StrokeNCT01211093
Acute Effects of Whole Body Vibration in Chronic Stroke
A study testing High frequency whole body vibration and Low frequency whole body vibration in people with Stroke, run by The Hong Kong Polytechnic University at 1 site in China.
Trial summary
Whole body vibration has been found to be useful in promoting bone health, balance, and muscle performance in older adults. The overall aim of the proposed study is to determine whether whole body vibration (WBV) has immediate beneficial effect in neuromotor performance in patients with stroke. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke
- What is being tested?
- High frequency whole body vibration and Low frequency whole body vibration
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteChina
- Study dates
- Nov 2009to Jul 2013
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- a diagnosis of stroke
- stroke onset >6 months
- >18 years of age
- >able to walk for short distance independently with or without walking aid
- able to understand simple verbal commands
Who cannot join
- other neurological conditions
- peripheral vascular disease
- vestibular disorders
- significant musculoskeletal disorders (e.g. rheumatoid arthritis)
- pregnancy
Trial locations and contacts
1 site in 1 country.
China1 site, 1 recruiting
- Recruiting
The Hong Kong Polytechnic University
Hong Kong
Ricky WK Lau, MSc, 85298743644, Rickylauwk@yahoo.com.hk
Marco YC Pang, PhD
About this study
Official title: The Acute Effects of Whole Body Vibration Training With Different Frequencies on Neuromotor Performance in Individuals With Stroke
Whole body vibration has been found to be useful in promoting bone health, balance, and muscle performance in older adults. The overall aim of the proposed study is to determine whether whole body vibration (WBV) has immediate beneficial effect in neuromotor performance in patients with stroke. It is hypothesized that a single session of WBV will induce significant improvement in leg muscle strength in people with chronic stroke.
- Conditions
- Stroke
- Being tested
- High frequency whole body vibration, Low frequency whole body vibration, control
- Keywords
- vibration, muscle, cerebrovascular accident, exercise, rehabilitation
- Medical subject headings
- Stroke, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High frequency whole body vibrationProcedure or surgery
Also called Whole body vibration therapy (30Hz)
1 single session (10 minutes) of whole body vibration therapy at 30 Hz
Low frequency whole body vibrationProcedure or surgery
Also called Whole body vibration therapy (20Hz)
1 single session of whole body vibration therapy at 20 Hz
controlProcedure or surgery
1 single session of standing on the vibration platform, with no vibration signals delivered.
| Study group | Role | What they receive |
|---|---|---|
| High frequency whole body vibration | Experimental | This group will receive a single 10-minute session of WBV therapy. The frequency of the vibration signals will be set at 30Hz. Receives: Procedure: High frequency whole body vibration |
| low frequency whole body vibration | Active comparator | This group will receive a single 10-minute session of WBV. The frequency of the vibration signals will be set at 20 Hz. Receives: Procedure: Low frequency whole body vibration |
| Control | Active comparator | This group will stand on the same vibration platform for 10 minutes, but no vibration will be given. Receives: Procedure: control |
What is being measured
The primary outcome is the main question the study is designed to answer.
knee extension isokinetic strength
Measured: 2 weeks
Secondary outcomes (4)
Muscle activity (electromyography) of knee extensors
Measured: during treatment
knee extension isometric strength
Measured: 2 weeks
knee flexion isometric strength
Measured: 2 weeks
knee flexion isokinetic strength
Measured: 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2010 (estimated)
- Study startNov 2009
- Primary completionApr 2013 (estimated)
- Study completionJul 2013 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by The Hong Kong Polytechnic UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- The Hong Kong Polytechnic University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Marco Yiu-Chung Pang, The Hong Kong Polytechnic University
- Investigators
- Marco YC Pang, PhD, Principal investigator, The Hong Kong Polytechnic University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01211093
- Sponsor's protocol ID
- HSEARS20091016003-01
- Status last verified
- Nov 2012
- First submitted
- 17 Sep 2010
- Last updated
- 28 Nov 2012
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 28 Nov 2012. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Acute Effects of Whole Body Vibration Training With Different Frequencies on Neuromotor Performance in Individuals With Stroke
- ClinicalTrials.gov ID
- NCT01211093
- Acronym / sponsor ID
- HSEARS20091016003-01
- Conditions
- Stroke
- Keywords
- vibration, muscle, cerebrovascular accident, exercise, rehabilitation
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- The Hong Kong Polytechnic UniversityUniversity, hospital or other
- Study start
- Nov 2009
- Primary completion
- Apr 2013 (estimated)
- Study completion
- Jul 2013 (estimated)
- First posted
- 29 Sep 2010 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Whole body vibration has been found to be useful in promoting bone health, balance, and muscle performance in older adults. The overall aim of the proposed study is to determine whether whole body vibration (WBV) has immediate beneficial effect in neuromotor performance in patients with stroke. It is hypothesized that a single session of WBV will induce significant improvement in leg muscle strength in people with chronic stroke.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| High frequency whole body vibration | Experimental | Procedure: High frequency whole body vibrationThis group will receive a single 10-minute session of WBV therapy. The frequency of the vibration signals will be set at 30Hz. |
| low frequency whole body vibration | Active comparator | Procedure: Low frequency whole body vibrationThis group will receive a single 10-minute session of WBV. The frequency of the vibration signals will be set at 20 Hz. |
| Control | Active comparator | Procedure: controlThis group will stand on the same vibration platform for 10 minutes, but no vibration will be given. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- a diagnosis of stroke
- stroke onset >6 months
- >18 years of age
- >able to walk for short distance independently with or without walking aid
- able to understand simple verbal commands
Key exclusion criteria (5 listed)
- other neurological conditions
- peripheral vascular disease
- vestibular disorders
- significant musculoskeletal disorders (e.g. rheumatoid arthritis)
- pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High frequency whole body vibrationAlso: Whole body vibration therapy (30Hz)1 single session (10 minutes) of whole body vibration therapy at 30 Hz | Procedure or surgery | High frequency whole body vibration |
| Low frequency whole body vibrationAlso: Whole body vibration therapy (20Hz)1 single session of whole body vibration therapy at 20 Hz | Procedure or surgery | low frequency whole body vibration |
| control1 single session of standing on the vibration platform, with no vibration signals delivered. | Procedure or surgery | Control |
Primary outcome
knee extension isokinetic strength
Time frame: 2 weeks
4 secondary outcomes
Muscle activity (electromyography) of knee extensors
Time frame: during treatment
knee extension isometric strength
Time frame: 2 weeks
knee flexion isometric strength
Time frame: 2 weeks
knee flexion isokinetic strength
Time frame: 2 weeks
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Nov 2012.
Related trials for Stroke
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ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
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Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
Acute Ischemic Stroke, Basilar Artery Occlusion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Marco YC Pang, PhD principal investigator
The Hong Kong Polytechnic University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High frequency whole body vibration and Low frequency whole body vibration in people with Stroke, run by The Hong Kong Polytechnic University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 28 Nov 2012. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Ricky WK Lau, MSc (85298743644, Rickylauwk@yahoo.com.hk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
knee extension isokinetic strength (time frame: 2 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Nov 2012.