HealthyYCFRNCT01362166
Frequency Response of the Foot-Yangming Stomach Channel: Zu-San-Li and Xian-Gu
An observational study of Healthy, run by China Medical University Hospital at 1 site in Taiwan.
Trial summary
The main purpose of this study is to detect the frequency response in the electric wave transmission through the channels inside human body. With the electric signals in different frequencies, analyzed by the digital signal processing technique, the adaptability of the channel for different frequencies may be… Read more about this study
- Who is it for?
- Ages 20 to 35 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy
- How many people
- 30 participants
- Where
- 1 siteTaiwan
- Study dates
- May 2011to not given
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 35 years
- Men only
- Healthy volunteers accepted
- Adult
Study population: community sample
Who may be able to join
- have never got myocardial infarction, heart failure, or any other heavy diseases
- in normal mental state, can match with the researcher
- would like to obey the experiment 24-hour related rules
- sign the written agreement
Who cannot join
- The one who has arrhythmia, or is equipped with the heart stanza machine.
- Get myocardial infarction, heart failure, and the other heavy diseases
- The mental state is unsteady.
- Female.
- Does not sign the written agreement.
Trial locations and contacts
1 site in 1 country.
Taiwan1 site, 1 recruiting
- Recruiting
China Medical University
Taichung, 40402
Bin-Han Lin, MD, 886-953888053, programhunt@yahoo.com.tw
Fun-jou Chen, Prof., 886-4-22053366 ext. 3503, fjchen@mail.cmu.edu.tw
About this study
Official title: With Different Frequency Electric Signals Study the Frequency Response of the Foot-Yangming Stomach Channel: Zu-San-Li and Xian-Gu
The main purpose of this study is to detect the frequency response in the electric wave transmission through the channels inside human body. With the electric signals in different frequencies, analyzed by the digital signal processing technique, the adaptability of the channel for different frequencies may be revealed. With this study there will be a feasible connection between the physiological signals and the channel theory in Chinese medicine, and the basis of the physiological signals can be drew out for the description of the internal organs, the strong or weak, the truth or falsity.
The Zu-San-Li is the open acupoint on foot-Yangming channel, the stomach channel. Qi, the main concept in TCM, will flow from the open acupoint to go into deep internal organs. Xian-Gu is another Yu acupoint on foot-Yangming channel. The inborn original Qi flows from the Yu acupoint infuse into blood vessels. So in this study the investigators will take these two acupoints for the acupuncture. Since the direction of the channel is from Zu-San-Li to Xian-Gu, the investigators pick Zu-San-Li as the input and Xian-Gu the output for the electrical signals.
Read more
For this experiment, the investigators planned enrolling 30 male sub-healthy volunteers, aged in 20-35 years old, to finish the whole experiment procedures.
After the acupuncture, the electric signals of different modes will be input from the subject's open acupoint (Zu-San-Li), and measure the frequency respond voltage from the output acupoint (Xian-Gu).
Each subject must complete the acupuncture of Zu-San-Li and Xian-Gu, and be input 5 sets of the electric signals of different modes two times on the trial. The variety conditions of the wave form and electric voltage will be recorded and measured respectively.
The investigators plan to obtain the data in six months, and complete the data analysis and sorting in two months.
- Conditions
- Healthy
- Keywords
- Chinese medicine, channel, acupuncture, ZuSanLi, XianGu, frequency response, resonance, male volunteer, aged within 20-35 years old
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 May 2011 (estimated)
- Study startMay 2011
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (11)Papers the sponsor has linked to this study.
- Other trials for HealthyStudies of the same condition, open and under way.
- More trials run by China Medical University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- China Medical University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- China Medical University, China
- Investigators
- Fun-jou Chen, Prof., Study director, China Medical University, China
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01362166
- Sponsor's protocol ID
- DMR100-IRB-034
- Acronym
- YCFR
- Status last verified
- May 2011
- First submitted
- 26 May 2011
- Last updated
- 30 May 2011
- Results posted
- No
- Data monitoring committee
- Yes
Publications
Dhond RP, Yeh C, Park K, Kettner N, Napadow V. Acupuncture modulates resting state connectivity in default and sensorimotor brain networks. Pain. 2008 Jun;136(3):407-418. doi: 10.1016/j.pain.2008.01.011. Epub 2008 Mar 11.
PubMed 18337009Sakai S, Hori E, Umeno K, Kitabayashi N, Ono T, Nishijo H. Specific acupuncture sensation correlates with EEGs and autonomic changes in human subjects. Auton Neurosci. 2007 May 30;133(2):158-69. doi: 10.1016/j.autneu.2007.01.001. Epub 2007 Feb 22.
