasis and be a candidate for treatment with Raptiva
  • Are being treated with or initiating Raptiva therapy at the time of enrollment
  • Be able to provide written informed consent
  • Be willing and able to fully to participate for the duration of patient follow-up (5 years)

Who cannot join

  • Have previously received at least one dose of Raptiva and are not currently using or restarting treatment with Raptiva at the time of enrollment

Trial locations and contacts

182 sites in 1 country.

182 sites in 1 country

United States182 sites

  • Curtis W. Hawkins, MD

    Akron, Ohio, 44313

  • Atlanta Dermatology, Vein, and Research Center, LLC

    Alpharetta, Georgia, 30005

  • David Fivenson, MD Dermatology, PLLC

    Ann Arbor, Michigan, 48103

  • Emory University

    Atlanta, Georgia, 30322

  • Fox Valley Dermatology LTD

    Aurora, Illinois, 60502

  • Aventura Medical Research Inc

    Aventura, Florida, 33180

  • Stephen N Horwitz, MD, PA

    Aventura, Florida, 33180

  • Bakersfield Dermatology and Skin Cancer Medical Grp

    Bakersfield, California, 93309

  • James E. Turner, MD, PhD, PC

    Bartlett, Tennessee, 38134

  • Louisiana Dermatology Associates

    Baton Rouge, Louisiana, 70806

  • Great Lakes Research Group, Inc.

    Bay City, Michigan, 48706

  • The Dermatology Center

    Bayside, New York, 11360

  • Dermatology Associates of the Low Country

    Beaufort, South Carolina, 29907

  • Belleville Dermatology Ctr, PA

    Belleville, New Jersey, 07109

  • Dermatology and Laser Center NW

    Bellingham, Washington, 98225

  • Washington Dermatology Center

    Bethesda, Maryland, 20814

  • Total Skin and Beauty Dermatology Center

    Birmingham, Alabama, 35205

  • Brent M Schillinger, MD, PA

    Boca Raton, Florida, 33433

  • The Dermatology and Aesthetic Center

    Boca Raton, Florida, 33486

  • David Hecker, MD

    Boca Raton, Florida, 33496

  • Brigham and Womens' Hospital

    Boston, Massachusetts, 02115

  • Graves Gilbert Clinic

    Bowling Green, Kentucky, 42101

  • Advanced Skin and Laser Center

    Brentwood, Tennessee, 37027

  • Fletcher Allen Health Care

    Burlington, Vermont, 05401

  • DataPharm, Inc.

    Canfield, Ohio, 44406

  • Dermatology Specialists of West Georgia

    Carrollton, Georgia, 30117

  • Centennial Cosmetic Surgery and Dermatology

    Centennial, Colorado, 80112

  • Christie Clinic

    Champaign, Illinois, 61820

  • Dr. Marta Hampton

    Charleston, South Carolina, 29407

  • Dermatology and Laser Center of Charleston, PA

    Charleston, South Carolina, 29414

  • Mid-Charlotte Dermatology and Research PLLC

    Charlotte, North Carolina, 28211

  • Skin Care Physicians of Chestnut Hill

    Chestnut Hill, Massachusetts, 02467

  • Northwestern University

    Chicago, Illinois, 60611

  • Danilo V. Del Campo

    Chicago, Illinois, 60641

  • University Dermatology Consultants, Inc.

    Cincinnati, Ohio, 45242

  • University Hospitals Cleveland

    Cleveland, Ohio, 44106

  • The Cleveland Clinical Foundation

    Cleveland, Ohio, 44195

  • Texas Familicare Clinical Research

    Colleyville, Texas, 76034

  • East Metro Dermatology

    Conyers, Georgia, 30012

  • Dermatology Associates and Research

    Coral Gables, Florida, 33134

  • Dermatology Center of Northwest Indiana

    Crown Point, Indiana, 46307

  • Baylor Research Institute

    Dallas, Texas, 75246-1613

  • Dermatology Associates Of Western Connecticut

    Danbury, Connecticut, 06810

  • Deep South Dermatology

    Daphne, Alabama, 36526

  • Wright State University

    Dayton, Ohio, 45408

  • Eastern Washington Dermatology

    Dayton, Washington, 99328

  • Colorado Medical Research Center, Inc.

