Asthmacold airNCT00686491
Respiratory Health of Elite Athletes
An observational study of Asthma and Cardiovascular Diseases, run by Laval University at 1 site in Canada.
Trial summary
Eleven National Sports Teams are located in the Quebec Metropolitan Area. In these groups, many athletes are aiming for Olympic medals in Beijing 2008 and Vancouver 2010 Olympic Games. Read more about this study
- Who is it for?
- Ages 14 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Asthma, Cardiovascular Diseases, Metabolic Diseases
- How many people
- 133 participants
- Where
- 1 siteCanada
- Study dates
- Jun 2007to Dec 2010
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 45 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Study population: Athletes training in the province of Quebec. Controls from Quebec schools and universities.
Who may be able to join
- Athletes training more than 10 hours per week-
Who cannot join
- asthma or other pathologies that may interfere with the study
- Smokers
- Obese of with a BMI more than 29
Trial locations and contacts
1 site in 1 country.
Canada1 site
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Québec, Quebec, G1V4G5
About this study
Official title: Center of Excellence in CardioRespiratory Health of High-level Athletes: Evaluation of Long-term Effects of Training.
Eleven National Sports Teams are located in the Quebec Metropolitan Area. In these groups, many athletes are aiming for Olympic medals in Beijing 2008 and Vancouver 2010 Olympic Games. A consultation of the coaches of these National Teams revealed that although a large proportion of these athletes present various cardio-respiratory symptoms, they do not have a rapid access to a systematic medical evaluation and follow-up. Furthermore, little is done in regard to prevention and optimization of treatment of pulmonary and cardiac conditions in the elite athlete's population of the Quebec area.
Cardiorespiratory problems are therefore commonly found in high-level athletes. However, these pathologies are not well characterized in athletes and the associated symptoms often not well perceived. These problems can be serious and it is important to detect them before they appear1 while setting up a systematic medical follow-up. Health professionals should monitor health of the young athletes and help to reduce the risks associated with high level exercise. The following project is an evaluation and follow-up program of high-level athletes, aiming at gathering key-information on long-term effects of high-level training on cardio-respiratory and metabolic parameters. Our aims will be
- to establish a long-term program of systematic evaluation and follow-up of cardiorespiratory health and performance of high elite athletes.
- to evaluate the prevalence of respiratory, circulatory and metabolic problems among high-level athletes
- to evaluate the effects of treatments on cardiorespiratory conditions and exercise performance in athletes who need asthma medication.
- Conditions
- Asthma, Cardiovascular Diseases, Metabolic Diseases
- Keywords
- Asthma, Environment, Type of sport, Cardiovascular disease, Athletes
- Medical subject headings
- Asthma, Cardiovascular Diseases, Metabolic Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| 1 | Triathletes | |
| 2 | Cold air athletes | |
| 3 | Swimmers | |
| 4 | Other sports elite athletes | |
| 5 | Control subjects |
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 May 2008 (estimated)
- Study startJun 2007
- Primary completionDec 2010
- Study completionDec 2010
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for AsthmaStudies of the same condition, open and under way.
- More trials run by Laval UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 133 participants (actual)
Sponsor and investigators
- Lead sponsor
- Laval University
- Sponsor type
- University, hospital or other
- Investigators
- Paul POIRIER, MD, Principal investigator, Hôpital LAval
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00686491
- Sponsor's protocol ID
- CER 20141
- Acronym
- cold air
- Status last verified
- Feb 2011
- First submitted
- 26 May 2008
- Last updated
- 23 Feb 2011
- Results posted
- No
- Data monitoring committee
- No
Publications
Bougault V, Blouin E, Turmel J, Boulet LP. Airway response to methacholine following eucapnic voluntary hyperpnea in athletes. PLoS One. 2015 Mar 19;10(3):e0121781. doi: 10.1371/journal.pone.0121781. eCollection 2015.
PubMed 25789614Turmel J, Bougault V, Boulet LP, Poirier P. Exaggerated blood pressure response to exercise in athletes: dysmetabolism or altered autonomic nervous system modulation? Blood Press Monit. 2012 Oct;17(5):184-92. doi: 10.1097/MBP.0b013e3283573509.
