Use of Research EvidenceNCT01257724
Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence
A study testing SHARE (Synthesized HIV/AIDS Research Evidence) in people with Use of Research Evidence, run by Ontario HIV Treatment Network at 1 site in Canada.
Trial summary
The investigators have developed an online database called 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is designed to support the use of research evidence by those working in the HIV/AIDS sector. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Use of Research Evidence
- What is being tested?
- SHARE (Synthesized HIV/AIDS Research Evidence)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 58 participants
- Where
- 1 siteCanada
- Study dates
- Mar 2011to Jan 2013
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- We will include all community-based organizations affiliated with the Canadian AIDS Society and from relevant provincial HIV/AIDS networks in Canada.
Who cannot join
- We will exclude organizations that do not have at least one key decision-maker who is comfortable participating and corresponding in English.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence: A Protocol for a Randomized Controlled Trial
The investigators have developed an online database called 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is designed to support the use of research evidence by those working in the HIV/AIDS sector. This study will evaluate whether a "full-serve" version of SHARE increases the use of research evidence by community-based organizations as compared to a "self-serve" version. The "full-serve" version of SHARE consists of several components: 1) an online searchable database of synthesized research evidence relevant to HIV/AIDS , 2) periodic emailed updates, 3) access to user-friendly summaries and 4) peer-relevance assessments. The self-serve version consists only of a listing of relevant synthesized research evidence . The investigators will also interview participants in the study to obtain feedback about SHARE, how helpful it was in their work, why it was helpful (or not helpful), what aspects were most and least helpful and why, and recommendations for improving it.
Read the detailed description
Background To support the use of research evidence by community-based organizations the investigators have developed 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is an evidence service for those working in the HIV sector. SHARE consists of several components: 1) an online searchable database of HIV-relevant systematic reviews (retrievable based on a taxonomy of topics related to HIV/AIDS and open text search), 2) periodic email updates, 3) access to user-friendly summaries, and 4) peer relevance assessments. The objective is to evaluate whether this "full serve" evidence service increases the use of research evidence by community-based organizations as compared to a "self-serve" evidence service.
Methods/design The investigators will conduct a two-arm randomized controlled trial (RCT), along with a follow-up qualitative process study to explore the findings in greater depth. All community-based organizations affiliated with Canadian AIDS Society (n=120) will be invited to participate and will be randomized to receive either the "full-serve" version of SHARE or the "self-serve" version (a listing of relevant systematic reviews with links to records on PubMed and worksheets that help community-based organizations find and use research evidence) using a simple randomized design. All management and staff from each organization will be provided access to the version of SHARE that their organization is allocated to. The trial duration will be 10 months (two-month baseline period, six-month intervention period, and two month cross-over period), the primary outcome measure will be the mean number of logins/month/organization (averaged across the number of users from each organization) between baseline and the end of the intervention period and the secondary outcome will be intention to use research evidence as measured by a survey administered to one key decision-maker from each organization. For the qualitative study, one key organizational decision-maker from 15 organizations in each trial arm (n=30) will be purposively sampled. One-on-one semi-structured interviews will be conducted by telephone on their views about and their experiences with the evidence service they received, how helpful it was in their work, why it was helpful (or not helpful), what aspects were most and least helpful and why, and recommendations for next steps.
- Conditions
- Use of Research Evidence
- Being tested
- SHARE (Synthesized HIV/AIDS Research Evidence)
- Keywords
- Knowledge translation, Community based organizations, HIV/AIDS
- Medical subject headings
- Acquired Immunodeficiency Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
SHARE (Synthesized HIV/AIDS Research Evidence)Other
SHARE (Synthesized HIV/AIDS Research Evidence) consists of several components:
- an online searchable database of HIV-relevant systematic reviews;
- monthly email updates highlighting new reviews;
- access to user-friendly summaries produced by us or by others (when available);
- links to scientific abstracts;
- peer relevance assessments, which involves periodic requests to complete a brief assessment of how useful the information in the newly added review is with the average score posted once an assessment is completed;
- an interface for participants to leave comments in the records of systematic reviews in the database;
- links to full-text articles (when publicly available); and
- access to worksheets that help CBOs find and use research evidence
| Study group | Role | What they receive |
|---|---|---|
| Full-serve evidence service | Experimental | The full-serve evidence service consists of:
1. an online searchable database of HIV-relevant systematic reviews;
2. monthly email updates highlighting new reviews;
3. access to user-friendly summaries produced by us or by others (when available);
4. links to scientific abstracts;
5. peer relevance assessments, which involves periodic requests to complete a brief assessment of how useful the information in the newly added review is with the average score posted once an assessment is completed;
6. an interface for participants to leave comments in the records of systematic reviews in the database;
7. links to full-text articles (when publicly available); and
8. access to worksheets that help CBOs find and use research evidence Receives: Other: SHARE (Synthesized HIV/AIDS Research Evidence) |
| Self-serve evidence service | Active comparator | Organizations allocated to the control group will only be provided website access to a listing of systematic reviews that are organized by year of publication with links to the record on PubMed (or another publicly available source when not available on PubMed) and access to worksheets that help community-based organizations find and use research evidence. Receives: Other: SHARE (Synthesized HIV/AIDS Research Evidence) |
What is being measured
The primary outcome is the main question the study is designed to answer.
