Heart DiseaseNCT01027507
Postprandial Hemodynamics
An observational study of Heart Disease, run by Skane University Hospital at 1 site in Sweden.
Trial summary
To study the postprandial alterations in hemodynamics and blood pressure in relation to gastric emptying rate, postprandial blood glucose, plasma concentrations of insulin, satiety in healthy subjects. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Heart Disease
- How many people
- 23 participants
- Where
- 1 siteSweden
- Study dates
- Jan 2009to Nov 2009
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Healthy subjects without symptoms or a history of gastrointestinal disease, abdominal surgery or diabetes mellitus, were included in this crossover study.
Who may be able to join
- Healthy subjects
Who cannot join
- history of gastrointestinal disease, abdominal surgery or diabetes mellitus
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Relationship Between Postprandial Alterations in Hemodynamics, Blood Pressure, Blood Glucose, Insulin Concentrations, Gastric Emptying, and Satiety
To study the postprandial alterations in hemodynamics and blood pressure in relation to gastric emptying rate, postprandial blood glucose, plasma concentrations of insulin, satiety in healthy subjects.
Read the detailed description
Ingestion of a meal increase blood flow to the gastrointestinal organs and affects the heart rate, blood pressure, and cardiac output. It is not known through wich mechanisms the heart function changes affects after a meal.
- Conditions
- Heart Disease
- Medical subject headings
- Heart Diseases
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Dec 2009 (estimated)
- Study startJan 2009
- Study completionNov 2009
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Heart DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Enrolment
- 23 participants (actual)
Sponsor and investigators
- Lead sponsor
- Skane University Hospital
- Sponsor type
- University, hospital or other
- Investigators
- Joanna Hlebowicz, MD, PhD, Principal investigator, Skane University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01027507
- Sponsor's protocol ID
- 353/2008b
- Status last verified
- Dec 2009
- First submitted
- 7 Dec 2009
- Last updated
- 8 Dec 2009
- Results posted
- No
- Data monitoring committee
- Yes
Publications
Dencker M, Bjorgell O, Hlebowicz J. Effect of a standardized meal on inflammatory biomarkers. Scand J Clin Lab Invest. 2026;86(2):95-109. doi: 10.1080/00365513.2026.2630318. Epub 2026 Feb 14.
PubMed 41689559Dencker M, Bjorgell O, Hlebowicz J. Effect of food intake on 92 oncological biomarkers by the Proseek Oncology II panel. BMC Res Notes. 2019 Apr 2;12(1):199. doi: 10.1186/s13104-019-4237-9.
PubMed 30940215Hlebowicz J, Lindstedt S, Bjorgell O, Dencker M. The effect of endogenously released glucose, insulin, glucagon-like peptide 1, ghrelin on cardiac output, heart rate, stroke volume, and blood pressure. Cardiovasc Ultrasound. 2011 Dec 29;9:43. doi: 10.1186/1476-7120-9-43.
PubMed 22206473Hlebowicz J, Lindstedt S, Bjorgell O, Dencker M. Relationship between postprandial changes in cardiac left ventricular function, glucose and insulin concentrations, gastric emptying, and satiety in healthy subjects. Nutr J. 2011 Mar 23;10:26. doi: 10.1186/1475-2891-10-26.
PubMed 21429209
Study at a glance
From the registry record, last updated by the sponsor on 8 Dec 2009. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship Between Postprandial Alterations in Hemodynamics, Blood Pressure, Blood Glucose, Insulin Concentrations, Gastric Emptying, and Satiety
- ClinicalTrials.gov ID
- NCT01027507
- Acronym / sponsor ID
- 353/2008b
- Conditions
- Heart Disease
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 23 participants (actual)
- Lead sponsor
- Skane University HospitalUniversity, hospital or other
- Study start
- Jan 2009
- Study completion
- Nov 2009 (actual)
- First posted
- 8 Dec 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To study the postprandial alterations in hemodynamics and blood pressure in relation to gastric emptying rate, postprandial blood glucose, plasma concentrations of insulin, satiety in healthy subjects.
Detailed description
Ingestion of a meal increase blood flow to the gastrointestinal organs and affects the heart rate, blood pressure, and cardiac output. It is not known through wich mechanisms the heart function changes affects after a meal.
Study design
- Observational model
- Case only
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Healthy subjects without symptoms or a history of gastrointestinal disease, abdominal surgery or diabetes mellitus, were included in this crossover study.
Key inclusion criteria (1 listed)
- Healthy subjects
Key exclusion criteria (1 listed)
- history of gastrointestinal disease, abdominal surgery or diabetes mellitus
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Dec 2009.
- Derived from this study: PubMed 41689559Dencker M, Bjorgell O, Hlebowicz J. Effect of a standardized meal on inflammatory biomarkers. Scand J Clin Lab Invest. 2026;86(2):95-109. doi: 10.1080/00365513.2026.2630318. Epub 2026 Feb 14.
- Derived from this study: PubMed 30940215Dencker M, Bjorgell O, Hlebowicz J. Effect of food intake on 92 oncological biomarkers by the Proseek Oncology II panel. BMC Res Notes. 2019 Apr 2;12(1):199. doi: 10.1186/s13104-019-4237-9.
- Derived from this study: PubMed 22206473Hlebowicz J, Lindstedt S, Bjorgell O, Dencker M. The effect of endogenously released glucose, insulin, glucagon-like peptide 1, ghrelin on cardiac output, heart rate, stroke volume, and blood pressure. Cardiovasc Ultrasound. 2011 Dec 29;9:43. doi: 10.1186/1476-7120-9-43.
- Derived from this study: PubMed 21429209Hlebowicz J, Lindstedt S, Bjorgell O, Dencker M. Relationship between postprandial changes in cardiac left ventricular function, glucose and insulin concentrations, gastric emptying, and satiety in healthy subjects. Nutr J. 2011 Mar 23;10:26. doi: 10.1186/1475-2891-10-26.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Joanna Hlebowicz, MD, PhD principal investigator
Skane University Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Heart Disease, run by Skane University Hospital at 1 site in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Dec 2009. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01027507, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Dec 2009.