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AgingNCT01211496

The Effect of Velocity Training in Functionally Limited Elderly

A study testing High-speed power training and Slow-speed strength training in people with Aging, run by University of Missouri-Columbia.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

We are exploring a unique weight-training program for men and women 65 years or older that emphasizes high speed training. We believe that the speed at which muscles move may be more important to the performance of functional tasks than how strong the muscles are. Read more about this study

Who is it for?
Ages 65 years and olderHealthy volunteers can take part
Conditions the study is for
Aging
What is being tested?
High-speed power training and Slow-speed strength training
Could I receive a placebo?
No, everyone receives an active treatment
How many people
52 participants
Where
No sites listed yet
Study dates
Jun 2004to May 2008
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 65 years and older
  • All sexes
  • Healthy volunteers accepted
  • Older adult

Who may be able to join

  • 65 years of age
  • relatively inactive
  • male or female
  • good overall health
  • living independently (not in a nursing home or care facility)

Who cannot join

  • physically active/athletic
  • heart attack or unstable angina within 6 months of consent
  • hip fracture, knee or hip replacement within 6 months of consent
  • diagnosed neurological disease
  • pulmonary disease requiring use of oxygen
  • osteoarthritis of the knee
  • severe visual or hearing impairment

About this study

Official title: High Velocity Resistance Training in Older Men and Women

We are exploring a unique weight-training program for men and women 65 years or older that emphasizes high speed training. We believe that the speed at which muscles move may be more important to the performance of functional tasks than how strong the muscles are. We are comparing velocity training with traditional strength training to determine which method has the greatest effects on muscle strength, speed of movement, functional performance and physical disability. We believe that higher speed training will improve these measures to a greater extent than simply training for increased muscle strength.

Aging also results in loss of bone mass, which increases the risk for falls and fractures. Strength training also has been shown to maintain bone mass in the elderly, but no studies have examined high velocity resistance training and maintenance of bone mass. We believe it is important to examine this aspect of velocity training before recommendations can be made.

Read the detailed description

The study compared 12 weeks of explosive high-speed power training with traditional slow-speed strength training. Outcome measures included muscle performance: leg press (LP) and knee extension (KE) one-repetition maximum (1RM) and LP peak power (PP), velocity at peak power (PPV) and force at peak power (PPF) from 40%-90% of the 1RM. Measures of function consisted of habitual and maximal gait velocity, the short physical performance battery (SPPB), forward tandem walk, and lower limb movement time (braking speed) on an automobile driving simulator.

Participants reported to the laboratory for 2 weeks of baseline measurements. On visit 1, subjects were explained the study and completed an informed consent document. On visit 2 and 3, muscle performance and functional measures were obtained. The following week, all muscle performance and functional measures were repeated to establish reliability. At the end of baseline testing, participants were randomized to treatment. Following the 12-week RT intervention, post-training muscle performance and functional measures were obtained.

Resistance Training Protocol. Volunteers randomized into high-speed power training (HSPT) and slow-speed strength training (SSST) exercised 3 times per week for 12 weeks using computer-interfaced Keiser a420 pneumatic leg press and knee extension RT equipment (Fresno, CA). For HSPT, each training session consisted of 3 sets of 12-14 repetitions at 40%1RM. Participants performed an explosive movement at high speed during the concentric phase of each repetition, paused for one-second, and performed the eccentric portion of the contraction over 2 seconds. Volunteers randomized into SSST also exercised 3 times per week for 12 weeks with each training session consisting of 3 sets of 8-10 repetitions at 80%1RM. The participants performed each movement at a slow velocity (2 s for concentric phase of the repetition), paused for one second, and performed the eccentric portion of the contraction over 2 seconds. CON met three times a week for warm-up and stretching exercises, but performed no RT. HSPT and SSST participated in the same warm-up and stretching exercises as CON.

Measures Maximal strength and power. Leg press and seated knee extension 1RM were obtained using Keiser pneumatic RT equipment fitted with a420 electronics. The seat of both the recumbent LP and KE apparatus was positioned to place the hip and knee joints between 90 and 100 degrees of flexion. The 1RM was obtained by progressively increasing resistance until the subject was no longer able to push out one repetition successfully. The Borg Scale was used to assist in evaluating when 1RM (combined with perceived maximal effort) was reached. Peak muscle power was obtained at 40%, 50%, 60%, 70%, 80% and 90% of the 1RM approximately 30 minutes after 1RM testing (8,9). Participants were instructed to exert "as fast as possible" at each relative percentage of the 1RM. Three attempts were made at each resistance and the greatest PP output obtained at each resistance was used in the analysis. The corresponding PPV and PPF were obtained for each external resistance from 40%-90% 1RM. The 1RM was measured bi-weekly in HSPT and SSST only and relative training intensity was adjusted accordingly to ensure adequate overload during training. Post-training muscle performance measures were obtained using loads relative to the initial baseline 1RM as well as the post-training 1RM.

Conditions
Aging
Being tested
High-speed power training, Slow-speed strength training
Keywords
functional testing, resistance training, velocity training, elderly, geriatric, knee, leg, leg strength

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • High-speed power trainingBehavioural

    Also called power training, weight training

    High speed resistance training, 3 sessions per week for 12 weeks

  • Slow-speed strength trainingBehavioural

    Also called weight training

    Slow speed resistance training, 3 sessions per week for 12 weeks

Study groups in NCT01211496
Study groupRoleWhat they receive
High-speed power trainingActive comparatorVolunteers randomized into High-speed power training (HSPT) will be exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 12 to 14 repetitions at 40% of maximal strength for leg press (LP) and seated knee extension (KE) exercises.
Receives: Behavioral: High-speed power training
Slow-speed strength trainingActive comparatorVolunteers randomized into Slow-speed strength training (SSST) will be exercised 3 times per week for 12 weeks. Each training session will consist of 3 sets of 8 to 10 repetitions at 80% of maximal strength for LP and KE exercises.
Receives: Behavioral: Slow-speed strength training
placebo exercise (control group)No interventionVolunteers randomized into the control group (CON) will undergo a placebo exercise intervention consisting of lower extremity range of motion and flexibility exercises performed 2 times per week with the assistance of the research staff.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Strength and Power

    The strength and power of the lower limb muscles will be measures using Keiser pneumatic leg press and knee extension exercise machines. The Keiser machines allow for the specific measurement of the contributions of force and velocity to the development of power, which will reveal whether the high-speed training protocol impacts speed-related measures of muscle performance.

    Measured: 6 months

Secondary outcomes (1)
  1. Mobility and Function

    Walking speed tests (habitual gait speed and maximal gait speed), balance (tandem walk), stair climbing performance, chair rise time, and the timed up and go test will be used as overall measures of mobility and function.

    Measured: 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted29 Sep 2010 (estimated)
  2. Study startJun 2004
  3. Primary completionMay 2008
  4. Study completionMay 2008

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Randomised
Intervention model
Factorial
Masking
Single blind
Who is masked
Investigator
Enrolment
52 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT01211496
Sponsor's protocol ID
1042318
Other IDs
R03AG025141-01
Status last verified
Oct 2016
First submitted
2 Dec 2008
Last updated
4 Oct 2016
Results posted
No
Data monitoring committee
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing High-speed power training and Slow-speed strength training in people with Aging, run by University of Missouri-Columbia.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 4 Oct 2016. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Strength and Power (time frame: 6 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Oct 2016.

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Clinical Trial NCT01211496 | AzTrials