Central Venous PressureNCT01099254
Internal Jugular Vein Cross Sectional Area
An observational study of Central Venous Pressure, run by University of Iowa at 1 site in United States.
Trial summary
The Trendelenburg position is used to distend the central veins, improving both success and safety of vascular cannulation. The purpose of this study is to measure the cross-sectional area of the internal jugular vein (IJV) in three different positions, using surface ultrasound. Read more about this study
- Who is it for?
- Ages 18 to 120 years
- Conditions the study is for
- Central Venous Pressure
- How many people
- 38 participants
- Where
- 1 siteUnited States
- Study dates
- Aug 2007to Mar 2010
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 120 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients admitted to Intensive care unit.
Who may be able to join
- adult medical or surgical ICU patients who have preexisting central venous (jugular/subclavian only) catheters.
Who cannot join
- subjects with only a femoral venous catheter.
- subjects whose CVP measurement by the indwelling catheter exceeds 20cm of water.
- subjects younger than 18 years old.
- inability to obtain informed consent from the subject or the subjects authorized representative.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Position on Cross Sectional Area of IJV
The Trendelenburg position is used to distend the central veins, improving both success and safety of vascular cannulation. The purpose of this study is to measure the cross-sectional area of the internal jugular vein (IJV) in three different positions, using surface ultrasound.
- Conditions
- Central Venous Pressure
- Keywords
- CVP, US, Trendelenburg position, Ultrasound, Head Down Tilt
What is being measured
The primary outcome is the main question the study is designed to answer.
Effect of trendelenburg and reverse trendelenburg position on the cross sectional area of the internal jugular vein
There will be substantial anatomic variation in venous size. Further, Trendelenburg positioning will have little impact on venous cross-sectional area in most subjects when compared with supine.
Measured: At time of data collection: physiologic study
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2010 (estimated)
- Study startAug 2007
- Primary completionMar 2010
- Study completionMar 2010
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Central Venous PressureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 38 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Iowa
- Sponsor type
- University, hospital or other
- Investigators
- Gregory A Schmidt, mD, Principal investigator, Roy J. & Lucille A. Carver College of Medicine, University of Iowa
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01099254
- Sponsor's protocol ID
- 20076778
- Status last verified
- Nov 2023
- First submitted
- 29 Mar 2010
- Last updated
- 15 Nov 2023
- Results posted
- No
- Data monitoring committee
- No
Publications
Bazaral M, Harlan S. Ultrasonographic anatomy of the internal jugular vein relevant to percutaneous cannulation. Crit Care Med. 1981 Apr;9(4):307-10. doi: 10.1097/00003246-198104000-00004.
PubMed 7214938Vinayak AG, Levitt J, Gehlbach B, Pohlman AS, Hall JB, Kress JP. Usefulness of the external jugular vein examination in detecting abnormal central venous pressure in critically ill patients. Arch Intern Med. 2006 Oct 23;166(19):2132-7. doi: 10.1001/archinte.166.19.2132.
PubMed 17060544Nassar B, Deol GRS, Ashby A, Collett N, Schmidt GA. Trendelenburg position does not increase cross-sectional area of the internal jugular vein predictably. Chest. 2013 Jul;144(1):177-182. doi: 10.1378/chest.11-2462.
PubMed 23392444
Study at a glance
From the registry record, last updated by the sponsor on 15 Nov 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Position on Cross Sectional Area of IJV
- ClinicalTrials.gov ID
- NCT01099254
- Acronym / sponsor ID
- 20076778
- Conditions
- Central Venous Pressure
- Keywords
- CVP, US, Trendelenburg position, Ultrasound, Head Down Tilt
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 38 participants (actual)
- Lead sponsor
- University of IowaUniversity, hospital or other
- Study start
- Aug 2007
- Primary completion
- Mar 2010 (actual)
- Study completion
- Mar 2010 (actual)
- First posted
- 6 Apr 2010 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Trendelenburg position is used to distend the central veins, improving both success and safety of vascular cannulation. The purpose of this study is to measure the cross-sectional area of the internal jugular vein (IJV) in three different positions, using surface ultrasound.
Study design
- Observational model
- Other
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 120 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients admitted to Intensive care unit.
Key inclusion criteria (1 listed)
- adult medical or surgical ICU patients who have preexisting central venous (jugular/subclavian only) catheters.
Key exclusion criteria (4 listed)
- subjects with only a femoral venous catheter.
- subjects whose CVP measurement by the indwelling catheter exceeds 20cm of water.
- subjects younger than 18 years old.
- inability to obtain informed consent from the subject or the subjects authorized representative.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Effect of trendelenburg and reverse trendelenburg position on the cross sectional area of the internal jugular vein
Time frame: At time of data collection: physiologic study
There will be substantial anatomic variation in venous size. Further, Trendelenburg positioning will have little impact on venous cross-sectional area in most subjects when compared with supine.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Nov 2023.
- Background: PubMed 7214938Bazaral M, Harlan S. Ultrasonographic anatomy of the internal jugular vein relevant to percutaneous cannulation. Crit Care Med. 1981 Apr;9(4):307-10. doi: 10.1097/00003246-198104000-00004.
- Background: PubMed 17060544Vinayak AG, Levitt J, Gehlbach B, Pohlman AS, Hall JB, Kress JP. Usefulness of the external jugular vein examination in detecting abnormal central venous pressure in critically ill patients. Arch Intern Med. 2006 Oct 23;166(19):2132-7. doi: 10.1001/archinte.166.19.2132.
- Derived from this study: PubMed 23392444Nassar B, Deol GRS, Ashby A, Collett N, Schmidt GA. Trendelenburg position does not increase cross-sectional area of the internal jugular vein predictably. Chest. 2013 Jul;144(1):177-182. doi: 10.1378/chest.11-2462.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Gregory A Schmidt, mD principal investigator
Roy J. & Lucille A. Carver College of Medicine, University of Iowa
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Central Venous Pressure, run by University of Iowa at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Nov 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Effect of trendelenburg and reverse trendelenburg position on the cross sectional area of the internal jugular vein (time frame: At time of data collection: physiologic study). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01099254, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Nov 2023; AzTrials last refreshed its copy on 28 Oct 2026.