AzTrials
AzTrials

PsoriasisATLASNCT00454701

Assessment and Tracking of Long-term Alefacept Safety

An observational study of Psoriasis, run by Astellas Pharma Inc at 268 sites in 2 countries.

Terminated

Stopped early. The study ended before it was planned to and will not resume.

Official record
Search all trials

Trial summary

Subjects exposed to alefacept are to be enrolled. Subjects will be contacted every 6 months to gather general health information. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Psoriasis
What is being tested?
Alefacept exposure
How many people
1,897 participants
Where
268 sitesin 2 countries
Study dates
Jun 2003to Feb 2012
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: Patients treated with alefacept for chronic plaque psoriasis

Who may be able to join

  • Psoriasis patients who are prescribed alefacept consistent with product labeling are eligible for enrollment.

Who cannot join

None listed.

Trial locations and contacts

268 sites in 2 countries.

268 sites in 2 countries

United States241 sites
  • Paul S. Takiguchi- MD- Inc.

    ‘Aiea, Hawaii, 96701

  • Davie Dermatology

    Advance, North Carolina, 27006

  • Derm & Skin Cancer Surgery Center

    Allen, Texas, 75013

  • Jerri L. Johnson MD, PA

    Altamonte Springs, Florida, 32701

  • Arlington Center for Dermatology

    Arlington, Texas, 76011

  • Altman Dermatology Associates

    Arlington Heights, Illinois, 60005

  • Skyland Dermatology and Psychiatry

    Asheville, North Carolina, 28803

  • William S. Mirando, MD, LLC

    Ashtabula, Ohio, 44004-4985

  • Emory University School of Medicine

    Atlanta, Georgia, 30322

  • Darren Casey

    Atlanta, Georgia, 30327

  • Georgia Skin Specialists

    Atlanta, Georgia, 30327

  • Peachtree Dermatology Associates

    Atlanta, Georgia, 30327

  • Family Dermatology-Cynthia A. Abbott, MD

    Atlanta, Georgia, 30328

  • Midsouth Dermatology and Skin Cancer Center

    Bartlett, Tennessee, 38134

  • LA Dermatology Assoc LLC

    Baton Rouge, Louisiana, 70809

  • Dermatology Associates of the Low Counties

    Beaufort, South Carolina, 29907

  • Robert M. Stiegel- M.D. LTD

    Beaver, Pennsylvania, 15009

  • Benjamin Bernstein

    Bel Air, Maryland, 21014

  • Bellaire Dermatology Associates

    Bellaire, Texas, 77401

  • Dermatology & Laser Center Northwest

    Bellingham, Washington, 98225

  • Lehigh Valley Dermatology

    Bethlehem, Pennsylvania, 18018

  • Northeast Dermatology

    Beverly, Massachusetts, 01915

  • Total Skin and Beauty Dermatology Center

    Birmingham, Alabama, 35205

  • Janet Cash

    Birmingham, Alabama, 35213

  • Thomas Brander

    Bloomington, Illinois, 61701

  • Advanced Dermatology Associates, PC

    Bloomington, Indiana, 47403

  • Center for Dermatology

    Boca Raton, Florida, 33428

  • Jodi Fiedler

    Boca Raton, Florida, 33428

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115

  • Advanced Skin & Laser Center

    Brentwood, Tennessee, 37027

  • Jeremy Moss, MD

    Bridgeport, Connecticut, 06606

  • Buffalo Medical Group

    Buffalo, New York, 14221

  • Jeffrey N Samuelson

    Burnsville, Minnesota, 55337

  • Calumet Dermatology Associates S.C.

    Calumet City, Illinois, 60409

  • Dermatology and Skin Surgery Center, PA

    Celebration, Florida, 34747

  • Advanced Dermatology

    Centennial, Colorado, 80111

  • Eugene Conte

    Centerville, Ohio, 45459

  • Christie Clinic

    Champaign, Illinois, 61820

  • Marta Hampton

    Charleston, South Carolina, 29407

  • Rheumatology Associates

    Charleston, South Carolina, 29407

  • Curtis W. Schupbach- MD

    Charlotte, North Carolina, 28204

  • The Dermatology Group LLC

    Chevy Chase, Maryland, 20815

  • Cheyenne Dermatology- P.C.