PubMed 22828668Bougault V, Turmel J, Boulet LP. Bronchial challenges and respiratory symptoms in elite swimmers and winter sport athletes: Airway hyperresponsiveness in asthma: its measurement and clinical significance. Chest. 2010 Aug;138(2 Suppl):31S-37S. doi: 10.1378/chest.09-1689. Epub 2010 Apr 2.
PubMed 20363843
Study at a glance
From the registry record, last updated by the sponsor on 23 Feb 2011. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Center of Excellence in CardioRespiratory Health of High-level Athletes: Evaluation of Long-term Effects of Training.
- ClinicalTrials.gov ID
- NCT00686491
- Acronym / sponsor ID
- cold air / CER 20141
- Conditions
- Asthma, Cardiovascular Diseases, Metabolic Diseases
- Keywords
- Asthma, Environment, Type of sport, Cardiovascular disease, Athletes
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 133 participants (actual)
- Lead sponsor
- Laval UniversityUniversity, hospital or other
- Study start
- Jun 2007
- Primary completion
- Dec 2010 (actual)
- Study completion
- Dec 2010 (actual)
- First posted
- 29 May 2008 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Eleven National Sports Teams are located in the Quebec Metropolitan Area. In these groups, many athletes are aiming for Olympic medals in Beijing 2008 and Vancouver 2010 Olympic Games. A consultation of the coaches of these National Teams revealed that although a large proportion of these athletes present various cardio-respiratory symptoms, they do not have a rapid access to a systematic medical evaluation and follow-up. Furthermore, little is done in regard to prevention and optimization of treatment of pulmonary and cardiac conditions in the elite athlete's population of the Quebec area.
Cardiorespiratory problems are therefore commonly found in high-level athletes. However, these pathologies are not well characterized in athletes and the associated symptoms often not well perceived. These problems can be serious and it is important to detect them before they appear1 while setting up a systematic medical follow-up. Health professionals should monitor health of the young athletes and help to reduce the risks associated with high level exercise. The following project is an evaluation and follow-up program of high-level athletes, aiming at gathering key-information on long-term effects of high-level training on cardio-respiratory and metabolic parameters. Our aims will be
- to establish a long-term program of systematic evaluation and follow-up of cardiorespiratory health and performance of high elite athletes.
- to evaluate the prevalence of respiratory, circulatory and metabolic problems among high-level athletes
- to evaluate the effects of treatments on cardiorespiratory conditions and exercise performance in athletes who need asthma medication.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| 1 | – | –Triathletes |
| 2 | – | –Cold air athletes |
| 3 | – | –Swimmers |
| 4 | – | –Other sports elite athletes |
| 5 | – | –Control subjects |
Who may qualify
- Ages
- 14 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- Athletes training in the province of Quebec. Controls from Quebec schools and universities.
Key inclusion criteria (1 listed)
- Athletes training more than 10 hours per week-
Key exclusion criteria (3 listed)
- asthma or other pathologies that may interfere with the study
- Smokers
- Obese of with a BMI more than 29
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Feb 2011.
- Derived from this study: PubMed 25789614Bougault V, Blouin E, Turmel J, Boulet LP. Airway response to methacholine following eucapnic voluntary hyperpnea in athletes. PLoS One. 2015 Mar 19;10(3):e0121781. doi: 10.1371/journal.pone.0121781. eCollection 2015.
- Derived from this study: PubMed 22828668Turmel J, Bougault V, Boulet LP, Poirier P. Exaggerated blood pressure response to exercise in athletes: dysmetabolism or altered autonomic nervous system modulation? Blood Press Monit. 2012 Oct;17(5):184-92. doi: 10.1097/MBP.0b013e3283573509.
- Derived from this study: PubMed 20363843Bougault V, Turmel J, Boulet LP. Bronchial challenges and respiratory symptoms in elite swimmers and winter sport athletes: Airway hyperresponsiveness in asthma: its measurement and clinical significance. Chest. 2010 Aug;138(2 Suppl):31S-37S. doi: 10.1378/chest.09-1689. Epub 2010 Apr 2.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Paul POIRIER, MD principal investigator
Hôpital LAval
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Asthma and Cardiovascular Diseases, run by Laval University at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Feb 2011. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00686491, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Feb 2011; AzTrials last refreshed its copy on 7 Nov 2026.