number of logins/month/organization
The investigators will track utilization of the evidence service at the organizational level by calculating the mean number of logins/month/organization (the total organizational logins/month will be averaged across the number of users from each organization).
Measured: 6 months
Secondary outcomes (1)
Intention to use research evidence
The investigators will use the theory of planned behaviour to measure participants' intention to use research. Using a manual designed to construct measures based on the theory, colleagues have developed and sought preliminary feedback on a data-collection instrument by first assessing face validity through interviews with key informants and then pilot testing it with 28 policymakers and researchers who completed it after participating in a knowledge translation intervention. In addition, colleagues found the data-collection instrument to have moderate test-retest reliability.
Measured: Baseline and follow-up (after delivery of 6-month intervnetion)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Dec 2010 (estimated)
- Study startMar 2011
- Primary completionSep 2012 (estimated)
- Study completionJan 2013 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Use of Research EvidenceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 58 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ontario HIV Treatment Network
- Sponsor type
- Research network
- Collaborators
- McMaster University
- Responsible party
- Principal investigator, Michael G. Wilson, Ontario HIV Treatment Network
- Investigators
- Michael G Wilson, PhD, Principal investigator, McMaster University; Ontario HIV Treatment NetworkJohn N Lavis, MD, PhD, Principal investigator, McMaster University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01257724
- Sponsor's protocol ID
- HHS/FHS REB 10-268
- Status last verified
- Dec 2011
- First submitted
- 9 Dec 2010
- Last updated
- 15 Dec 2011
- Results posted
- No
- Data monitoring committee
- No
Publications
Wilson MG, Lavis JN, Grimshaw JM, Haynes RB, Bekele T, Rourke SB. Effects of an evidence service on community-based AIDS service organizations' use of research evidence: a protocol for a randomized controlled trial. Implement Sci. 2011 May 27;6:52. doi: 10.1186/1748-5908-6-52.
PubMed 21619622
Study at a glance
From the registry record, last updated by the sponsor on 15 Dec 2011. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence: A Protocol for a Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT01257724
- Acronym / sponsor ID
- HHS/FHS REB 10-268
- Conditions
- Use of Research Evidence
- Keywords
- Knowledge translation, Community based organizations, HIV/AIDS
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 58 participants (actual)
- Lead sponsor
- Ontario HIV Treatment NetworkResearch network
- Collaborators
- McMaster University
- Study start
- Mar 2011
- Primary completion
- Sep 2012 (estimated)
- Study completion
- Jan 2013 (estimated)
- First posted
- 10 Dec 2010 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators have developed an online database called 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is designed to support the use of research evidence by those working in the HIV/AIDS sector. This study will evaluate whether a "full-serve" version of SHARE increases the use of research evidence by community-based organizations as compared to a "self-serve" version. The "full-serve" version of SHARE consists of several components: 1) an online searchable database of synthesized research evidence relevant to HIV/AIDS , 2) periodic emailed updates, 3) access to user-friendly summaries and 4) peer-relevance assessments. The self-serve version consists only of a listing of relevant synthesized research evidence . The investigators will also interview participants in the study to obtain feedback about SHARE, how helpful it was in their work, why it was helpful (or not helpful), what aspects were most and least helpful and why, and recommendations for improving it.
Detailed description
Background To support the use of research evidence by community-based organizations the investigators have developed 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is an evidence service for those working in the HIV sector. SHARE consists of several components: 1) an online searchable database of HIV-relevant systematic reviews (retrievable based on a taxonomy of topics related to HIV/AIDS and open text search), 2) periodic email updates, 3) access to user-friendly summaries, and 4) peer relevance assessments. The objective is to evaluate whether this "full serve" evidence service increases the use of research evidence by community-based organizations as compared to a "self-serve" evidence service.
