HealthyNCT00673998
Isokinetic Testing Protocol in Elderly and Young Men
A study testing Isokinetic Dynamometer (Biodex system III) in people with Healthy, run by University of Brasilia at 1 site in Brazil.
Trial summary
An age-related decrease in muscular strength may have a detrimental effect on muscle fatigue and recovery. To date, only one study has determined the effect of varied rest intervals (RI) between exercise sets in active younger and older women. Read more about this study
- Who is it for?
- Ages 20 to 75 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Isokinetic Dynamometer (Biodex system III)
- Type of treatment
- Medical device
- How many people
- 38 participants
- Where
- 1 siteBrazil
- Study dates
- Feb 2005to Nov 2006
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 75 years
- Men only
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Less than 75 years
- Independent
Who cannot join
- History of cardiovascular disease
- Hypertension
- Orthopedic disease
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effects of Rest Interval on Quadriceps Torque During an Isokinetic Testing Protocol in Elderly and Young Men
An age-related decrease in muscular strength may have a detrimental effect on muscle fatigue and recovery. To date, only one study has determined the effect of varied rest intervals (RI) between exercise sets in active younger and older women. They reported that active younger and older women require similar RI between sets to recovery full isokinetic knee extension peak torque (PT). However, we are unaware of any published studies comparing RI PT recovery between younger and older men. Thus, the purpose of this study was to compare the effect of two different RI's between sets of isokinetic knee extension exercise on PT, and Total Work (TW) between untrained younger and older men.
Read the detailed description
18 young men (24.22 ± 2.58 yrs) and 20 older men (66.85 ± 4.02 yrs) performed 3 sets of 10 unilateral isokinetic knee extension repetitions at 60°/s. The rest intervals between sets were 1 and 2 minutes and were counterbalanced across 2 testing days, separated by a minimum of 48 hours. The work-to-rest ratio was 1:3 and 1:6. All subjects were not involved in exercise programs that included resistance exercises within the last 6 months. Statistical evaluation of the data was performed using a 2x 2 x 3 mixed factor repeated measures ANOVA [age (younger and older) x rest interval (1 and 2 min) x set (1st, 2nd, and 3rd)]. Statistical significance was set at p < 0.05 for all comparisons.
- Conditions
- Healthy
- Being tested
- Isokinetic Dynamometer (Biodex system III)
- Keywords
- Isokinetic, Fatigue, Strength, Older
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Isokinetic Dynamometer (Biodex system III)Device
Also called Biodex Isokinetic Dynamometer, Cybex Isokinetic Dynamometer
Biodex system III Isokinetic Dynamometer (Biodex Medical, Inc., Shirley, NY).
What is being measured
The primary outcome is the main question the study is designed to answer.
Peak Torque
Measured: 1 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2008 (estimated)
- Study startFeb 2005
- Primary completionMar 2006
- Study completionNov 2006
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 38 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Brasilia
- Sponsor type
- University, hospital or other
- Investigators
- Martim Bottaro, PhD, Principal investigator, University of Brasilia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00673998
- Sponsor's protocol ID
- UCB-072/2004
- Status last verified
- May 2008
- First submitted
- 30 Apr 2008
- Last updated
- 7 May 2008
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 May 2008. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Rest Interval on Quadriceps Torque During an Isokinetic Testing Protocol in Elderly and Young Men
- ClinicalTrials.gov ID
- NCT00673998
- Acronym / sponsor ID
- UCB-072/2004
- Conditions
- Healthy
- Keywords
- Isokinetic, Fatigue, Strength, Older
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 38 participants (actual)
- Lead sponsor
- University of BrasiliaUniversity, hospital or other
- Study start
- Feb 2005
- Primary completion
- Mar 2006 (actual)
- Study completion
- Nov 2006 (actual)
- First posted
- 7 May 2008 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
An age-related decrease in muscular strength may have a detrimental effect on muscle fatigue and recovery. To date, only one study has determined the effect of varied rest intervals (RI) between exercise sets in active younger and older women. They reported that active younger and older women require similar RI between sets to recovery full isokinetic knee extension peak torque (PT). However, we are unaware of any published studies comparing RI PT recovery between younger and older men. Thus, the purpose of this study was to compare the effect of two different RI's between sets of isokinetic knee extension exercise on PT, and Total Work (TW) between untrained younger and older men.
Detailed description
18 young men (24.22 ± 2.58 yrs) and 20 older men (66.85 ± 4.02 yrs) performed 3 sets of 10 unilateral isokinetic knee extension repetitions at 60°/s. The rest intervals between sets were 1 and 2 minutes and were counterbalanced across 2 testing days, separated by a minimum of 48 hours. The work-to-rest ratio was 1:3 and 1:6. All subjects were not involved in exercise programs that included resistance exercises within the last 6 months. Statistical evaluation of the data was performed using a 2x 2 x 3 mixed factor repeated measures ANOVA [age (younger and older) x rest interval (1 and 2 min) x set (1st, 2nd, and 3rd)]. Statistical significance was set at p < 0.05 for all comparisons.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
Who may qualify
- Ages
- 20 to 75 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Less than 75 years
- Independent
Key exclusion criteria (3 listed)
- History of cardiovascular disease
- Hypertension
- Orthopedic disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Isokinetic Dynamometer (Biodex system III)Also: Biodex Isokinetic Dynamometer, Cybex Isokinetic DynamometerBiodex system III Isokinetic Dynamometer (Biodex Medical, Inc., Shirley, NY). | Device | – |
Primary outcome
Peak Torque
Time frame: 1 week
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 May 2008.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Martim Bottaro, PhD principal investigator
University of Brasilia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Isokinetic Dynamometer (Biodex system III) in people with Healthy, run by University of Brasilia at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 May 2008. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Peak Torque (time frame: 1 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 May 2008.