    Cheyenne, Wyoming, 82001

  • Danilo Del Campo

    Chicago, Illinois, 60641

  • University Dermatology Consultants, Inc.

    Cincinnati, Ohio, 45242

  • Wendy McFalda, DO

    Clarkston, Michigan, 48346

  • Drs. Iacobelli & DiGregorio, PC

    Clinton Township, Michigan, 48038

  • The Dermatology Group, LLC

    Columbia, South Carolina, 29201

  • McClerklin Skin and Laser Center

    Columbia, South Carolina, 29203

  • Allen B. Filstein, MD

    Conyers, Georgia, 30012

  • East Metro Dermatology, PC

    Conyers, Georgia, 30012

  • Melissa Knuckles

    Corbin, Kentucky, 40701

  • Alpha Therapy Center

    Corpus Christi, Texas, 78404

  • Spencer Dermatology Associates LLC

    Crawfordsville, Indiana, 47933

  • Mitchell Bressack

    Crown Point, Indiana, 46307

  • Raymond Blackburn

    Dallas, Texas, 75235

  • Martha Hickmann, MD

    Dayton, Ohio, 45459

  • Brent M Schillinger

    Delray Beach, Florida, 33483

  • Dermatology & Laser Center at Harvard Park, PLLC

    Denver, Colorado, 80210

  • North Atlanta Dermatology

    Duluth, Georgia, 30096

  • Psoriasis Treatment Center of Central NJ

    East Windsor, New Jersey, 08520

  • Advancements In Derm

    Edina, Minnesota, 55435

  • Michael A. Greenberg, MD, Ltd.

    Elk Grove Village, Illinois, 60007

  • Dermatology & Advanced Skin Care

    Ellicott City, Maryland, 21043

  • Joyce Lender

    Elyria, Ohio, 44035

  • Jan Brydon

    Erie, Pennsylvania, 16507

  • Bay Shore Dermatology & Laser Surgery Center

    Fairhope, Alabama, 36532

  • Ozark Dermatology Clinic

    Fayetteville, Arkansas, 72703

  • Bruce Goldstein

    Florence, Massachusetts, 01062

  • Bruce S. Stein

    Flushing, New York, 11355

  • Cyril E Severns

    Fort Smith, Arkansas, 72902

  • Fort Wayne Dermatology

    Fort Wayne, Indiana, 46804

  • Betty J. Rajan

    Fort Worth, Texas, 76107

  • East Bay Dermatology Medical Group Inc. DBA Center for Dermatology, Cosmetic & Laser Surgery, Inc

    Fremont, California, 94538

  • East Bay Dermatology Medical Group Inc., DBA Center for Dermatology, Cosmetic and Laser Surgery

    Fremont, California, 94538

  • Advanced Dermatology

    Fresh Meadows, New York, 11365

  • Minarets Medical Group, Inc.

    Fresno, California, 93711

  • Jack C. Scott

    Fridley, Minnesota, 55432

  • Steven E. Prawer

    Fridley, Minnesota, 55432

  • Eric Baum

    Gadsden, Alabama, 35901

  • Northeast Dermatology & Cosmetic Surgery

    Gahanna, Ohio, 43230

  • Frank De Mento

    Garden City, New York, 11530

  • Garden City Dermatology, P.C.

    Garden City, New York, 11530

  • Lisa Garner

    Garland, Texas, 75043

  • John J. Guagenti, MD

    Glendale, California, 91204

  • Rivergate Dermatology Research Center

    Goodlettsville, Tennessee, 37072

  • D.B.A. Colorado West Dermatology

    Grand Junction, Colorado, 81501

  • Psoriasis and Eczema Treatment Center of Western Michigan

    Grand Rapids, Michigan, 49503

  • Layton Avenue Dermatology

    Greenfield, Wisconsin, 53221

  • John Humeniuk

    Greenville, South Carolina, 29605

  • Dimitri Dermatology

    Gretna, Louisiana, 70056

  • Eric R. Wolf, MD

    Groton, Connecticut, 06340

  • The Dermatology Clinic- PLLC

    Gulfport, Mississippi, 39503

  • North Suburban Dermatology Associates

    Gurnee, Illinois, 60031

  • David Amato

    Harrisburg, Pennsylvania, 17109

  • Saye & Gette Dermatology Associates, PC

    Harrisburg, Pennsylvania, 17112

  • Mark Gallardo

    Hattiesburg, Mississippi, 39402

  • Great Plains Dermatology- P.A.

