Endometrial CancerNCT00514254
Risk Factors for Endometrial Cancer in Black Women
An observational study of Endometrial Cancer, run by Memorial Sloan Kettering Cancer Center at 4 sites in United States.
Trial summary
RATIONALE: Learning about the risk factors for endometrial cancer in black women may help the study of endometrial cancer in the future. PURPOSE: This clinical trial is studying risk factors for endometrial cancer in black women. Read more about this study
- Who is it for?
- Ages 21 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Endometrial Cancer
- What is being tested?
- questionnaire administration, study of socioeconomic and demographic variables and evaluation of cancer risk factors
- Type of treatment
- Surgery or procedure
- How many people
- 59 participants
- Where
- 4 sitesUnited States
- Study dates
- Jul 2007to Jul 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 years and older
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: Black women (including African-American, African, Afro-Caribbean women) with endometrial cancer and controls will be recruited at MSKCC, SUNY Downstate Medical Center and Montefiore Medical Center hospitals. Controls will be black (including African-American, African, Afro-Caribbean) women without history of cancer, who have intact uteri, and will be identified in gynecology clinics. Controls will also be recruited at the Breast Examination Center of Harlem (BECH), an affiliate of MSKCC, providing high quality screening services to a minority community.
DISEASE CHARACTERISTICS:
- Cases
- Diagnosed with endometrial cancer within the past year
- Self-identified as being black, African-American, black Hispanic, African, or Afro-Caribbean
- Healthy controls
- Self-identified as being black, African-American, black Hispanic, African, or Afro-Caribbean
- No history of endometrial or other cancer (except non-melanoma skin cancer)
- No prior hysterectomy
PATIENT CHARACTERISTICS:
- Speak English
- No medical condition that would make it difficult to complete the interview
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Trial locations and contacts
4 sites in 1 country.
United States4 sites
SUNY Downstate Medical Center
Brooklyn, New York, 11203
City College of New York
New York, New York, 10031
Memorial Sloan Kettering Cancer Center
New York, New York, 10065
Montefiore Medical Center
The Bronx, New York, 10461
About this study
Official title: Endometrial Cancer in Black Women
RATIONALE: Learning about the risk factors for endometrial cancer in black women may help the study of endometrial cancer in the future.
PURPOSE: This clinical trial is studying risk factors for endometrial cancer in black women.
Read the detailed description
OBJECTIVES:
- Establish and evaluate procedures for conducting a hospital-based case-control study of risk factors for endometrial cancer in black women.
OUTLINE: This is a multicenter study.
Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research.
PROJECTED ACCRUAL:
- A total of 30 cases and 30 controls will be accrued for this study.
- Conditions
- Endometrial Cancer
- Being tested
- questionnaire administration, study of socioeconomic and demographic variables, evaluation of cancer risk factors
- Keywords
- endometrial cancer, risk factors, questionnaire, 07-093
- Medical subject headings
- Endometrial Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
questionnaire administrationOther
study of socioeconomic and demographic variablesOther
evaluation of cancer risk factorsProcedure or surgery
| Study group | Role | What they receive |
|---|---|---|
| case | Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. Receives: Other: questionnaire administration; Other: study of socioeconomic and demographic variables; Procedure: evaluation of cancer risk factors | |
| control | Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. Receives: Other: questionnaire administration; Other: study of socioeconomic and demographic variables; Procedure: evaluation of cancer risk factors |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number and percentage of potential cases and controls approached who are found to be eligible for the study and reasons for being ineligible (including language)
Measured: 2 years
Number and percentage of cases and controls approached who sign informed consent
Measured: 2 years
Number and percentage of cases and controls who complete each part of the study (main questionnaire, diet questionnaire, saliva/buccal specimen)
Measured: 2 years
Proportion of questions with missing data
Measured: 2 years
Interviewer's evaluation of interview quality and respondent cooperation
Measured: 2 years
Number and percentage of cases who are willing to have tumor specimens used for future research
Measured: 2 years
Characteristics of cases and controls (demographics, main risk factors, and use of health care and screening)
Measured: 2 years
Proportion of participants who rate the study positively on each measure in the post-interview assessment and respondents' suggested changes to the study
Measured: 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Aug 2007 (estimated)
- Study startJul 2007
- Primary completionJul 2027 (estimated)
- Study completionJul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Endometrial CancerStudies of the same condition, open and under way.
