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DepressionNCT00279526

Depression and Increased Health Services Utilization Among Elderly Primary Care Patients

An observational study of Depression, run by Soroka University Medical Center at 1 site in Israel.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The increase in life expectancy in the 21st century has resulted in a major growth in the prevalence of age-related diseases and conditions. Depression has been found to be the most prevalent among the various mental disorders in later life. Read more about this study

Who is it for?
Ages 65 years and older
Conditions the study is for
Depression
How many people
450 participants
Where
1 siteIsrael
Study dates
Apr 2006to Dec 2006
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 65 years and older
  • All sexes
  • No healthy volunteers
  • Older adult

Who may be able to join

  • Age 65 or older,
  • Clalit health organization client
  • Outpatient
  • Hebrew or English or Russian speaker
  • Living in Beer Sheva

Who cannot join

  • Known diagnosis of depression, major depression, bipolar disorder, psychosis, dementia or substance abuse
  • Current acute illness

Trial locations and contacts

1 site in 1 country.

Israel1 site
  • Department of Family Medicine, Faculty of Health Sciences, Ben Gurion University of the Negev

    Beersheba

Other trials in Israel

About this study

The increase in life expectancy in the 21st century has resulted in a major growth in the prevalence of age-related diseases and conditions. Depression has been found to be the most prevalent among the various mental disorders in later life. It was emphasized that depression in the elderly is a persistent or recurrent disorder resulting from psychosocial stress or physiologic effects of disease and can lead to disability, cognitive impairments, intensified symptoms of other medical conditions and increased utilization of health care services. Due to the rapidly aging population, depression is a serious public health concern that has a great impact on quality of life and may lay a considerable burden on the health care systems. However depression among the elderly may prove to be hard to diagnose since in aged persons depressive symptoms are often masked by somatic complaints or by cognitive impairments. Consequently depression is often under diagnosed and the patients continue to visit constantly the nurse or the physician without getting an adequate answer to their problem. For that reason over utilization of health care services may be an indicator to the presence of undiagnosed depression. The purpose of this study is to examine the relationships between socio-demographic variables, high primary care utilization and depressive symptomatology among aged patients.

Read the detailed description

Introduction The number of Israel's elderly (65 plus) has increased from just 85,200 (4.8% of the population) in 1955 to approximately 670,000 people (about 10%) in 2003 (Brodsky et al., 2005). According to the most conservative of three projections offered by the Israeli Central Bureau of Statistics (CBS), the number of seniors is expected to be approximately 676,500 (9.8% of the population) in 2005, to rise to 722,500 people (10.7% of the population) by 2010 and increase to 1,025,800 (almost 12% of the population) by the year 2020.

The increase in life expectancy in the 20th century has resulted in a major growth in the prevalence of age-related diseases and conditions. Depression has been found to be the most prevalent among various mental disorders in later life and is the third most common reason for consultation in primary care (Shah, 1992). Research shows that 10-15% of the persons over 65 years of age suffer from various levels of depressive symptoms (Jacob\& Palmer, 1998).

Sadock \& Sadock (2003) state that depression among elderly may reach up to 15 percent and among these suffering from dementia from 25- 50 percent. Israeli studies show similar rates of depressive symptomatology as performed in other Western countries. A prevalence of 21.5 percent of depressive symptomatology was found among a random sample of 937 Israeli adults. (Iancu et al., 2003).

Depression represents a heterogeneous set of disorders, usually characterized by sad mood and inability to experience pleasure. Among the elderly it often may present itself atypically, with somatic symptoms dominating the clinical picture (Jacob \& Palmer, 1998). Common physical complaints, start with the most common features as loss of energy or fatigue, unexplained pain, gastrointestinal symptoms, headache, dizziness, palpitations, heartburn, numbness, loss of appetite, insomnia specifically early morning awakening. In general, the more unexplained somatic complaints and physical symptoms a patient have, the higher the likelihood of depression (Glass 2003). Elderly depression impairs significantly the quality of life by leading to disability, cognitive impairments, intensified symptoms from medical conditions and increases utilization of health care services and the direct and indirect medical costs (Luber et al., 2001).