    Hays, Kansas, 67601

  • Associated Dermatology

    Helena, Montana, 59601

  • Chad Mathews

    Hermitage, Pennsylvania, 16148

  • A.G.A. Clinical Trials

    Hialeah, Florida, 33012

  • Burke Pharmaceutical Research

    Hot Springs, Arkansas, 71913

  • West Houston Dermatology, PA

    Houston, Texas, 77082

  • Lone Star Children's Medical PLLC

    Houston, Texas, 77092

  • Edmund Lee

    Huntington, New York, 11743

  • Ruth A Yates

    Huntsville, Alabama, 35801

  • Tsu-Yi Chuang

    Indianapolis, Indiana, 46202

  • Dawes Fretzin Clinical Research Group, LLC

    Indianapolis, Indiana, 46256

  • Dermatology and Laser Center

    Irving, Texas, 75061

  • North Florida Dermatology Associates, P.A.

    Jacksonville, Florida, 32204

  • Coastal Dermatology, PA

    Jacksonville, Florida, 32246

  • Jeffrey P Schachne

    Jefferson Valley, New York, 10535

  • Clinical Partners, LLC

    Johnston, Rhode Island, 02919

  • A Center for Dermatology, Cosmetic and Laser Surgery

    Jupiter, Florida, 33458

  • Andrew Berg

    Kansas City, Missouri, 64114-4846

  • Dermatology Associates of Kingsport, PC

    Kingsport, Tennessee, 37660

  • Steven J. Smith, MD

    Kingwood, Texas, 77339

  • Dermatology Associates of Knoxville, PC

    Knoxville, Tennessee, 37922

  • Scripps Clinic

    La Mesa, California, 91941

  • Dermatology Associates of LaGrange

    LaGrange Highlands, Illinois, 60525

  • Allergy, Asthma & Dermatology Research Centers, LLC

    Lake Oswego, Oregon, 97035

  • Dermatology Associates of Lancaster

    Lancaster, Pennsylvania, 17601

  • Stephanie Mackey

    Lancaster, Pennsylvania, 17602

  • Johnnie M Woodson

    Las Vegas, Nevada, 89128

  • Study site

    Las Vegas, Nevada, 89128

  • Robert B. Stromling, MD

    Las Vegas, Nevada, 89144

  • Little Rock Dermatology Clinic

    Little Rock, Arkansas, 72205

  • Livonia Dermatology, PLLC

    Livonia, Michigan, 48154

  • Fairmont Dermatology

    Lodi, California, 95242

  • Rocky Mountain Dermatology

    Logan, Utah, 84341

  • Mark S Wallis

    Longview, Texas, 75604

  • Lubbock Dermatology and Skin Cancer Center

    Lubbock, Texas, 79410

  • Dermatology of East Texas

    Lufkin, Texas, 75904

  • Atlantic Dermatologic Associates, LLC

    Lynbrook, New York, 11563

  • Dermatologic Surgery Specialist Inc.

    Macon, Georgia, 31217

  • Mark Lewis

    Marblehead, Massachusetts, 01945

  • Delta Medical Ctr.

    Memphis, Tennessee, 38120

  • Mobile Dermatology

    Mobile, Alabama, 36609

  • Orange Dermatology Assoc, PC

    Monroe, New York, 10950

  • Allegheny Dermatology Assoc., PC

    Monroeville, Pennsylvania, 15146

  • California Skin Institute

    Mountain View, California, 94040

  • Lesly S. Davidson MD PA

    Mt. Pleasant, South Carolina, 29464

  • Grand Strand Dermatology, LLC

    Myrtle Beach, South Carolina, 29588

  • Saltzer Medical Group, PA

    Nampa, Idaho, 83687

  • Associates in Medical and Surgical Dermatology

    Naples, Florida, 34109

  • Nashua Dermatology Associates

    Nashua, New Hampshire, 03062

  • Abigail James, NP, MSN

    Nashville, Tennessee, 37205

  • Tennessee Clinical Research Center

    Nashville, Tennessee, 37215

  • Jay A. Goldstein, MD

    Natick, Massachusetts, 01760

  • Peter S. Halperin's Office

    New York, New York, 10021

  • Panzer Dermatology Assoc.