    Denver, Colorado, 80210

  • Altoona Center For Clinical Research

    Duncansville, Pennsylvania, 16635

  • Duke University Medical Center

    Durham, North Carolina, 27710

  • Windsor Dermatology

    East Windsor, New Jersey, 08520

  • T. Joseph Raoof, MD, Inc.

    Encino, California, 91436

  • Meridian Skin Cancer Center

    Englewood, Colorado, 80112

  • Jan K. Brydon, MD

    Erie, Pennsylvania, 16507

  • Three Rivers Dermatology

    Fort Wayne, Indiana, 46804

  • Minarets Medical Group

    Fresno, California, 93711

  • Associates In Research, Inc.

    Fresno, California, 93720

  • The Dermatology Center

    Gadsden, Alabama, 35901

  • SunValley Arthritis Center Ltd

    Glendale, Arizona, 85308-7100

  • Rivergate Dermatology

    Goodlettsville, Tennessee, 37072

  • Psoriasis and Eczema Treatment Center of Western Michigan PLLC

    Grand Rapids, Michigan, 49503

  • Northern Colorado Allergy and Asthma Clinic

    Greeley, Colorado, 80634

  • Advanced Dermatology and Laser Center

    Greenville, South Carolina, 29615

  • Hudson Dermatology and Skin Cancer Center

    Hoboken, New Jersey, 07030

  • Queens Medical Center

    Honolulu, Hawaii, 96813

  • West Houston Dermatology, PA

    Houston, Texas, 77082

  • Hudson Dermatology

    Hudson, Ohio, 44236

  • Medical Affiliated Research Center, Inc.

    Huntsville, Alabama, 35801

  • Ruth A. Yates, MD

    Huntsville, Alabama, 35801

  • Dermatology Associates, PC

    Indianapolis, Indiana, 46240

  • Investigators Research Group

    Indianapolis, Indiana, 46254

  • Dawes Fretzin Clinical Research Group, LLC

    Indianapolis, Indiana, 46256

  • Delta Dermatology Medical Group

    Inglewood, California, 90301

  • University of Iowa Health Care

    Iowa City, Iowa, 52242

  • North Florida Dermatology Associates, PA

    Jacksonville, Florida, 32204

  • Coastal Dermatology

    Jacksonville, Florida, 32246

  • Jeffrey Schachne, MD

    Jefferson Valley, New York, 10535

  • Clinical Partners, LLC

    Johnston, Rhode Island, 02919

  • Genesis Dermatology

    Jupiter, Florida, 33458

  • Wells Institute for Health Awareness

    Kettering, Ohio, 45429

  • Dermatology Associates of Kingsport, PC

    Kingsport, Tennessee, 37660

  • Lloyd J. Cleaver, DO, LLC

    Kirksville, Missouri, 63501

  • Dermatology Associates Of Knoxville

    Knoxville, Tennessee, 37917

  • The Skin Wellness Center, P.C.

    Knoxville, Tennessee, 37922

  • Dermatology and Advanced Aesthetics

    Lake Charles, Louisiana, 70601

  • Woodson Dermatology

    Las Vegas, Nevada, 89128

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756

  • South Lincoln Dermatology

    Lincoln, Nebraska, 68502

  • Advanced Dermatology

    Lincolnshire, Illinois, 60069

  • BGPDS Dermatology

    Little Rock, Arkansas, 72205

  • Fairmont Dermatology Medical Associates, Inc

    Lodi, California, 95242

  • Rocky Mountain Dermatology

    Logan, Utah, 84341

  • Dermatology Associates

    Los Angeles, California, 90045

  • Derm Research, PLLC

    Louisville, Kentucky, 40217

  • Atlantic Dermatologic Associates, LLP

    Lynbrook, New York, 11563

  • Education and Research Foundation

    Lynchburg, Virginia, 24501

  • Dermatologic Surgery Specialists, Inc.