Herrman et al.,( 2002) argue that health care utilization among depressed patients is higher then among those without depression. Elderly with depressive symptoms found to be at least as twice as likely to use emergency department and medical inpatient hospital services compared to patients without depressive symptomatology ( Himelhoch et al., 2002). Simon \& Ormel(1995) as well as Katon et al. (2003) stated that patients with depressive symptoms account for 43-52% higher health care costs than patients without depressive symptoms.

The increase in costs associated with depressive symptoms was noted even after adjusting for the severity of chronic medical illness (Glass, 2003). According to the WHO the significance of illness burden attributable to depression increases with age and thus will grow further by the year 2020 based upon projected demographic shifts towards an older population (Peveler et al., 2002).

This trend was showed in Israel by Brodsky et al.( 2005). They reported an elderly average of 11.5 visits at the FP per year while, in the USA, only 25% of the elderly population visited any physician 10 or more times annually - including visits to the ER and home visits (Health, United States,2003).

Consequently detecting and treating elderly patients with depressive symptoms in Israel, may be cost-effective and produce improvement in health and well-being for the money spent in the care of these older adults.

However depression in the aged patient may be atypical in nature and more difficult to diagnose from that in the general population. Therefore it is often under-diagnosed and under-treated (Jacob \& Palmer, 1998). In contrast to younger depressed patients, elderly patients often avoid reporting or showing that their mood level and tend to hide their state of disease or, worse, they lack the consciousness of the disease and think that enjoying life less than before is an inevitable consequence of aging. Moreover, elderly sometimes attribute their depressive symptoms to general medical conditions. Other factors that may hinder distinguishing depression from other conditions are also concomitant diseases, especially dementia, polypharmacy and drug reactions (Glass, 2003). Furthermore Hybels et al. (2001) compared in their study the demographic and risk factor profiles of elderly individuals with less and more severe depression. The obtained results indicated the need to recognize that elderly adults who do not meet the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for depression, and those who fall below the threshold on instruments such as the Center for Epidemiologic Studies-Depression scale (CES-D), may still experience depressive symptomatology that warrant attention.

The current scales used today measure physical deterioration as part of the depressive state, while among the older people these are part of the aging process and may confuse the therapist. The Geriatric Depression Scale (GDS) is a more specific tool for the measurement in this age group. It was developed during the 80's (Brink et al., 1982) proven valid and reliable at 1986 and was translated to many languages including Hebrew. (Zalsman et al., 1998). Today it is one of the most widely used instruments for the screening of depression among the elderly population.

To simplify the screening process a Yale Task Force on Geriatric Assessment has recommended the use of a single question, "Do you often feel sad or depressed?" (Lachs et al., 1990). Mahoney et al.( 1994 ) found this question as a valid and reliable short-form alternative.

In conclusion depression is a prevalent mental disorder in later life and a considerable impending public health problem since it may lay unnecessary cost burden on one hand and is difficult to diagnose on the other. Consequently, there is a need to find the most effective ways for early detection of this condition. This study will examine the question whether high health care services utilization and/ or sociodemographic background may predict the presence of depression among aged patients.

Objectives:

The purposes of this study is to examine the relationships between socio-demographic variables, comorbidity, depressive symptomatology and high primary care utilization.

METHOD:

Participants:

The study will be conducted in 10 primary health care clinics in urban communities of Beersheva, Israel. According to the average health care utilization, 11.5 visits to the FP per year (Brodsky et al., 2005)) among elderly in Israel, we classify two groups: "low care utilizers" with ≤ 6 visits per year and "high care utilizers" with ≥ 16 visits. Primary lists of "high and low care utilizer" will be obtained by query to "Clicks" electronic medical chart system ( Roshtov Soft wear industry ltd.) .

Conditions
Depression
Keywords
Depression, Health services utilization, Elderly, Primary Care
Medical subject headings
Depression, Patient Acceptance of Health Care

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted19 Jan 2006 (estimated)
  2. Study startApr 2006
  3. Study completionDec 2006

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Natural history
Time perspective
Other
Enrolment
450 participants
IDs, dates and publications
ClinicalTrials.gov ID
NCT00279526
Sponsor's protocol ID
sor417105ctil
Status last verified
May 2007
First submitted
18 Jan 2006
Last updated
25 May 2007
Results posted
No

Questions about this trial

What is this clinical trial studying?

An observational study of Depression, run by Soroka University Medical Center at 1 site in Israel.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 25 May 2007. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Israel. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 May 2007.

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