    Newark, Delaware, 19713

  • East Penn Dermatology

    North Wales, Pennsylvania, 19454

  • Bender and Kolenik MD, PC

    Norwalk, Connecticut, 06851

  • Charles Halasz

    Norwalk, Connecticut, 06851

  • Stuart Bender

    Norwalk, Connecticut, 06851

  • Dermatology & Laser Center

    Orange Park, Florida, 32073

  • Hillcrest Dermatology Center, PA

    Orangeburg, South Carolina, 29118

  • Peter Accetta

    Orchard Park, New York, 14127

  • Aspen Clinical Research, LLC

    Orem, Utah, 84058

  • Reflections Dermatology & Center for Skin Care

    Orlando, Florida, 32814

  • John L. Meisenheimer, MD

    Orlando, Florida, 32819

  • Advanced Dermatology

    Orlando, Florida, 32828

  • Ormond Beach Dermatology

    Ormond Beach, Florida, 32174

  • Waters Edge Dermatology

    Palm Beach Gardens, Florida, 33410

  • Mark Cheiken

    Palm Coast, Florida, 32137

  • Timothy Kelly, MD, PA

    Palm Harbor, Florida, 34684

  • Ashkan Ghorbani

    Pasadena, Texas, 77504

  • Paul T. Zaydon MD

    Pawtucket, Rhode Island, 02861

  • Snyder & Le M.D. PA

    Pembroke Pines, Florida, 33028

  • Kevin L Welch

    Pensacola, Florida, 32514

  • Soderstrom Dermatology Center

    Peoria, Illinois, 61614

  • David Coynik

    Peru, Illinois, 61354

  • Paddington Testing Co, Inc.

    Philadelphia, Pennsylvania, 19103

  • English Dermatology Centers

    Phoenix, Arizona, 85044

  • Louis H. Martone, MD, PC

    Pittsburgh, Pennsylvania, 15215

  • Neil M. Niren MD

    Pittsburgh, Pennsylvania, 15237

  • Dermatology Associates of Plymouth Meeting- P.C.

    Plymouth Meeting, Pennsylvania, 19462

  • Hecker Dermatology Group PA

    Pompano Beach, Florida, 33064

  • Kenneth M. Reed, MD

    Quincy, Massachusetts, 02169

  • Andrus & Associates Dermatology, PA

    Raleigh, North Carolina, 27609

  • Aylesworth Dermatology SC

    Rhinelander, Wisconsin, 54501

  • Georgia A Seely

    Richmond, Virginia, 23225

  • North Bergen Dermatologic Group

    Ridgewood, New Jersey, 07450

  • Dermatology Partners of Western New York

    Rochester, New York, 14607

  • Greater Washington Dermatology P.A.

    Rockville, Maryland, 20850

  • Todd Colonna

    Rockville, Maryland, 20850

  • Gregory W Thompson

    San Antonio, Texas, 78232

  • Clinical Research Specialists, Inc.