- More trials run by Memorial Sloan Kettering Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 59 participants (actual)
Sponsor and investigators
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI), The City College of New York, DOWNSTATE MED/KINGS CO/BKLYN, Montefiore Medical Center
- Responsible party
- Sponsor
- Investigators
- Sara Olson, PhD, Principal investigator, Memorial Sloan Kettering Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00514254
- Sponsor's protocol ID
- 07-093
- Other IDs
- P30CA008748, MSKCC-07093
- Status last verified
- Aug 2026
- First submitted
- 8 Aug 2007
- Last updated
- 13 Aug 2026
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Endometrial Cancer in Black Women
- ClinicalTrials.gov ID
- NCT00514254
- Acronym / sponsor ID
- 07-093
- Conditions
- Endometrial Cancer
- Keywords
- endometrial cancer, risk factors, questionnaire, 07-093
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 59 participants (actual)
- Lead sponsor
- Memorial Sloan Kettering Cancer CenterUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI), The City College of New York, DOWNSTATE MED/KINGS CO/BKLYN, Montefiore Medical Center
- Study start
- Jul 2007
- Primary completion
- Jul 2027 (estimated)
- Study completion
- Jul 2027 (estimated)
- First posted
- 9 Aug 2007 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
RATIONALE: Learning about the risk factors for endometrial cancer in black women may help the study of endometrial cancer in the future.
PURPOSE: This clinical trial is studying risk factors for endometrial cancer in black women.
Detailed description
OBJECTIVES:
- Establish and evaluate procedures for conducting a hospital-based case-control study of risk factors for endometrial cancer in black women.
OUTLINE: This is a multicenter study.
Participants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research.
PROJECTED ACCRUAL:
- A total of 30 cases and 30 controls will be accrued for this study.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| case | – | Other: questionnaire administration, Other: study of socioeconomic and demographic variables, Procedure: evaluation of cancer risk factorsParticipants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. |
| control | – | Other: questionnaire administration, Other: study of socioeconomic and demographic variables, Procedure: evaluation of cancer risk factorsParticipants complete questionnaires about lifestyle factors and their usual diet and measure their waist and hips. Saliva or buccal specimens are collected for future research. |
Who may qualify
- Ages
- 21 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Black women (including African-American, African, Afro-Caribbean women) with endometrial cancer and controls will be recruited at MSKCC, SUNY Downstate Medical Center and Montefiore Medical Center hospitals. Controls will be black (including African-American, African, Afro-Caribbean) women without history of cancer, who have intact uteri, and will be identified in gynecology clinics. Controls will also be recruited at the Breast Examination Center of Harlem (BECH), an affiliate of MSKCC, providing high quality screening services to a minority community.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| questionnaire administration | Other | case, control |
| study of socioeconomic and demographic variables | Other | case, control |
| evaluation of cancer risk factors | Procedure or surgery | case, control |
Primary outcome
Number and percentage of potential cases and controls approached who are found to be eligible for the study and reasons for being ineligible (including language)
Time frame: 2 years
Number and percentage of cases and controls approached who sign informed consent
Time frame: 2 years
Number and percentage of cases and controls who complete each part of the study (main questionnaire, diet questionnaire, saliva/buccal specimen)
Time frame: 2 years
Proportion of questions with missing data
Time frame: 2 years
Interviewer's evaluation of interview quality and respondent cooperation
Time frame: 2 years
Number and percentage of cases who are willing to have tumor specimens used for future research
Time frame: 2 years
Characteristics of cases and controls (demographics, main risk factors, and use of health care and screening)
Time frame: 2 years
Proportion of participants who rate the study positively on each measure in the post-interview assessment and respondents' suggested changes to the study
Time frame: 2 years
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Aug 2026.
- Memorial Sloan Kettering Cancer CenterLink provided by the sponsor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Sara Olson, PhD principal investigator
Memorial Sloan Kettering Cancer Center
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Endometrial Cancer, run by Memorial Sloan Kettering Cancer Center at 4 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 13 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number and percentage of potential cases and controls approached who are found to be eligible for the study and reasons for being ineligible (including language) (time frame: 2 years). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Aug 2026.