ArthritisWork ItNCT01387100
A Modified Rehabilitation Intervention for Working Persons With Arthritis
A study testing Vocational Rehabilitation Intervention in people with Arthritis, run by Boston University Charles River Campus at 1 site in United States.
Trial summary
The purpose of this study is to explore the effects of a brief vocational rehabilitation intervention on individuals with arthritis who are concerned about their ability to remain employed. Read more about this study
- Who is it for?
- Ages 25 to 63 years
- Conditions the study is for
- Arthritis
- What is being tested?
- Vocational Rehabilitation Intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 300 participants
- Where
- 1 siteUnited States
- Study dates
- Jun 2011to Dec 2016
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 63 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Live or work in eastern Massachusetts
- Age 25-63 years
- Risk of work loss due to arthritis
- Arthritis
- Chronic back pain
- Currently employed
Who cannot join
- Unemployed
- No arthritis
Trial locations and contacts
1 site in 1 country.
United States1 site
Boston University, Sargent College of Health and Rehabilitation Sciences
Boston, Massachusetts, 02215
About this study
Official title: Efficacy of a Modified Vocational Rehabilitation Intervention for Work Disability
The purpose of this study is to explore the effects of a brief vocational rehabilitation intervention on individuals with arthritis who are concerned about their ability to remain employed.
- Conditions
- Arthritis
- Being tested
- Vocational Rehabilitation Intervention
- Keywords
- supportive employment, vocational rehabilitation
- Medical subject headings
- Arthritis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Vocational Rehabilitation InterventionBehavioural
Physical or occupational therapist will deliver a vocational rehabilitation intervention using the Work Experience Survey for Persons with Rheumatic Conditions (WES-RC) assessment tool to assess subject's health and vocational background as well as work barriers.
| Study group | Role | What they receive |
|---|---|---|
| Physical Therapist/Occupational Therapist Intervention | Experimental | This group will be assigned a physical therapist or occupational therapist to meet with followed by 2 phone consultations. Receives: Behavioral: Vocational Rehabilitation Intervention |
| Control | No intervention | This is the control group. This group will not receive the vocational rehabilitation intervention from an occupational or physical therapist. They will receive written information regarding job accommodations and disability advocacy. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in work status
Work limitation will be assessed using the Work Limitation Questionnaire, a tool developed to assess limitation in ability to work due to health.
Measured: Baseline, 6, 12, 24 month follow up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Jul 2011 (estimated)
- Study startJun 2011
- Primary completionDec 2015
- Study completionDec 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for ArthritisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 300 participants (actual)
Sponsor and investigators
- Lead sponsor
- Boston University Charles River Campus
- Sponsor type
- University, hospital or other
- Collaborators
- U.S. Department of Education
- Responsible party
- Sponsor
- Investigators
- Julie Keysor, PhD, Principal investigator, Boston University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01387100
- Sponsor's protocol ID
- H133B100003-1
- Acronym
- Work It
- Status last verified
- Apr 2016
- First submitted
- 23 Jun 2011
- Last updated
- 24 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
Publications
AlHeresh R, Vaughan MW, Brenner IH, Keysor J. Recruitment cost and outcomes for an arthritis work disability prevention randomized clinical trial: The Work It study. Contemp Clin Trials Commun. 2021 Nov 12;24:100862. doi: 10.1016/j.conctc.2021.100862. eCollection 2021 Dec.
PubMed 34825102Keysor JJ, LaValley MP, Brown C, Felson DT, AlHeresh RA, Vaughan MW, Yood R, Reed JI, Allaire SJ. Efficacy of a Work Disability Prevention Program for People with Rheumatic and Musculoskeletal Conditions: A Single-Blind Parallel-Arm Randomized Controlled Trial. Arthritis Care Res (Hoboken). 2018 Jul;70(7):1022-1029. doi: 10.1002/acr.23423. Epub 2018 Apr 25.
PubMed 28941189
Study at a glance
From the registry record, last updated by the sponsor on 24 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of a Modified Vocational Rehabilitation Intervention for Work Disability
- ClinicalTrials.gov ID
- NCT01387100
- Acronym / sponsor ID
- Work It / H133B100003-1
- Conditions
- Arthritis
- Keywords
- supportive employment, vocational rehabilitation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 300 participants (actual)
- Lead sponsor
- Boston University Charles River CampusUniversity, hospital or other
- Collaborators
- U.S. Department of Education
- Study start
- Jun 2011 (actual)
- Primary completion
- Dec 2015 (actual)
- Study completion
- Dec 2016 (actual)
- First posted
- 4 Jul 2011 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to explore the effects of a brief vocational rehabilitation intervention on individuals with arthritis who are concerned about their ability to remain employed.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Physical Therapist/Occupational Therapist Intervention | Experimental | Behavioral: Vocational Rehabilitation InterventionThis group will be assigned a physical therapist or occupational therapist to meet with followed by 2 phone consultations. |
| Control | No intervention | –This is the control group. This group will not receive the vocational rehabilitation intervention from an occupational or physical therapist. They will receive written information regarding job accommodations and disability advocacy. |
Who may qualify
- Ages
- 25 to 63 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Live or work in eastern Massachusetts
- Age 25-63 years
- Risk of work loss due to arthritis
- Arthritis
- Chronic back pain
Key exclusion criteria (2 listed)
- Unemployed
- No arthritis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Vocational Rehabilitation InterventionPhysical or occupational therapist will deliver a vocational rehabilitation intervention using the Work Experience Survey for Persons with Rheumatic Conditions (WES-RC) assessment tool to assess subject's health and vocational background as well as work barriers. | Behavioural | Physical Therapist/Occupational Therapist Intervention |
Primary outcome
Change in work status
Time frame: Baseline, 6, 12, 24 month follow up
Work limitation will be assessed using the Work Limitation Questionnaire, a tool developed to assess limitation in ability to work due to health.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jul 2026.
- Derived from this study: PubMed 34825102AlHeresh R, Vaughan MW, Brenner IH, Keysor J. Recruitment cost and outcomes for an arthritis work disability prevention randomized clinical trial: The Work It study. Contemp Clin Trials Commun. 2021 Nov 12;24:100862. doi: 10.1016/j.conctc.2021.100862. eCollection 2021 Dec.
- Derived from this study: PubMed 28941189Keysor JJ, LaValley MP, Brown C, Felson DT, AlHeresh RA, Vaughan MW, Yood R, Reed JI, Allaire SJ. Efficacy of a Work Disability Prevention Program for People with Rheumatic and Musculoskeletal Conditions: A Single-Blind Parallel-Arm Randomized Controlled Trial. Arthritis Care Res (Hoboken). 2018 Jul;70(7):1022-1029. doi: 10.1002/acr.23423. Epub 2018 Apr 25.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Julie Keysor, PhD principal investigator
Boston University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Vocational Rehabilitation Intervention in people with Arthritis, run by Boston University Charles River Campus at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in work status (time frame: Baseline, 6, 12, 24 month follow up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01387100, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jul 2026.