    Santa Monica, California, 90404

  • Schaumburg Dermatology

    Schaumburg, Illinois, 60194

  • Scottsdale Dermatology

    Scottsdale, Arizona, 85251

  • Dermatology Associates, PLLC

    Seattle, Washington, 98101

  • James Hu MD PC

    Seattle, Washington, 98104

  • Joseph Bikowski

    Sewickley, Pennsylvania, 15143

  • American Dermatology Associates

    Shawnee, Kansas, 66216

  • Alan E. Lasser MD PC

    Skokie, Illinois, 60077

  • Dermatique Dermedy Dermatology- PC

    Smithtown, New York, 11787

  • Marina I Peredo, MD

    Smithtown, New York, 11787

  • Four Seasons Dermatology

    South Burlington, Vermont, 05403

  • DeVore Dermatology, PA

    Spartanburg, South Carolina, 29307

  • Ronald S. Nadel

    Springfield, Massachusetts, 01107

  • Eric Olson

    Springfield, Oregon, 97477

  • Sharon K Tiefenbrunn

    St Louis, Missouri, 63109

  • Josiane Lederman, MD, PC

    Staten Island, New York, 10314

  • Judith Andreano

    Strongsville, Ohio, 44136

  • Joseph D. Sutton, MD

    Suffern, New York, 10901

  • Harvey L. Handler, MD

    Sylvania, Ohio, 43560

  • James M. Komorous MD PS

    Tacoma, Washington, 98405

  • Michael A. Scannon MD, PA

    Tampa, Florida, 33607

  • Luis T. Menendez, MD, PA

    Tampa, Florida, 33609

  • Susan E. Katz MD

    The Bronx, New York, 10461

  • Medical College of Ohio

    Toledo, Ohio, 43614

  • Kansas Medical Clinic, PA

    Topeka, Kansas, 66614

  • Somerset Skin Centre

    Troy, Michigan, 48084

  • Paul Klas

    Tualatin, Oregon, 97062

  • Sheftel & Associates Dermatology

    Tucson, Arizona, 85718

  • Options Health Research

    Tulsa, Oklahoma, 74104

  • Dermatology Research Associates of Tyler

    Tyler, Texas, 75703

  • Timothy Abrahamson

    Urbandale, Iowa, 50323

  • Martin Morell, MD

    Utica, New York, 13502

  • Stanley A. Newfield

    Valley Stream, New York, 11581

  • Neil S. Heskel, MD

    Vero Beach, Florida, 32960

  • Sunnycoast Dermatology

    Vero Beach, Florida, 32960

  • Virginia Beach Dermatology Associates, PPLC

    Virginia Beach, Virginia, 23464

  • Eastern Washington Dermatology

    Walla Walla, Washington, 99362

  • Midwest Center for Dermatology and Cosmetic Surgery

    Warren, Michigan, 48093

  • Joel Seigel- MD

    Washington, Pennsylvania, 15301

  • Jeffrey Alter

    Waterbury, Connecticut, 06708

  • Michael T. Siegel MD- P.C.

    Waterford, Michigan, 48328

  • Dermatology Associates

    Waterloo, Iowa, 50702

  • Eileen Ringel

    Waterville, Maine, 04901

  • Palmetto Dermatology, PA

    West Columbia, South Carolina, 29169

  • Paul Getz

    West Dundee, Illinois, 60118

  • Randall Dermatology

    West Lafayette, Indiana, 47906

  • Alan B Schliftman

    White Plains, New York, 10604

  • Moeller Dermatology, LLC

    Wichita, Kansas, 67206

  • Sabrina Dowd

    Williamsport, Pennsylvania, 17701

  • Colleen Demers

    Williamsville, New York, 14221

  • Lynn A. Amarante, MD PC

    Williamsville, New York, 14221

  • Atlantic Skin and Cosmetic Surgery- P.C.

    Wilmington, Delaware, 19810

  • Atlantic Dermatology Associates, P.A.

    Wilmington, North Carolina, 28401

  • WHA Medical Clinic PLLC

    Wilmington, North Carolina, 28401

Other trials in United States

Canada27 sites
  • Clinique de dermatologie Dr. Francois Bouchard

    Alma, Quebec, G8B 2V5

  • Francoise Giard

    Gatineau, Quebec, J8T 7W3

  • Sudbury Skin Clinic

    Greater Sudbury, Ontario, P3E 5M4

  • Dermatrials Research

    Hamilton, Ontario, L8N 1V6

  • Limestone Dermatology & Laser Clinic

    Kingston, Ontario, K7L 1S2

  • Mediprobe Research, Inc.

    London, Ontario, N5X 2P1

  • The Guenther Dermatology Research Centre

    London, Ontario, N6A 3H7

  • Wellington Dermatology Associates

    London, Ontario, N6H 1S9

  • Lynderm Research, Inc.

