ER Stress,NCT01211015
Endoplasmic Reticulum Stress in Chronic Respiratory Diseases
An observational study of ER Stress, and Chronic Airway Disorders,, run by Chonbuk National University at 1 site in South Korea.
Trial summary
Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders Measurement: 1. Unfolded protein responses (UPRs) in blood (PBMCs)of patients 1. CHOP 2. GRP 78 and so on 2. Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls 1. CHOP 2. GRP 78 and so on Read more about this study
- Who is it for?
- Ages 18 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- ER Stress,, Chronic Airway Disorders,, Lung Cancer,
- How many people
- 50 participants
- Where
- 1 siteSouth Korea
- Study dates
- Jul 2010to not given
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: 1. Control group * healthy control (volunteer) 2. Disease group * chronic pulmonary lung diseases including asthma, COPD, ILD, and lung cancer
Who may be able to join
- > 18 yrs
- Definitive diagnosis as chronic pulmonary diseases by physician
Who cannot join
- Any other chronic medical illness such as DM, HTN, and other malignancy
Trial locations and contacts
1 site in 1 country.
South Korea1 site, 1 recruiting
- Recruiting
Chonbuk National University Hospital
Jeonju, Jeollabuk-do, 561-180
Yong Chul Lee, MD, PhD, 82-63-250-1664 ext. 1664, leeyc@chonbuk.ac.kr
Yong Chul Lee, MD, PhD
About this study
Official title: Endoplasmic Reticulum (ER) Stress in Patients With Various Chronic Pulmonary Diseases
Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders
Measurement:
- Unfolded protein responses (UPRs) in blood (PBMCs)of patients
- CHOP
- GRP 78 and so on
- Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls
- CHOP
- GRP 78 and so on
- Medical subject headings
- Lung Neoplasms, Lung Diseases, Interstitial
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Control group | healthy control group | |
| Disease group | asthma, COPD, ILD, lung malignancy |
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2010 (estimated)
- Study startJul 2010
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ER Stress,Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Chonbuk National University
- Sponsor type
- University, hospital or other
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01211015
- Sponsor's protocol ID
- RCPD ER stress
- Status last verified
- Sep 2010
- First submitted
- 28 Sep 2010
- Last updated
- 29 Sep 2010
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Sep 2010. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Endoplasmic Reticulum (ER) Stress in Patients With Various Chronic Pulmonary Diseases
- ClinicalTrials.gov ID
- NCT01211015
- Acronym / sponsor ID
- RCPD ER stress
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Chonbuk National UniversityUniversity, hospital or other
- Study start
- Jul 2010
- First posted
- 29 Sep 2010 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders
Measurement:
- Unfolded protein responses (UPRs) in blood (PBMCs)of patients
- CHOP
- GRP 78 and so on
- Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls
- CHOP
- GRP 78 and so on
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control group | – | –healthy control group |
| Disease group | – | –asthma, COPD, ILD, lung malignancy |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- 1. Control group * healthy control (volunteer) 2. Disease group * chronic pulmonary lung diseases including asthma, COPD, ILD, and lung cancer
Key inclusion criteria (2 listed)
- > 18 yrs
- Definitive diagnosis as chronic pulmonary diseases by physician
Key exclusion criteria (1 listed)
- Any other chronic medical illness such as DM, HTN, and other malignancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Sep 2010.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of ER Stress, and Chronic Airway Disorders,, run by Chonbuk National University at 1 site in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 29 Sep 2010. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Yong Chul Lee, MD, phD (82-63-250-1664 ext. 1664, leeyc@chonbuk.ac.kr), or a site near the patient. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Sep 2010.