PubMed 17321222Streitberger K, Steppan J, Maier C, Hill H, Backs J, Plaschke K. Effects of verum acupuncture compared to placebo acupuncture on quantitative EEG and heart rate variability in healthy volunteers. J Altern Complement Med. 2008 Jun;14(5):505-13. doi: 10.1089/acm.2007.0552.
PubMed 18537467Napadow V, Dhond RP, Purdon P, Kettner N, Makris N, Kwong KK, Hui KK. Correlating acupuncture FMRI in the human brainstem with heart rate variability. Conf Proc IEEE Eng Med Biol Soc. 2005;2005:4496-9. doi: 10.1109/IEMBS.2005.1615466.
PubMed 17281236Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996 Mar;17(3):354-81. No abstract available.
PubMed 8737210Guzzetti S, Piccaluga E, Casati R, Cerutti S, Lombardi F, Pagani M, Malliani A. Sympathetic predominance in essential hypertension: a study employing spectral analysis of heart rate variability. J Hypertens. 1988 Sep;6(9):711-7. doi: 10.1097/00004872-198809000-00004.
PubMed 3183374Lishner M, Akselrod S, Avi VM, Oz O, Divon M, Ravid M. Spectral analysis of heart rate fluctuations. A non-invasive, sensitive method for the early diagnosis of autonomic neuropathy in diabetes mellitus. J Auton Nerv Syst. 1987 May;19(2):119-25. doi: 10.1016/0165-1838(87)90005-1.
PubMed 3598051Axelrod S, Lishner M, Oz O, Bernheim J, Ravid M. Spectral analysis of fluctuations in heart rate: an objective evaluation of autonomic nervous control in chronic renal failure. Nephron. 1987;45(3):202-6. doi: 10.1159/000184117.
PubMed 3574569Buchman TG, Stein PK, Goldstein B. Heart rate variability in critical illness and critical care. Curr Opin Crit Care. 2002 Aug;8(4):311-5. doi: 10.1097/00075198-200208000-00007.
PubMed 12386491Cashion AK, Holmes SL, Arheart KL, Acchiardo SR, Hathaway DK. Heart rate variability and mortality in patients with end stage renal disease. Nephrol Nurs J. 2005 Mar-Apr;32(2):173-84.
PubMed 15889802Ryan C, Hollenberg M, Harvey DB, Gwynn R. Impaired parasympathetic responses in patients after myocardial infarction. Am J Cardiol. 1976 Jun;37(7):1013-8. doi: 10.1016/0002-9149(76)90417-3.
PubMed 1274861
Study at a glance
From the registry record, last updated by the sponsor on 30 May 2011. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- With Different Frequency Electric Signals Study the Frequency Response of the Foot-Yangming Stomach Channel: Zu-San-Li and Xian-Gu
- ClinicalTrials.gov ID
- NCT01362166
- Acronym / sponsor ID
- YCFR / DMR100-IRB-034
- Conditions
- Healthy
- Keywords
- Chinese medicine, channel, acupuncture, ZuSanLi, XianGu, frequency response, resonance, male volunteer
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- China Medical University HospitalUniversity, hospital or other
- Collaborators
- China Medical University, China
- Study start
- May 2011
- First posted
- 30 May 2011 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main purpose of this study is to detect the frequency response in the electric wave transmission through the channels inside human body. With the electric signals in different frequencies, analyzed by the digital signal processing technique, the adaptability of the channel for different frequencies may be revealed. With this study there will be a feasible connection between the physiological signals and the channel theory in Chinese medicine, and the basis of the physiological signals can be drew out for the description of the internal organs, the strong or weak, the truth or falsity.
The Zu-San-Li is the open acupoint on foot-Yangming channel, the stomach channel. Qi, the main concept in TCM, will flow from the open acupoint to go into deep internal organs. Xian-Gu is another Yu acupoint on foot-Yangming channel. The inborn original Qi flows from the Yu acupoint infuse into blood vessels. So in this study the investigators will take these two acupoints for the acupuncture. Since the direction of the channel is from Zu-San-Li to Xian-Gu, the investigators pick Zu-San-Li as the input and Xian-Gu the output for the electrical signals.
For this experiment, the investigators planned enrolling 30 male sub-healthy volunteers, aged in 20-35 years old, to finish the whole experiment procedures.
After the acupuncture, the electric signals of different modes will be input from the subject's open acupoint (Zu-San-Li), and measure the frequency respond voltage from the output acupoint (Xian-Gu).
Each subject must complete the acupuncture of Zu-San-Li and Xian-Gu, and be input 5 sets of the electric signals of different modes two times on the trial. The variety conditions of the wave form and electric voltage will be recorded and measured respectively.
