Obesity PreventionNCT00980941
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
A study testing soup with or without starch in people with Obesity Prevention and Diabetes Prevention, run by University of Toronto at 1 site in Canada.
Trial summary
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular corn or maltodextrin starches or no added starch at one week intervals. Read more about this study
- Who is it for?
- Ages 20 to 30 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Obesity Prevention, Diabetes Prevention
- What is being tested?
- soup with or without starch
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 17 participants
- Where
- 1 siteCanada
- Study dates
- Dec 2007to Jun 2009
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 30 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy males with a BMI of 20-24.9 kg/m2
Who cannot join
- Females
- Smokers
- Breakfast skippers
- Individuals with diabetes or other metabolic diseases
Trial locations and contacts
1 site in 1 country.
Canada1 site
Department of Nutritional Studies, University of Toronto
Toronto, Ontario, M5S 3E2
About this study
Official title: The Effect of Different Types of Starch on Glycemic Response, Subjective Appetite and Short-term Food Intake in Young Men
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular corn or maltodextrin starches or no added starch at one week intervals. The investigators measured food intake at 30 minutes, appetite and blood sugar.
- Conditions
- Obesity Prevention, Diabetes Prevention
- Being tested
- soup with or without starch
- Keywords
- starch, carbohydrates, blood glucose, food intake, satiety, appetite
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
soup with or without starchDietary supplement
| Study group | Role | What they receive |
|---|---|---|
| Soup with no added starch | Experimental | Not described Receives: Dietary Supplement: soup with or without starch |
| Soup + 50 g of whole grain starch | Experimental | Not described Receives: Dietary Supplement: soup with or without starch |
| Soup + 50 g of high amylose corn starch | Experimental | Not described Receives: Dietary Supplement: soup with or without starch |
| Soup + 50 g of regular corn starch | Experimental | Not described Receives: Dietary Supplement: soup with or without starch |
| Soup + 50 g maltodextrin starch | Experimental | Not described Receives: Dietary Supplement: soup with or without starch |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood glucose
Measured: 0-170 min
Food intake
Measured: at 30 min after the treatment
Appetite
Measured: 0-170 min
Secondary outcomes (2)
Water intake
Measured: at 30 min
Palatability of treatments
Measured: 0-170 min
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Sep 2009 (estimated)
- Study startDec 2007
- Primary completionApr 2008
- Study completionJun 2009
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Obesity PreventionStudies of the same condition, open and under way.
- More trials run by University of TorontoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 17 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Toronto
- Sponsor type
- University, hospital or other
- Collaborators
- Ingredion Incorporated
- Investigators
- Harvey Anderson, Ph.D., Principal investigator, University of Toronto
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00980941
- Sponsor's protocol ID
- Starch study 1
- Other IDs
- National Starch_ethics_21513
- Status last verified
- Sep 2009
- First submitted
- 18 Sep 2009
- Last updated
- 21 Sep 2009
- Results posted
- No
- Data monitoring committee
- Yes
Publications
Anderson GH, Cho CE, Akhavan T, Mollard RC, Luhovyy BL, Finocchiaro ET. Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men. Am J Clin Nutr. 2010 Apr;91(4):932-9. doi: 10.3945/ajcn.2009.28443. Epub 2010 Feb 17.
PubMed 20164321
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2009. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Different Types of Starch on Glycemic Response, Subjective Appetite and Short-term Food Intake in Young Men
- ClinicalTrials.gov ID
- NCT00980941
- Acronym / sponsor ID
- Starch study 1
- Conditions
- Obesity Prevention, Diabetes Prevention
- Keywords
- starch, carbohydrates, blood glucose, food intake, satiety, appetite
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 17 participants (actual)
- Lead sponsor
- University of TorontoUniversity, hospital or other
- Collaborators
- Ingredion Incorporated
- Study start
- Dec 2007
- Primary completion
- Apr 2008 (actual)
- Study completion
- Jun 2009 (actual)
- First posted
- 21 Sep 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular corn or maltodextrin starches or no added starch at one week intervals. The investigators measured food intake at 30 minutes, appetite and blood sugar.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (participant)
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| Soup with no added starch | Experimental | Dietary Supplement: soup with or without starch |
| Soup + 50 g of whole grain starch | Experimental | Dietary Supplement: soup with or without starch |
| Soup + 50 g of high amylose corn starch | Experimental | Dietary Supplement: soup with or without starch |
| Soup + 50 g of regular corn starch | Experimental | Dietary Supplement: soup with or without starch |
| Soup + 50 g maltodextrin starch | Experimental | Dietary Supplement: soup with or without starch |
Who may qualify
- Ages
- 20 to 30 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Healthy males with a BMI of 20-24.9 kg/m2
Key exclusion criteria (4 listed)
- Females
- Smokers
- Breakfast skippers
- Individuals with diabetes or other metabolic diseases
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| soup with or without starch | Dietary supplement | Soup + 50 g maltodextrin starch, Soup + 50 g of high amylose corn starch, Soup + 50 g of regular corn starch, Soup + 50 g of whole grain starch, Soup with no added starch |
Primary outcome
Blood glucose
Time frame: 0-170 min
Food intake
Time frame: at 30 min after the treatment
Appetite
Time frame: 0-170 min
2 secondary outcomes
Water intake
Time frame: at 30 min
Palatability of treatments
Time frame: 0-170 min
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2009.
- Derived from this study: PubMed 20164321Anderson GH, Cho CE, Akhavan T, Mollard RC, Luhovyy BL, Finocchiaro ET. Relation between estimates of cornstarch digestibility by the Englyst in vitro method and glycemic response, subjective appetite, and short-term food intake in young men. Am J Clin Nutr. 2010 Apr;91(4):932-9. doi: 10.3945/ajcn.2009.28443. Epub 2010 Feb 17.
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Healthy Volunteers
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Harvey Anderson, Ph.D. principal investigator
University of Toronto
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing soup with or without starch in people with Obesity Prevention and Diabetes Prevention, run by University of Toronto at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Sep 2009. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Blood glucose (time frame: 0-170 min). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00980941, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2009.