Methods/design The investigators will conduct a two-arm randomized controlled trial (RCT), along with a follow-up qualitative process study to explore the findings in greater depth. All community-based organizations affiliated with Canadian AIDS Society (n=120) will be invited to participate and will be randomized to receive either the "full-serve" version of SHARE or the "self-serve" version (a listing of relevant systematic reviews with links to records on PubMed and worksheets that help community-based organizations find and use research evidence) using a simple randomized design. All management and staff from each organization will be provided access to the version of SHARE that their organization is allocated to. The trial duration will be 10 months (two-month baseline period, six-month intervention period, and two month cross-over period), the primary outcome measure will be the mean number of logins/month/organization (averaged across the number of users from each organization) between baseline and the end of the intervention period and the secondary outcome will be intention to use research evidence as measured by a survey administered to one key decision-maker from each organization. For the qualitative study, one key organizational decision-maker from 15 organizations in each trial arm (n=30) will be purposively sampled. One-on-one semi-structured interviews will be conducted by telephone on their views about and their experiences with the evidence service they received, how helpful it was in their work, why it was helpful (or not helpful), what aspects were most and least helpful and why, and recommendations for next steps.
Study design
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Full-serve evidence service | Experimental | Other: SHARE (Synthesized HIV/AIDS Research Evidence)The full-serve evidence service consists of: 1. an online searchable database of HIV-relevant systematic reviews; 2. monthly email updates highlighting new reviews; 3. access to user-friendly summaries produced by us or by others (when available); 4. links to scientific abstracts; 5. peer relevance assessments, which involves periodic requests to complete a brief assessment of how useful the information in the newly added review is with the average score posted once an assessment is completed; 6. an interface for participants to leave comments in the records of systematic reviews in the database; 7. links to full-text articles (when publicly available); and 8. access to worksheets that help CBOs find and use research evidence |
| Self-serve evidence service | Active comparator | Other: SHARE (Synthesized HIV/AIDS Research Evidence)Organizations allocated to the control group will only be provided website access to a listing of systematic reviews that are organized by year of publication with links to the record on PubMed (or another publicly available source when not available on PubMed) and access to worksheets that help community-based organizations find and use research evidence. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (1 listed)
- We will include all community-based organizations affiliated with the Canadian AIDS Society and from relevant provincial HIV/AIDS networks in Canada.
Key exclusion criteria (1 listed)
- We will exclude organizations that do not have at least one key decision-maker who is comfortable participating and corresponding in English.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| SHARE (Synthesized HIV/AIDS Research Evidence)SHARE (Synthesized HIV/AIDS Research Evidence) consists of several components: 1. an online searchable database of HIV-relevant systematic reviews; 2. monthly email updates highlighting new reviews; 3. access to user-friendly summaries produced by us or by others (when available); 4. links to scientific abstracts; 5. peer relevance assessments, which involves periodic requests to complete a brief assessment of how useful the information in the newly added review is with the average score posted once an assessment is completed; 6. an interface for participants to leave comments in the records of systematic reviews in the database; 7. links to full-text articles (when publicly available); and 8. access to worksheets that help CBOs find and use research evidence | Other | Full-serve evidence service, Self-serve evidence service |
Primary outcome
number of logins/month/organization
Time frame: 6 months
The investigators will track utilization of the evidence service at the organizational level by calculating the mean number of logins/month/organization (the total organizational logins/month will be averaged across the number of users from each organization).
1 secondary outcome
Intention to use research evidence
Time frame: Baseline and follow-up (after delivery of 6-month intervnetion)
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Dec 2011.
- Derived from this study: PubMed 21619622Wilson MG, Lavis JN, Grimshaw JM, Haynes RB, Bekele T, Rourke SB. Effects of an evidence service on community-based AIDS service organizations' use of research evidence: a protocol for a randomized controlled trial. Implement Sci. 2011 May 27;6:52. doi: 10.1186/1748-5908-6-52.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Michael G Wilson, PhD principal investigator
McMaster University; Ontario HIV Treatment Network
John N Lavis, MD, PhD principal investigator
McMaster University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing SHARE (Synthesized HIV/AIDS Research Evidence) in people with Use of Research Evidence, run by Ontario HIV Treatment Network at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 15 Dec 2011. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
number of logins/month/organization (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01257724, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Dec 2011.