General ParesisNCT00921648
Clinical Findings in General Paresis
An observational study of General Paresis, run by Xijing Hospital at 1 site in China.
Trial summary
This is a study of the clinical and neuroimaging of general paresis. The investigators studied six patients with general paresis. Read more about this study
- Who is it for?
- Ages 30 to 60 years
- Conditions the study is for
- General Paresis
- How many people
- 6 participants
- Where
- 1 siteChina
- Study dates
- Apr 2008to Jan 2009
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 60 years
- All sexes
- No healthy volunteers
- Adult
Study population: 6 cases
Who may be able to join
- EEG MR
Who cannot join
- Serological test
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Xijing HOSPITAL, Fourth Military Medical University, China
This is a study of the clinical and neuroimaging of general paresis. The investigators studied six patients with general paresis.
Read the detailed description
Inclusion Criteria:
- Mental disorders
- positive TPHA in CSF and sera
- HIV-negative serology by ELISA
Exclusion Criteria:
- Negative TPHA in CSF and sera
- No image data
- Conditions
- General Paresis
- Keywords
- EEG, general paresis, MRI, neurosyphilis
- Medical subject headings
- Neurosyphilis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Mr Q, 40 years old | Dementia, sensory aphasia, irritability, hallucination MRI showed cortical lesion, mesial temporal lobe atrophy. | |
| Mr Guo,35 years old | Dementia, sensory aphasia, tremor, gait disturbance MRI showed cortical lesion, enlarged ventricle, white matter lesion, cerebral atrophy | |
| Mr Zhang,40 years old | Dementia, apraxia of speech, gatism , irritability, insomnia, gait disturbance MRI showed white matter lesion, cerebral atrophy. | |
| Mr Liu,40 years old | Dementia, apraxia of speech, irritability, insomnia MRI showed normal. | |
| Mr Zhang,54 years old | Dementia, apraxia of speech MRI showed white matter lesion, cerebral atrophy. |
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jun 2009 (estimated)
- Study startApr 2008
- Primary completionDec 2008
- Study completionJan 2009
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for General ParesisStudies of the same condition, open and under way.
- More trials run by Xijing HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- Xijing Hospital
- Sponsor type
- University, hospital or other
- Investigators
- yuangui huang, MD, Study director, department of neurology ,xijing hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00921648
- Sponsor's protocol ID
- 20080301
- Status last verified
- Jun 2009
- First submitted
- 21 Oct 2008
- Last updated
- 16 Jun 2009
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 16 Jun 2009. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Xijing HOSPITAL, Fourth Military Medical University, China
- ClinicalTrials.gov ID
- NCT00921648
- Acronym / sponsor ID
- 20080301
- Conditions
- General Paresis
- Keywords
- EEG, general paresis, MRI, neurosyphilis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 6 participants (actual)
- Lead sponsor
- Xijing HospitalUniversity, hospital or other
- Study start
- Apr 2008
- Primary completion
- Dec 2008 (actual)
- Study completion
- Jan 2009 (actual)
- First posted
- 16 Jun 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a study of the clinical and neuroimaging of general paresis. The investigators studied six patients with general paresis.
Detailed description
Inclusion Criteria:
- Mental disorders
- positive TPHA in CSF and sera
- HIV-negative serology by ELISA
Exclusion Criteria:
- Negative TPHA in CSF and sera
- No image data
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| Mr Q, 40 years old | – | –Dementia, sensory aphasia, irritability, hallucination MRI showed cortical lesion, mesial temporal lobe atrophy. |
| Mr Guo,35 years old | – | –Dementia, sensory aphasia, tremor, gait disturbance MRI showed cortical lesion, enlarged ventricle, white matter lesion, cerebral atrophy |
| Mr Zhang,40 years old | – | –Dementia, apraxia of speech, gatism , irritability, insomnia, gait disturbance MRI showed white matter lesion, cerebral atrophy. |
| Mr Liu,40 years old | – | –Dementia, apraxia of speech, irritability, insomnia MRI showed normal. |
| Mr Zhang,54 years old | – | –Dementia, apraxia of speech MRI showed white matter lesion, cerebral atrophy. |
Who may qualify
- Ages
- 30 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- 6 cases
Key inclusion criteria (1 listed)
- EEG MR
Key exclusion criteria (1 listed)
- Serological test
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jun 2009.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
yuangui huang, MD study director
department of neurology ,xijing hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of General Paresis, run by Xijing Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jun 2009. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jun 2009.