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Total Knee ArthroplastyNCT00797875

PNF Stretching for TKA on ROM

A study testing PNF stretching and passive stretching in people with Total Knee Arthroplasty, run by National Taiwan University Hospital at 1 site in Taiwan.

Unknown status

Status not confirmed. The sponsor has not verified this record for over two years, so it may be out of date.

Official record
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Trial summary

To investigate immediate and short term effects on angle of knee flexion, intensity of pain, strength of the knee extensor, and function of the lower extremity by using PNF stretching technique in patients with total knee arthroplasty. hypothesis:TKA patients may increase ROM after PNF stretching Read more about this study

Who is it for?
Any age
Conditions the study is for
Total Knee Arthroplasty
What is being tested?
PNF stretching and passive stretching
Type of treatment
Surgery or procedure
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
1 siteTaiwan
Study dates
Dec 2008to Dec 2008
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages Any age
  • All sexes
  • No healthy volunteers
  • Child, Adult, Older adult

Who may be able to join

  • OA knee
  • primary unilateral TKA

Who cannot join

  • knee flexion>110 or thigh girth > 55 cm
  • poor cognition
  • CNS or PNS neuromuscular disease
  • received operation in recent 3 months
  • joint infection and loosening
  • revision total knee arthroplasty
  • complication during follow up

Trial locations and contacts

1 site in 1 country.

Taiwan1 site
  • National Taiwan University Hospital

    Taipei, 100

    Huei-Ming Chai, PHD, 02-33228140, hmchai@ntu.edu.tw

Other trials in Taiwan

About this study

Official title: The Effects of PNF Stretching on Knee Motion Following TKA

To investigate immediate and short term effects on angle of knee flexion, intensity of pain, strength of the knee extensor, and function of the lower extremity by using PNF stretching technique in patients with total knee arthroplasty.

hypothesis:TKA patients may increase ROM after PNF stretching

Read the detailed description

Proprioceptive neuromuscular facilitation(PNF) is defined as a treatment method that promotes or hastens the response of the neuromuscular mechanism through stimulation of proprioceptors within the related muscles or joints. PNF stretching technique is a therapeutic technique using the PNF concept to the related muslces either to increase neuro-inhibition mechanism for releasing muscle spasm and elongating muscle length, or to increase neuro-excitation mechanism for enhancing muscle strength. Improvement in range of motion using PNF stretching technique has been reported superior to other techniques in previous literature, but those studies have only been done in healthy adults. Less is known in the effect of PNF stretching on improvement in joint restriction. Range of motion limitation usually disturbed the patients with total knee arthroplasty. PNF stretching techniques has been used frequently for patients with total knee arthroplasty in clinical practice to increase range of motion effectively and reduced knee pain during exercise. However there is no evidence-based research in such a technique for patients with total knee arthroplasty. This research project, therefore, will explore application of PNF stretch in changes of knee flexion, pain, muscle strength, and function of the lower extremity following total knee arthroplasty.

Purposes: To investigate immediate and short term effects on angle of knee flexion, intensity of pain, strength of the knee extensor, and function of the lower extremity by using PNF stretching technique in patients with total knee arthroplasty.

Method: Sixty patients who received total knee arthroplasty in National Taiwan University Hospital will be recruited in this study. They will be allocated randomly into either experimental or control groups. Conventional physical therapy will be given to all participants. Besides, the experimental group will assume PNF stretching technique from the third post-operative day to the day of discharge. This technique will be executed by the same physical therapist, including 5 trials of isometric knee extension for 6 s, followed by active knee flexion to the maximum range immediately, and holding for 10s. The rest interval will be 10 s. For the control group, passive stretch technique with the same treatment time will be given, instead. All participants will be asked to do home exercises after discharged from the hospital. The outcome measures will be given before and after the first session treatment on the same day, on the day of discharge, and one month after the operation. The variables measured will be (1) knee flexion angle measured with a universal goniometer, (2) maximum voluntary isometric strength of the knee extensor measured with a hand-held dynamometer, (3) pain score using pain visual analog scale, (4) function performance of the lower extremity measured with timed up and go test, (5) Knee Injury and Osteoarthritis Outcome Score (KOOS) to record 5 dimensions including the symptoms, stiffness, pain, difficulties in knee functions and/or daily activities, limitations in sports or recreational participation, and quality of life.

Being tested
PNF stretching, passive stretching
Keywords
proprioceptive neuromuscular facilitation stretching technique, total knee arthroplasty, range of motion

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • PNF stretchingProcedure or surgery

    PNF stretching x 5 repetitions and continue 3 days

  • passive stretchingProcedure or surgery

    passive stretching x 5 repetitions continue 3 days

Study groups in NCT00797875
Study groupRoleWhat they receive
1ExperimentalPNF stretching x 5 repetitions for 3 days
Receives: Procedure: PNF stretching
2Active comparatorpassive stretching
Receives: Procedure: passive stretching

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. knee flexion angle

    Measured: baseline and follow up

Secondary outcomes (4)
  1. VAS pain score

    Measured: baseline and follow up

  2. knee extensor strength

    Measured: baseline and follow up

  3. time up and go test time

    Measured: baseline and follow up

  4. KOOS score

    Measured: baseline and follow up

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted25 Nov 2008 (estimated)
  2. Study startDec 2008
  3. Primary completionDec 2008 (estimated)
  4. Study completionDec 2008 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Double blind
Who is masked
Participant, Outcomes assessor
Enrolment
60 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT00797875
Sponsor's protocol ID
200803064R
Status last verified
Nov 2008
First submitted
24 Nov 2008
Last updated
25 Nov 2008
Results posted
No
Data monitoring committee
No

Questions about this trial

What is this clinical trial studying?

A study testing PNF stretching and passive stretching in people with Total Knee Arthroplasty, run by National Taiwan University Hospital at 1 site in Taiwan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: status not confirmed, as of the sponsor's last update on 25 Nov 2008. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Results are not available in the source record.

How can a doctor refer a patient or contact the research team?

Contact Shiun-Jeng Lin (0939803219, seanjeng2000@yahoo.com.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

knee flexion angle (time frame: baseline and follow up). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Nov 2008; AzTrials last refreshed its copy on 31 Oct 2026.

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