Acute Renal FailureStV 11-2008NCT00743132
Novel Prediction Score for Postoperative Acute Renal Failure (ARF) Following Liver Resection
An observational study of Acute Renal Failure, run by University of Zurich at 1 site in Switzerland.
Trial summary
ARF is a frequent event after hepatic resection and therefore clinically highly relevant. There is limited evidence on the incidence of postoperative ARF and its clinical relevance in patients undergoing liver resection. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Acute Renal Failure
- How many people
- 569 participants
- Where
- 1 siteSwitzerland
- Study dates
- Apr 2008to Dec 2008
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with benign and malign liver diseases of the Swiss HPB (Hepato-Pancreato-Biliary) Center undergoing liver resection from 2002 - 2007
Who may be able to join
- Patient age >/= 18 years
- Benign and malign liver diseases
Who cannot join
- Trauma cases
Trial locations and contacts
1 site in 1 country.
Switzerland1 site
Swiss HPB (Hepato-Pancreato-Biliary) Center of the University Hospital Zurich
Zurich, Canton of Zurich, 8091
About this study
ARF is a frequent event after hepatic resection and therefore clinically highly relevant.
There is limited evidence on the incidence of postoperative ARF and its clinical relevance in patients undergoing liver resection.
This study will evaluate the incidence of acute renal failure (ARF) after liver resection and its impact on postoperative mortality.
Read the detailed description
ARF is a frequent event after hepatic resection and therefore clinically highly relevant.
There is limited evidence on the incidence of postoperative ARF and its clinical relevance in patients undergoing liver resection.
This study will evaluate the incidence of acute renal failure (ARF) after liver resection and its impact on postoperative mortality.
- Conditions
- Acute Renal Failure
- Keywords
- evaluation, incidence, liver surgery, resection, impact, postoperative, mortality
- Medical subject headings
- Acute Kidney Injury, Tooth, Impacted
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| 1 | Postoperative no renal dysfunction | |
| 2 | Postoperative renal dysfunction |
What is being measured
The primary outcome is the main question the study is designed to answer.
Predictor score
Incidence of ARF Length of hospital stay
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Aug 2008 (estimated)
- Study startApr 2008
- Primary completionOct 2008
- Study completionDec 2008
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Acute Renal FailureStudies of the same condition, open and under way.
- More trials run by University of ZurichThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 569 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Zurich
- Sponsor type
- University, hospital or other
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00743132
- Sponsor's protocol ID
- StV 11-2008
- Other IDs
- StV 11-2008
- Acronym
- StV 11-2008
- Status last verified
- Jan 2010
- First submitted
- 27 Aug 2008
- Last updated
- 25 Jan 2010
- Results posted
- No
- Data monitoring committee
- No
Publications
Slankamenac K, Breitenstein S, Held U, Beck-Schimmer B, Puhan MA, Clavien PA. Development and validation of a prediction score for postoperative acute renal failure following liver resection. Ann Surg. 2009 Nov;250(5):720-8. doi: 10.1097/SLA.0b013e3181bdd840.
PubMed 19809295
Study at a glance
From the registry record, last updated by the sponsor on 25 Jan 2010. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Novel Prediction Score for Postoperative Acute Renal Failure (ARF) Following Liver Resection
- ClinicalTrials.gov ID
- NCT00743132
- Acronym / sponsor ID
- StV 11-2008 / StV 11-2008
- Conditions
- Acute Renal Failure
- Keywords
- evaluation, incidence, liver surgery, resection, impact, postoperative, mortality
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 569 participants (actual)
- Lead sponsor
- University of ZurichUniversity, hospital or other
- Study start
- Apr 2008
- Primary completion
- Oct 2008 (actual)
- Study completion
- Dec 2008 (actual)
- First posted
- 28 Aug 2008 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
ARF is a frequent event after hepatic resection and therefore clinically highly relevant.
There is limited evidence on the incidence of postoperative ARF and its clinical relevance in patients undergoing liver resection.
This study will evaluate the incidence of acute renal failure (ARF) after liver resection and its impact on postoperative mortality.
Detailed description
ARF is a frequent event after hepatic resection and therefore clinically highly relevant.
There is limited evidence on the incidence of postoperative ARF and its clinical relevance in patients undergoing liver resection.
This study will evaluate the incidence of acute renal failure (ARF) after liver resection and its impact on postoperative mortality.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| 1 | – | –Postoperative no renal dysfunction |
| 2 | – | –Postoperative renal dysfunction |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with benign and malign liver diseases of the Swiss HPB (Hepato-Pancreato-Biliary) Center undergoing liver resection from 2002 - 2007
Key inclusion criteria (2 listed)
- Patient age >/= 18 years
- Benign and malign liver diseases
Key exclusion criteria (1 listed)
- Trauma cases
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Predictor score
Incidence of ARF Length of hospital stay
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jan 2010.
- Derived from this study: PubMed 19809295Slankamenac K, Breitenstein S, Held U, Beck-Schimmer B, Puhan MA, Clavien PA. Development and validation of a prediction score for postoperative acute renal failure following liver resection. Ann Surg. 2009 Nov;250(5):720-8. doi: 10.1097/SLA.0b013e3181bdd840.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Acute Renal Failure, run by University of Zurich at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jan 2010. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Predictor score. The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00743132, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jan 2010; AzTrials last refreshed its copy on 7 Nov 2026.