Smoking CessationNCT00591175
A Randomized Clinical Trial Assessing Smoking Cessation Interventions In Dental Clinic Smokers
An observational study of Smoking Cessation, run by Memorial Sloan Kettering Cancer Center at 1 site in United States.
Trial summary
The goal of this study is to see if giving patients information about how smoking affects oral health will help them quit smoking. What we learn from this study will help researchers find new ways to help smokers. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Smoking Cessation
- What is being tested?
- Dental Hygienist provided counseling + Brief Questionnaire and Dental Hygienist provided counseling with personalized risk communication + Brief Questionnaire
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 1,072 participants
- Where
- 1 siteUnited States
- Study dates
- Dec 2001to Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Smokers who are also patients at the NYU College of Dentistry
Who may be able to join
- Patient seeking routine dental care at NYU College of Dentistry and meets medical clearance for routine care
- Active smokers (active smoking as self-reported regular use of at least 10 cigarettes per day)
- Able to provide a telephone number or collateral contact information where they can be reached over the subsequent 12 months
- Fluent in English or Spanish
Who cannot join
- History of mouth or throat cancer
Trial locations and contacts
1 site in 1 country.
United States1 site
Memorial Sloan Kettering Cancer Center
New York, New York, 10065
About this study
The goal of this study is to see if giving patients information about how smoking affects oral health will help them quit smoking. What we learn from this study will help researchers find new ways to help smokers.
- Conditions
- Smoking Cessation
- Being tested
- Standard Care only, Dental Hygienist provided counseling + Brief Questionnaire, Dental Hygienist provided counseling with personalized risk communication + Brief Questionnaire
- Medical subject headings
- Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Standard Care onlyBehavioural
Dentist Provided Standard Care, 3-month follow-up assessment, Clinic visit salivary cotinine test, 12-month follow-up assessment, Clinic visit salivary cotinine test
Dental Hygienist provided counseling + Brief QuestionnaireBehavioural
Dental Hygienist provided + Brief Questionnaire, 3-month follow-up assessment,Clinic visit salivary cotinine test, 12-month follow-up, Clinic visit salivary cotinine test assessment
Dental Hygienist provided counseling with personalized risk communication + Brief QuestionnaireBehavioural
Dental Hygienist provided counseling with personalized risk communication + Brief Questionnaire, 3-month follow-up assessment, Clinic visit salivary cotinine test, 12-month follow-up assessment, Clinic visit salivary cotinine test
| Study group | Role | What they receive |
|---|---|---|
| 1 | Standard Care Receives: Behavioral: Standard Care only | |
| 2 | Standard Care with Hygienist Counseling Receives: Behavioral: Dental Hygienist provided counseling + Brief Questionnaire | |
| 3 | Standard Care with Hygienist Counseling \& Personalized Risk Communication Receives: Behavioral: Dental Hygienist provided counseling with personalized risk communication + Brief Questionnaire |
What is being measured
The primary outcome is the main question the study is designed to answer.
efficacy of varied smoking cessation interventions
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jan 2008 (estimated)
- Study startDec 2001
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Smoking CessationStudies of the same condition, open and under way.
- More trials run by Memorial Sloan Kettering Cancer CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,072 participants (actual)
Sponsor and investigators
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Sponsor type
- University, hospital or other
- Collaborators
- NYU College of Dentistry
- Responsible party
- Sponsor
- Investigators
- Jamie Ostroff, PhD, Principal investigator, Memorial Sloan Kettering Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00591175
- Sponsor's protocol ID
- 01-117
- Status last verified
- Jan 2026
- First submitted
- 26 Dec 2007
- Last updated
- 7 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
Publications
Holliday R, Hong B, McColl E, Livingstone-Banks J, Preshaw PM. Interventions for tobacco cessation delivered by dental professionals. Cochrane Database Syst Rev. 2021 Feb 19;2(2):CD005084. doi: 10.1002/14651858.CD005084.pub4.
PubMed 33605440
Study at a glance
From the registry record, last updated by the sponsor on 7 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized Clinical Trial Assessing Smoking Cessation Interventions In Dental Clinic Smokers
- ClinicalTrials.gov ID
- NCT00591175
- Acronym / sponsor ID
- 01-117
- Conditions
- Smoking Cessation
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 1,072 participants (actual)
- Lead sponsor
- Memorial Sloan Kettering Cancer CenterUniversity, hospital or other
- Collaborators
- NYU College of Dentistry
- Study start
- Dec 2001
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 11 Jan 2008 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to see if giving patients information about how smoking affects oral health will help them quit smoking. What we learn from this study will help researchers find new ways to help smokers.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| 1 | – | Behavioral: Standard Care onlyStandard Care |
| 2 | – | Behavioral: Dental Hygienist provided counseling + Brief QuestionnaireStandard Care with Hygienist Counseling |
| 3 | – | Behavioral: Dental Hygienist provided counseling with personalized risk communication + Brief QuestionnaireStandard Care with Hygienist Counseling \& Personalized Risk Communication |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Smokers who are also patients at the NYU College of Dentistry
Key inclusion criteria (4 listed)
- Patient seeking routine dental care at NYU College of Dentistry and meets medical clearance for routine care
- Active smokers (active smoking as self-reported regular use of at least 10 cigarettes per day)
- Able to provide a telephone number or collateral contact information where they can be reached over the subsequent 12 months
- Fluent in English or Spanish
Key exclusion criteria (1 listed)
- History of mouth or throat cancer
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Standard Care onlyDentist Provided Standard Care, 3-month follow-up assessment, Clinic visit salivary cotinine test, 12-month follow-up assessment, Clinic visit salivary cotinine test | Behavioural | 1 |
| Dental Hygienist provided counseling + Brief QuestionnaireDental Hygienist provided + Brief Questionnaire, 3-month follow-up assessment,Clinic visit salivary cotinine test, 12-month follow-up, Clinic visit salivary cotinine test assessment | Behavioural | 2 |
| Dental Hygienist provided counseling with personalized risk communication + Brief QuestionnaireDental Hygienist provided counseling with personalized risk communication + Brief Questionnaire, 3-month follow-up assessment, Clinic visit salivary cotinine test, 12-month follow-up assessment, Clinic visit salivary cotinine test | Behavioural | 3 |
Primary outcome
efficacy of varied smoking cessation interventions
Time frame: 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jan 2026.
- Derived from this study: PubMed 33605440Holliday R, Hong B, McColl E, Livingstone-Banks J, Preshaw PM. Interventions for tobacco cessation delivered by dental professionals. Cochrane Database Syst Rev. 2021 Feb 19;2(2):CD005084. doi: 10.1002/14651858.CD005084.pub4.
- Memorial Sloan-Kettering Cancer CenterLink provided by the sponsor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Jamie Ostroff, PhD principal investigator
Memorial Sloan Kettering Cancer Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Smoking Cessation, run by Memorial Sloan Kettering Cancer Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 7 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
efficacy of varied smoking cessation interventions (time frame: 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00591175, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jan 2026.