    Macon, Georgia, 31217

  • Atlantic Skin and Cosmetic Surgery Group, PC

    Malvern, Pennsylvania, 19355

  • Smith Clinic

    Marion, Ohio, 43302

  • Jan Fu, MD and PhD

    Mason, Ohio, 45040

  • University of Miami Dept. of Dermatology and Cutaneous Surgery

    Miami, Florida, 33136

  • Callender Skin and Laser Center

    Mitchellville, Maryland, 20721

  • Skin Care Center Of Southern Illinois

    Mount Vernon, Illinois, 62864

  • Elizabeth A. Abel, MD

    Mountain View, California, 94040

  • Germain Dermatology Associates

    Mt. Pleasant, South Carolina, 29464

  • Murfreesboro Dermatology Clinic

    Murfreesboro, Tennessee, 37129

  • Nashua Dermatology Associates

    Nashua, New Hampshire, 03062

  • Nashua Dermatology

    Nashua, New Hampshire, 03062

  • Dermatology Research Associates Inc.

    Nashville, Tennessee, 37203

  • Tennessee Clinical Research Center

    Nashville, Tennessee, 37215

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232-2600

  • The Dermatology Center PSC

    New Albany, Indiana, 47150

  • Virginia Clinical Research

    Norfolk, Virginia, 23507

  • Sooner Palmer Circle

    Norman, Oklahoma, 73069

  • DiGiovanna Family Care Center

    North Massapequa, New York, 11758

  • East Penn. Dermatology

    North Wales, Pennsylvania, 19454

  • Dermatology Associates

    Norwood, Massachusetts, 02062

  • South Nassau Dermatology, P.C.

    Oceanside, New York, 11572

  • Park Avenue Dermatology

    Orange Park, Florida, 32073

  • The Hillcrest Dermatology Center

    Orangeburg, South Carolina, 29118

  • Central Florida Dermatology Associates, Inc.

    Orlando, Florida, 32806

  • Kansas City Dermatology, PA

    Overland Park, Kansas, 66215

  • Dermatology Medical Group of Oxnard

    Oxnard, California, 93030

  • Dermatology Consultants of Broward

    Pembroke Pines, Florida, 33028

  • Alliance Dermatology and MOHS

    Phoenix, Arizona, 85032

  • Dermatology Research by Dr. Gary L. Heller

    Pinellas Park, Florida, 33781

  • The Dermatology Center of Indiana

    Plainfield, Indiana, 46168

  • Dermatology Associates Of Plymouth Meeting

    Plymouth Meeting, Pennsylvania, 19462

  • Northwest Cutaneous Research Specialists

    Portland, Oregon, 97210

  • Great Lakes Dermatology- Racine

    Racine, Wisconsin, 53406

  • Dermatology and Skin Cancer Center

    Raleigh, North Carolina, 27607

  • Andrus and Associates Dermatology, P.A.

    Raleigh, North Carolina, 27609

  • Nevada Center For Dermatology, Ltd

    Reno, Nevada, 89511

  • Skin Cancer and Dermatology Institute

    Reno, Nevada, 89511

  • Aylesworth Dermatology, SC

    Rhinelander, Wisconsin, 54501

  • Karen S. Harkaway, MD, LLC

    Riverside Park, New Jersey, 08075

  • Helendale Dermatology and Medical Spa

    Rochester, New York, 14609

  • Skin Search and Dermatology Associates of Rochester

    Rochester, New York, 14623

  • The Center for Dermatology at Lifetime Health

    Rochester, New York, 14623

  • Thomas O. McMeekin MD, PC

    Rochester, New York, 14623

  • Hull Dermatology, PA

    Rogers, Arkansas, 72758

  • Northwest Georgia Dermatology

    Rome, Georgia, 30165

  • Associates In Dermatology Research

    Rutherford, New Jersey, 07070

  • Dermatology Clinical Research Center of San Antonio

    San Antonio, Texas, 78229

  • Dermatology Associates of San Antonio

    San Antonio, Texas, 78258

  • Kent Carson, MD

    San Jose, California, 95123

  • East Bay Psoriasis Treatment Center

    San Ramon, California, 94583

  • Clinical Research Specialists, Inc.