The investigators plan to obtain the data in six months, and complete the data analysis and sorting in two months.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 20 to 35 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- community sample
Key inclusion criteria (4 listed)
- have never got myocardial infarction, heart failure, or any other heavy diseases
- in normal mental state, can match with the researcher
- would like to obey the experiment 24-hour related rules
- sign the written agreement
Key exclusion criteria (5 listed)
- The one who has arrhythmia, or is equipped with the heart stanza machine.
- Get myocardial infarction, heart failure, and the other heavy diseases
- The mental state is unsteady.
- Female.
- Does not sign the written agreement.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 May 2011.
- Results publication: PubMed 18337009Dhond RP, Yeh C, Park K, Kettner N, Napadow V. Acupuncture modulates resting state connectivity in default and sensorimotor brain networks. Pain. 2008 Jun;136(3):407-418. doi: 10.1016/j.pain.2008.01.011. Epub 2008 Mar 11.
- Results publication: PubMed 17321222Sakai S, Hori E, Umeno K, Kitabayashi N, Ono T, Nishijo H. Specific acupuncture sensation correlates with EEGs and autonomic changes in human subjects. Auton Neurosci. 2007 May 30;133(2):158-69. doi: 10.1016/j.autneu.2007.01.001. Epub 2007 Feb 22.
- Results publication: PubMed 18537467Streitberger K, Steppan J, Maier C, Hill H, Backs J, Plaschke K. Effects of verum acupuncture compared to placebo acupuncture on quantitative EEG and heart rate variability in healthy volunteers. J Altern Complement Med. 2008 Jun;14(5):505-13. doi: 10.1089/acm.2007.0552.
- Results publication: PubMed 17281236Napadow V, Dhond RP, Purdon P, Kettner N, Makris N, Kwong KK, Hui KK. Correlating acupuncture FMRI in the human brainstem with heart rate variability. Conf Proc IEEE Eng Med Biol Soc. 2005;2005:4496-9. doi: 10.1109/IEMBS.2005.1615466.
- Results publication: PubMed 8737210Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996 Mar;17(3):354-81. No abstract available.
- Results publication: PubMed 3183374Guzzetti S, Piccaluga E, Casati R, Cerutti S, Lombardi F, Pagani M, Malliani A. Sympathetic predominance in essential hypertension: a study employing spectral analysis of heart rate variability. J Hypertens. 1988 Sep;6(9):711-7. doi: 10.1097/00004872-198809000-00004.
- Results publication: PubMed 3598051Lishner M, Akselrod S, Avi VM, Oz O, Divon M, Ravid M. Spectral analysis of heart rate fluctuations. A non-invasive, sensitive method for the early diagnosis of autonomic neuropathy in diabetes mellitus. J Auton Nerv Syst. 1987 May;19(2):119-25. doi: 10.1016/0165-1838(87)90005-1.
- Results publication: PubMed 3574569Axelrod S, Lishner M, Oz O, Bernheim J, Ravid M. Spectral analysis of fluctuations in heart rate: an objective evaluation of autonomic nervous control in chronic renal failure. Nephron. 1987;45(3):202-6. doi: 10.1159/000184117.
- Results publication: PubMed 12386491Buchman TG, Stein PK, Goldstein B. Heart rate variability in critical illness and critical care. Curr Opin Crit Care. 2002 Aug;8(4):311-5. doi: 10.1097/00075198-200208000-00007.
- Results publication: PubMed 15889802Cashion AK, Holmes SL, Arheart KL, Acchiardo SR, Hathaway DK. Heart rate variability and mortality in patients with end stage renal disease. Nephrol Nurs J. 2005 Mar-Apr;32(2):173-84.
- Results publication: PubMed 1274861Ryan C, Hollenberg M, Harvey DB, Gwynn R. Impaired parasympathetic responses in patients after myocardial infarction. Am J Cardiol. 1976 Jun;37(7):1013-8. doi: 10.1016/0002-9149(76)90417-3.
Related trials for Healthy
Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Physical Activity, Body Image
Not yet recruitingPhase 1
A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
Atopic Dermatitis
Recruiting
Colon-delivered Riboflavin and Gut Microbiota Composition
Microbiome Dysbiosis, Gut Health
Not yet recruiting
Neuroergonomic Analysis of a Brain-Computer Interface Device (BCI)
Healthy Volunteers - Male and Female
RecruitingPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy Volunteer, Atopic Dermatitis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Fun-jou Chen, Prof. study director
China Medical University, China
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Healthy, run by China Medical University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 30 May 2011. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Bin-han Lin, M.D. (886-953888053, programhunt@yahoo.com.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01362166, which also lists 11 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 May 2011.