HealthyNCT00357838
Pulse Waves and Tongue Diagnosis Differences Between Follicular and Luteal Phase in Normal Healthy Women
An observational study of Healthy, run by China Medical University Hospital at 1 site in Taiwan.
Trial summary
We hypothesized that there's difference between follicular phase and luteal phase of normal women in radial pulse waves and tongue figures. Read more about this study
- Who is it for?
- Ages 21 to 40 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy
- How many people
- Not given
- Where
- 1 siteTaiwan
- Study dates
- Jul 2006to not given
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 40 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Nornal period I/D=28-35/3-5 (eumenorrheic)
- age:21-40
- No use of oral pills in past 6 months
- BMI1: 8.5-24.9
- No history of smoke, alcohol or drug abuse
- No regular exercise in past 3 month
Who cannot join
- CVD, hepatic, renal disease
- psychological disease
- Thyroid disease
Trial locations and contacts
1 site in 1 country.
Taiwan1 site, 1 recruiting
- Recruiting
China Medical Univerity Hospital
Dawan
Shan Yu, MD, 886-4-22052121
About this study
We hypothesized that there's difference between follicular phase and luteal phase of normal women in radial pulse waves and tongue figures.
Read the detailed description
As comparing with follicular and menstrual phases of the cycle, in women during the luteal phase, the heart rate, body temperature, foot skin temperature and body weight were significantly increased. Tongue inspection and pulse examination are two methods that Chinese medical doctors are used in the diagnosis of patterns. Pulse wave analysis of the radial artery is a non-invasive, widely applicable technique for assessing cardiovascular function. Radial artery waveforms have been demonstrated being associated with the blood pressure wave of ascending and central aorta, the function of left ventricle , the arterial wall properties and the endothelial function. Even when measure locally, carries characteristic information from the whole arterial system because of reflection of waves at distinct sites of the arterial system. Examination of the changes of the arterial pulse wave between follicular phase may offer valuable insights into cardiovascular physiologic feature in menstrual cycle. The objective of this study was to test the hypothesis that the cyclic variations in hemodynamic and volume parameters during the menstrual cycle among normal healthy women. To that end we compared the following parameter of radial pulse contour between late follicular and late luteal time point: percussion wave, the difference between dicrotic wave and dicrotic notch, and the area of the wave.
- Conditions
- Healthy
- Keywords
- normal healthy women
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jul 2006 (estimated)
- Study startJul 2006
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HealthyStudies of the same condition, open and under way.
- More trials run by China Medical University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Time perspective
- Other
Sponsor and investigators
- Lead sponsor
- China Medical University Hospital
- Sponsor type
- University, hospital or other
- Investigators
- Shan-Yu Su, MD, Study chair, China Medical University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00357838
- Sponsor's protocol ID
- DMR95-IRB-64
- Status last verified
- Jul 2006
- First submitted
- 27 Jul 2006
- Last updated
- 18 Oct 2006
- Results posted
- No
Publications
Spaanderman ME, Van Beek E, Ekhart TH, Van Eyck J, Cheriex EC, De Leeuw PW, Peeters LL. Changes in hemodynamic parameters and volume homeostasis with the menstrual cycle among women with a history of preeclampsia. Am J Obstet Gynecol. 2000 May;182(5):1127-34. doi: 10.1067/mob.2000.105342.
PubMed 10819846
Study at a glance
From the registry record, last updated by the sponsor on 18 Oct 2006. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pulse Waves and Tongue Diagnosis Differences Between Follicular and Luteal Phase in Normal Healthy Women
- ClinicalTrials.gov ID
- NCT00357838
- Acronym / sponsor ID
- DMR95-IRB-64
- Conditions
- Healthy
- Keywords
- normal healthy women
- Study type
- Observational
- Recruitment status
- Unknown status
- Lead sponsor
- China Medical University HospitalUniversity, hospital or other
- Study start
- Jul 2006
- First posted
- 28 Jul 2006 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
We hypothesized that there's difference between follicular phase and luteal phase of normal women in radial pulse waves and tongue figures.
Detailed description
As comparing with follicular and menstrual phases of the cycle, in women during the luteal phase, the heart rate, body temperature, foot skin temperature and body weight were significantly increased. Tongue inspection and pulse examination are two methods that Chinese medical doctors are used in the diagnosis of patterns. Pulse wave analysis of the radial artery is a non-invasive, widely applicable technique for assessing cardiovascular function. Radial artery waveforms have been demonstrated being associated with the blood pressure wave of ascending and central aorta, the function of left ventricle , the arterial wall properties and the endothelial function. Even when measure locally, carries characteristic information from the whole arterial system because of reflection of waves at distinct sites of the arterial system. Examination of the changes of the arterial pulse wave between follicular phase may offer valuable insights into cardiovascular physiologic feature in menstrual cycle. The objective of this study was to test the hypothesis that the cyclic variations in hemodynamic and volume parameters during the menstrual cycle among normal healthy women. To that end we compared the following parameter of radial pulse contour between late follicular and late luteal time point: percussion wave, the difference between dicrotic wave and dicrotic notch, and the area of the wave.
Study design
- Time perspective
- Other
Who may qualify
- Ages
- 21 to 40 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Nornal period I/D=28-35/3-5 (eumenorrheic)
- age:21-40
- No use of oral pills in past 6 months
- BMI1: 8.5-24.9
- No history of smoke, alcohol or drug abuse
Key exclusion criteria (3 listed)
- CVD, hepatic, renal disease
- psychological disease
- Thyroid disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Oct 2006.
- Background: PubMed 10819846Spaanderman ME, Van Beek E, Ekhart TH, Van Eyck J, Cheriex EC, De Leeuw PW, Peeters LL. Changes in hemodynamic parameters and volume homeostasis with the menstrual cycle among women with a history of preeclampsia. Am J Obstet Gynecol. 2000 May;182(5):1127-34. doi: 10.1067/mob.2000.105342.
Related trials for Healthy
Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Physical Activity, Body Image
Not yet recruitingPhase 1
A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
Atopic Dermatitis
Recruiting
Colon-delivered Riboflavin and Gut Microbiota Composition
Microbiome Dysbiosis, Gut Health
Not yet recruiting
Neuroergonomic Analysis of a Brain-Computer Interface Device (BCI)
Healthy Volunteers - Male and Female
RecruitingPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy Volunteer, Atopic Dermatitis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Shan-Yu Su, MD study chair
China Medical University Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Healthy, run by China Medical University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 18 Oct 2006. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Shan-Yu Su, MD (886-4-22052121 ext. 5065, shanyusu@yahoo.com.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00357838, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Oct 2006.