    Santa Monica, California, 90404

  • Schaumburg Dermatology

    Schaumburg, Illinois, 60194

  • Dermatology Associates, PLLC

    Seattle, Washington, 98101

  • Highland Clinic, APMC

    Shreveport, Louisiana, 71105

  • Dakota Dermatology, LTD

    Sioux Falls, South Dakota, 57108

  • Gwinnett Clinical Research Center Inc.

    Snellville, Georgia, 30078

  • Spokane Dermatology Clinic

    Spokane, Washington, 99204

  • Northwest Dermatology

    Spokane, Washington, 99218

  • Clinical Research of Tampa Bay, Inc.

    Spring Hill, Florida, 34609

  • Saint Louis University

    St Louis, Missouri, 63104

  • Central Dermatology, PC

    St Louis, Missouri, 63117

  • Jacquelyn B. Garrett

    St Louis, Missouri, 63136

  • Karen E Forsman, MD Dermatology LLC

    St Louis, Missouri, 63141

  • Dermatology Associates

    Staten Island, New York, 10314

  • DermResearchCenter of New York, Inc

    Stony Brook, New York, 11790

  • Judith Andreano MD, Inc.

    Strongsville, Ohio, 44136

  • Arthritis Health Associates

    Syracuse, New York, 13210

  • Southeastern Research Associates, Inc.

    Taylors, South Carolina, 29687

  • Toccoa Clinic Medical Associates

    Toccoa, Georgia, 30577

  • Kansas Medical Clinic

    Topeka, Kansas, 66614

  • Healthcare Partners Medical Group

    Torrance, California, 90503

  • Somerset Skin Centre

    Troy, Michigan, 48084

  • Alan Olmstead, MD

    Twin Falls, Idaho, 83301

  • Skin and Laser Surgery Center PC

    Tysons Corner, Virginia, 22182

  • Skin Physicians and Surgeons Medical Group, Inc.

    Upland, California, 91786

  • Virginia Beach Dermatology Associates

    Virginia Beach, Virginia, 23464

  • DataPharm, Inc

    Warren, Ohio, 44483

  • George Washington University Medical Center

    Washington D.C., District of Columbia, 20037

  • M. Siegel, MD PC

    Waterford, Michigan, 48328-3735

  • Randall Dermatology, PC

    West Lafayette, Indiana, 47906

  • Buffalo Medical Group, PC

    Williamsville, New York, 14221

  • Atlantic Dermatology Associates PA

    Wilmington, North Carolina, 28401

  • Wilmington Health Associates

    Wilmington, North Carolina, 28401

  • Dermatology Associates, Inc.

    Winchester, Virginia, 22601

  • Worcester Dermatology

    Worcester, Massachusetts, 01608

  • Linda Susan Marcus, MD, FAAD

    Wyckoff, New Jersey, 07481

Other trials in United States

About this study

Official title: Raptiva Epidemiologic Study of Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Psoriasis (RESPONSE)

This was a multicenter, prospective, 5-year surveillance study of approximately 5000 Raptiva-treated patients and approximately 500 non-Raptiva treated patients (formerly 2500 comparison patients who were treated with a biologic therapy other than Raptiva) with chronic moderate to severe plaque psoriasis who were candidates for treatment with Raptiva.

Conditions
Psoriasis
Keywords
Plaque Psoriasis, RESPONSE, Raptiva, efalizumab
Medical subject headings
Psoriasis

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Nov 2004 (estimated)
  2. Study startMar 2005
  3. Study completionOct 2009

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
1,846 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT00096928
Sponsor's protocol ID
ACD3101g
Acronym
RESPONSE
Status last verified
Mar 2011
First submitted
17 Nov 2004
Last updated
2 Jul 2015
Results posted
No

Questions about this trial

What is this clinical trial studying?

An observational study of Psoriasis, run by Genentech, Inc. at 182 sites in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 2 Jul 2015. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 182 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT00096928.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jul 2015.

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