Arrhythmias, CardiacNCT00921986
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
An observational study of Arrhythmias, Cardiac, run by The Cleveland Clinic at 1 site in United States.
Trial summary
Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Arrhythmias, Cardiac
- How many people
- 2,000 participants
- Where
- 1 siteUnited States
- Study dates
- Mar 2009to Dec 2035
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Patients undergoing arrhythmia procedures, cardiac surgery or inpatient or outpatient evaluations for arrhythmias at the Cleveland Clinic or from outside collaborative institutions or from other clinical trials.
Who may be able to join
- Male or female at least 18 years old
- Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.
Who cannot join
- Subjects previously enrolled in the Arrhythmia BioBank
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
Mina K. Chung, MD
David R. Van Wagoner, Ph.D.
About this study
Official title: Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank)
Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes.
Read the detailed description
The long-term objective of this research is to find genes and biologic pathways causing arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the investigators will collect comprehensive phenotypic data and corresponding blood and/or tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia evaluation and/or treatment, and control subjects without arrhythmias. This biorepository will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for de-identified samples and data from outside institutions and clinical trials.
- Conditions
- Arrhythmias, Cardiac
- Keywords
- genetics, biorepository, cardiac death, atrial fibrillation, ventricular fibrillation, ventricular tachycardia, supraventricular tachycardias, premature ventricular complexes, premature atrial complexes, atrioventricular and intraventricular blocks, sinus node dysfunction, syncope, vasovagal reactivity, postural orthostatic tachycardia syndrome
- Medical subject headings
- Arrhythmias, Cardiac, Death, Atrial Fibrillation, Ventricular Fibrillation, Tachycardia, Ventricular, Tachycardia, Supraventricular, Ventricular Premature Complexes, Atrial Premature Complexes
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Arrhythmias | Patients with arrhythmias | |
| Control Subjects | Subjects that do not have a history of cardiac arrhythmias. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Genetic variants associated with arrhythmias
Genome-wide association study of arrhythmias
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2009 (estimated)
- Study startMar 2009
- Primary completionDec 2035 (estimated)
- Study completionDec 2035 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Arrhythmias, CardiacStudies of the same condition, open and under way.
- More trials run by The Cleveland ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 2,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- The Cleveland Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mina Chung, MD, The Cleveland Clinic
- Investigators
- Mina K. Chung, MD, Principal investigator, The Cleveland Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00921986
- Sponsor's protocol ID
- 09-176
- Status last verified
- Sep 2026
- First submitted
- 15 Jun 2009
- Last updated
- 14 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank)
- ClinicalTrials.gov ID
- NCT00921986
- Acronym / sponsor ID
- 09-176
- Conditions
- Arrhythmias, Cardiac
- Keywords
- genetics, biorepository, cardiac death, atrial fibrillation, ventricular fibrillation, ventricular tachycardia, supraventricular tachycardias, premature ventricular complexes
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 2,000 participants (estimated)
- Lead sponsor
- The Cleveland ClinicUniversity, hospital or other
- Study start
- Mar 2009 (actual)
- Primary completion
- Dec 2035 (estimated)
- Study completion
- Dec 2035 (estimated)
- First posted
- 17 Jun 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes.
Detailed description
The long-term objective of this research is to find genes and biologic pathways causing arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the investigators will collect comprehensive phenotypic data and corresponding blood and/or tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia evaluation and/or treatment, and control subjects without arrhythmias. This biorepository will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for de-identified samples and data from outside institutions and clinical trials.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Arrhythmias | – | –Patients with arrhythmias |
| Control Subjects | – | –Subjects that do not have a history of cardiac arrhythmias. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Patients undergoing arrhythmia procedures, cardiac surgery or inpatient or outpatient evaluations for arrhythmias at the Cleveland Clinic or from outside collaborative institutions or from other clinical trials.
Key inclusion criteria (2 listed)
- Male or female at least 18 years old
- Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.
Key exclusion criteria (1 listed)
- Subjects previously enrolled in the Arrhythmia BioBank
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Genetic variants associated with arrhythmias
Time frame: Baseline
Genome-wide association study of arrhythmias
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mina K. Chung, MD principal investigator
The Cleveland Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Arrhythmias, Cardiac, run by The Cleveland Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 14 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mina K. Chung, MD (216.444.2290, chungm@ccf.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Genetic variants associated with arrhythmias (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Sep 2026.