Visual Sensitivity in NewbornsNCT01330537
Exploring the Visual Sensitivity for Topological Properties in Newborn Infants
An observational study of Visual Sensitivity in Newborns, run by China Medical University Hospital at 1 site in Taiwan.
Trial summary
The topological perception theory proposed a precise description for how one organizes the visual world that eliminates the vagueness of subjective phenomenology. In addition, the topological theory challenges the dominant computational view on the part-to-whole hierarchy of visual information processing. Read more about this study
- Who is it for?
- Ages 3 hours to 14 daysHealthy volunteers can take part
- Conditions the study is for
- Visual Sensitivity in Newborns
- How many people
- 80 participants
- Where
- 1 siteTaiwan
- Study dates
- Apr 2011to Mar 2013
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 3 hours to 14 days
- All sexes
- Healthy volunteers accepted
- Child
Study population: full-term and healthy newborns
Who may be able to join
- full-term and healthy newborns
Who cannot join
- Eye illnesses or other physical problems
Trial locations and contacts
1 site in 1 country.
About this study
The topological perception theory proposed a precise description for how one organizes the visual world that eliminates the vagueness of subjective phenomenology. In addition, the topological theory challenges the dominant computational view on the part-to-whole hierarchy of visual information processing. Lines of evidence from adult psychophysics, brain imaging data, and even honeybee's behavior have supported the notion that the global topological properties are the very primitives of visual representation. However, the question of how the sensitivity to topological properties originates during development has not been explored much. In a previous study, the investigators found that 2- to 6 month old infants could reliably discriminate stimuli based on topological differences, but failed to do so based on geometric differences. Using familiarization/novelty preference procedure, the present study intends to explore the visual sensitivity for topological properties in newborn infants. Experiment 1 focuses on whether neonates can discriminate a disk (no hole) and a ring (with a hole) that are topologically different, and/or a disk (no hole) and a triangle (no hole) that are geometrically different. Experiment 2 focuses on whether neonates can detect a change in the number of holes and/or the size of the hole. If newborn infants are only sensitive to topological properties and not to geometric properties, this will be a strong proof for the claim that topological property is the very "primitive" visual representation at empirical as well as theoretical level.
- Conditions
- Visual Sensitivity in Newborns
- Keywords
- perceptual development, topological perception theory, familiarization/novelty preference method, Discriminate a disk and a ring (topologically different),, Discriminate a disk and a triangle (geometrically different), Detect a change in the number of holes, Detect the size of the hole
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Apr 2011 (estimated)
- Study startApr 2011
- Primary completionFeb 2013
- Study completionMar 2013
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Visual Sensitivity in NewbornsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 80 participants (actual)
Sponsor and investigators
- Lead sponsor
- China Medical University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sarina Hui-Lin Chien, China Medical University, China
- Investigators
- Sarina Hui-Lin Chien, PhD, Principal investigator, Graduate Institute of Neural and Cognitive Sciences, China Medical University, TaiwanBai-Horng Su, M.D., Principal investigator, China Medical University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01330537
- Sponsor's protocol ID
- DMR100-IRB-019
- Status last verified
- Jan 2021
- First submitted
- 5 Apr 2011
- Last updated
- 28 Jan 2021
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Jan 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Exploring the Visual Sensitivity for Topological Properties in Newborn Infants
- ClinicalTrials.gov ID
- NCT01330537
- Acronym / sponsor ID
- DMR100-IRB-019
- Conditions
- Visual Sensitivity in Newborns
- Keywords
- perceptual development, topological perception theory, familiarization/novelty preference method, Discriminate a disk and a ring (topologically different),, Discriminate a disk and a triangle (geometrically different), Detect a change in the number of holes, Detect the size of the hole
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 80 participants (actual)
- Lead sponsor
- China Medical University HospitalUniversity, hospital or other
- Study start
- Apr 2011
- Primary completion
- Feb 2013 (actual)
- Study completion
- Mar 2013 (actual)
- First posted
- 7 Apr 2011 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The topological perception theory proposed a precise description for how one organizes the visual world that eliminates the vagueness of subjective phenomenology. In addition, the topological theory challenges the dominant computational view on the part-to-whole hierarchy of visual information processing. Lines of evidence from adult psychophysics, brain imaging data, and even honeybee's behavior have supported the notion that the global topological properties are the very primitives of visual representation. However, the question of how the sensitivity to topological properties originates during development has not been explored much. In a previous study, the investigators found that 2- to 6 month old infants could reliably discriminate stimuli based on topological differences, but failed to do so based on geometric differences. Using familiarization/novelty preference procedure, the present study intends to explore the visual sensitivity for topological properties in newborn infants. Experiment 1 focuses on whether neonates can discriminate a disk (no hole) and a ring (with a hole) that are topologically different, and/or a disk (no hole) and a triangle (no hole) that are geometrically different. Experiment 2 focuses on whether neonates can detect a change in the number of holes and/or the size of the hole. If newborn infants are only sensitive to topological properties and not to geometric properties, this will be a strong proof for the claim that topological property is the very "primitive" visual representation at empirical as well as theoretical level.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 3 hours to 14 days
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
- Study population
- full-term and healthy newborns
Key inclusion criteria (1 listed)
- full-term and healthy newborns
Key exclusion criteria (1 listed)
- Eye illnesses or other physical problems
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Jan 2021.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Sarina Hui-Lin Chien, PhD principal investigator
Graduate Institute of Neural and Cognitive Sciences, China Medical University, Taiwan
Bai-Horng Su, M.D. principal investigator
China Medical University Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Visual Sensitivity in Newborns, run by China Medical University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Jan 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jan 2021.