Osteoarthritis, KneeNCT00687726
Simple Home-Based Exercise for Knee Osteoarthritis
A study testing Standing balance exercise and Isometric knee extension exercise in people with Osteoarthritis, Knee, run by Srinakharinwirot University at 1 site in Thailand.
Trial summary
1. Simple home-based standing balance training and isometric knee extension exercise for 4 weeks would improve functional ability and knee muscle strength of patients with knee osteoarthritis. 2. The outcome of standing balance training is different from isometric knee extension exercise. Read more about this study
- Who is it for?
- Ages 50 to 80 years
- Conditions the study is for
- Osteoarthritis, Knee
- What is being tested?
- Standing balance exercise and Isometric knee extension exercise
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 48 participants
- Where
- 1 siteThailand
- Study dates
- May 2006to Feb 2008
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Clinical criteria for knee osteoarthritis
Who cannot join
- cardiovascular disease
- Parkinsonism
- osteoporosis
- inability to walk for 15 meters
- intra-articular injections
Trial locations and contacts
1 site in 1 country.
Thailand1 site
Faculty of Health Science, Srinakharinwirot University
Ongkharak, Changwat Nakhon Nayok, 26120
About this study
Official title: The Relationship of Knee Joint Osteoarthritis to Balance and Walking Ability.
- Simple home-based standing balance training and isometric knee extension exercise for 4 weeks would improve functional ability and knee muscle strength of patients with knee osteoarthritis.
- The outcome of standing balance training is different from isometric knee extension exercise.
- Conditions
- Osteoarthritis, Knee
- Being tested
- Standing balance exercise, Isometric knee extension exercise
- Keywords
- osteoarthritis, knee, exercise, balance
- Medical subject headings
- Osteoarthritis, Knee, Osteoarthritis, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Standing balance exerciseBehavioural
Standing balance and mini squat exercise performed 30 times/day/side, 5 days/week, for 4 weeks.
Isometric knee extension exerciseBehavioural
Isometric knee extension exercise performed 10 repetitions/set, 3 sets/day, 5 days/week for 4 weeks
| Study group | Role | What they receive |
|---|---|---|
| G1 | Experimental | Standing balance and mini squat training Receives: Behavioral: Standing balance exercise |
| G2 | Active comparator | Isometric knee extension exercise Receives: Behavioral: Isometric knee extension exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee osteoarthritis outcome scores (KOOS)
Measured: 4 weeks
Secondary outcomes (2)
Knee muscle peak torque
Measured: 4 weeks
Aggregate functional performance time
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Jun 2008 (estimated)
- Study startMay 2006
- Primary completionAug 2007
- Study completionFeb 2008
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Osteoarthritis, KneeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 48 participants (actual)
Sponsor and investigators
- Lead sponsor
- Srinakharinwirot University
- Sponsor type
- University, hospital or other
- Investigators
- Kanda Chaipinyo, PT,PhD., Principal investigator, Srinakharinwirot University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00687726
- Sponsor's protocol ID
- 056/2547
- Status last verified
- May 2008
- First submitted
- 28 May 2008
- Last updated
- 2 Jun 2008
- Results posted
- No
- Data monitoring committee
- No
Publications
Chaipinyo K, Karoonsupcharoen O. No difference between home-based strength training and home-based balance training on pain in patients with knee osteoarthritis: a randomised trial. Aust J Physiother. 2009;55(1):25-30. doi: 10.1016/s0004-9514(09)70057-1.
PubMed 19226239
Study at a glance
From the registry record, last updated by the sponsor on 2 Jun 2008. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Relationship of Knee Joint Osteoarthritis to Balance and Walking Ability.
- ClinicalTrials.gov ID
- NCT00687726
- Acronym / sponsor ID
- 056/2547
- Conditions
- Osteoarthritis, Knee
- Keywords
- osteoarthritis, knee, exercise, balance
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 48 participants (actual)
- Lead sponsor
- Srinakharinwirot UniversityUniversity, hospital or other
- Study start
- May 2006
- Primary completion
- Aug 2007 (actual)
- Study completion
- Feb 2008 (actual)
- First posted
- 2 Jun 2008 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
- Simple home-based standing balance training and isometric knee extension exercise for 4 weeks would improve functional ability and knee muscle strength of patients with knee osteoarthritis.
- The outcome of standing balance training is different from isometric knee extension exercise.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| G1 | Experimental | Behavioral: Standing balance exerciseStanding balance and mini squat training |
| G2 | Active comparator | Behavioral: Isometric knee extension exerciseIsometric knee extension exercise |
Who may qualify
- Ages
- 50 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Clinical criteria for knee osteoarthritis
Key exclusion criteria (5 listed)
- cardiovascular disease
- Parkinsonism
- osteoporosis
- inability to walk for 15 meters
- intra-articular injections
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Standing balance exerciseStanding balance and mini squat exercise performed 30 times/day/side, 5 days/week, for 4 weeks. | Behavioural | G1 |
| Isometric knee extension exerciseIsometric knee extension exercise performed 10 repetitions/set, 3 sets/day, 5 days/week for 4 weeks | Behavioural | G2 |
Primary outcome
Knee osteoarthritis outcome scores (KOOS)
Time frame: 4 weeks
2 secondary outcomes
Knee muscle peak torque
Time frame: 4 weeks
Aggregate functional performance time
Time frame: 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jun 2008.
- Derived from this study: PubMed 19226239Chaipinyo K, Karoonsupcharoen O. No difference between home-based strength training and home-based balance training on pain in patients with knee osteoarthritis: a randomised trial. Aust J Physiother. 2009;55(1):25-30. doi: 10.1016/s0004-9514(09)70057-1.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kanda Chaipinyo, PT,PhD. principal investigator
Srinakharinwirot University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Standing balance exercise and Isometric knee extension exercise in people with Osteoarthritis, Knee, run by Srinakharinwirot University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Jun 2008. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee osteoarthritis outcome scores (KOOS) (time frame: 4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00687726, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jun 2008.