    Markham, Ontario, L3P 1A8

  • Innovaderm Research, Inc

    Montreal, Quebec, H2K 4L5

  • Siena Medical Research

    Montreal, Quebec, H3Z 2S6

  • John J. Turner, MD

    Newmarket, Ontario, L3Y 5G8

  • A.M. Katz Medicine D.C.

    Newmarket, Ontario, L3Y 6P5

  • Dermatology Clinic

    North York, Ontario, M3K 1Z1

  • Skin Centre for Dermatology

    Peterborough, Ontario, K9J 1Z2

  • Giles P. Raymond

    Pierrefonds, Quebec, H8Z 1W5

  • CRCMR Gilbert Inc.

    Québec, Quebec, G1J 1X7

  • (CRDQ) Centre De Recherche Dermatologique Du Quebec Metropolitan

    Québec, Quebec, G1V 4X7

  • Douglas N. Keeling MD Dermatologist PC

    Quispamsis, New Brunswick, E2E 4Z4

  • Victoria East Medical Clinic

    Regina, Saskatchewan, S4V 3A6

  • Nexus Clinical Research

    St. John's, Newfoundland and Labrador, A1A 5E8

  • Study site

    St. John's, Newfoundland and Labrador, A1B 3E1

  • NewLab Clinical Research, Inc.

    St. John's, Newfoundland and Labrador, A1C 2H5

  • Dermatology Associates

    Toronto, Ontario, M3H 3S3

  • Specialized Dermatology

    Welland, Ontario, L3C 3W4

  • Winnipeg Clinic

    Winnepeg, Manitoba, R3C 0N2

  • Dermadvances Research

    Winnipeg, Manitoba, R3C 1R4

Other trials in Canada

About this study

Official title: Assessment and Tracking of Long-term Alefacept (LFA-3/IgG1 Fusion Protein) Safety (ATLAS)

Subjects exposed to alefacept are to be enrolled. Subjects will be contacted every 6 months to gather general health information.

Read the detailed description

There are no study-mandated tests, visits or clinical interventions after the 1st (enrolling) visit. After the patient is enrolled in the study, they will be contacted every 6 months to complete structured telephone interviews conducted by the ATLAS Study Center.

Conditions
Psoriasis
Being tested
Alefacept exposure
Keywords
Psoriasis, Alefacept, Amevive®, Drug exposure
Medical subject headings
Psoriasis

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Alefacept exposureDrug

    Also called Amevive, ASP0485

    Observational

Study groups in NCT00454701
Study groupRoleWhat they receive
1. Amevive ExposurePatients treated with alefacept for chronic plaque psoriasis
Receives: Drug: Alefacept exposure

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. To measure the rates of non-Hodgkin's lymphoma (NHL) and infections that require hospitalization occurring in psoriasis patients treated with alefacept

    Measured: At six month intervals for five years

Secondary outcomes (1)
  1. To estimate the rates of lung cancer, breast cancer (female), prostate cancer, colorectal cancer, melanoma and active tuberculosis within a population of patients with psoriasis treated with alefacept.

    Measured: At six month intervals for five years

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted2 Apr 2007 (estimated)
  2. Study startJun 2003
  3. Primary completionFeb 2012
  4. Study completionFeb 2012

Why it stopped: The Sponsor has made a decision, driven by business needs, to cease promotion, manufacturing, distribution and sales of Amevive

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
1,897 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT00454701
Sponsor's protocol ID
0485-CL-0001
Other IDs
C-736
Acronym
ATLAS
Status last verified
Dec 2013
First submitted
29 Mar 2007
Last updated
11 Dec 2013
Results posted
No
Data monitoring committee
Yes

Questions about this trial

What is this clinical trial studying?

An observational study of Psoriasis, run by Astellas Pharma Inc at 268 sites in 2 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: stopped early, as of the sponsor's last update on 11 Dec 2013. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 268 sites in United States, Canada. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study was stopped early (reason given: The Sponsor has made a decision, driven by business needs, to cease promotion, manufacturing, distribution and sales of Amevive). Results are not available in the source record.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

To measure the rates of non-Hodgkin's lymphoma (NHL) and infections that require hospitalization occurring in psoriasis patients treated with alefacept (time frame: At six month intervals for five years). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Dec 2013.

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