Physical ActivityNCT01475448
Long Distance Running Training by Older Adults
A study testing Long distance training and Walking training in people with Physical Activity and Aging, run by University of Sao Paulo at 1 site in Brazil.
Trial summary
The goal of this project is to understand the effect of regular practice of long distance running on the posture and movement control of older adults. For such, the investigators will conduct an experiment with longitudinal design where sedentary elderly individuals will be trained in long distance running for about 4… Read more about this study
- Who is it for?
- Ages 60 to 85 yearsHealthy volunteers can take part
- Conditions the study is for
- Physical Activity, Aging
- What is being tested?
- Long distance training and Walking training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 siteBrazil
- Study dates
- Jan 2012to Oct 2012
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 to 85 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Sedentary
- Independent bipedal locomotion
Who cannot join
- Inapt for practicing physical activity
- Severe alteration of the muscle-skeletal system
- Cognitive or neurological deficit
- Use of orthosis for locomotion
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Long Distance Running Training on the Posture and Movement Control of Sedentary Older Adults
The goal of this project is to understand the effect of regular practice of long distance running on the posture and movement control of older adults.
For such, the investigators will conduct an experiment with longitudinal design where sedentary elderly individuals will be trained in long distance running for about 4 months.
Read the detailed description
In a study the investigators conducted about elderly runners, the main observed difference by the first time was that elderly individuals present greater foot abduction (toe-out) during running than young adults. This alteration has been observed in elderly individuals in general during walking, and identified as a protective mechanism to not overload the medial compartment of the knee joint. It is also known that elderly individuals present a different joint torque distribution in the lower limbs during walking in comparison with young adults. However, it's not known the relation between the movement patterns, particularly the foot abduction pattern, and the mechanical load on the knee joint during running by elderly individuals and neither the longitudinal effect of running practice on this relation and on the mechanical joint load distribution. Another unknown aspect is the actual effect of the running practice on the posture control of elderly individuals.
With this project, the investigators want to understand why elderly individuals change their movement pattern during running, to determine for the same subjects if this altered pattern is also present during walking and standing, and to determine the effect of running practice on the elderly posture control. Our hypotheses are that the strategy of greater foot abduction is present in all movement tasks and that the use of this strategy is related to the integrity of the knee joint, even considering the highly active elderly individuals and that the practice of running contributes for a better postural control in this population.
These findings will contribute for a greater understanding of the benefits of the practice of running and the adaptations developed by the elderly runners and in this way to contribute for the prescription of this activity to the elderly population.
- Conditions
- Physical Activity, Aging
- Being tested
- Long distance training, Walking training
- Keywords
- biomechanics, motor control, movement, walking, running, sedentarism, joint moment
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Long distance trainingOther
Long distance training during four months, 3 times per week
Walking trainingOther
Walking training during four months, three times per week
| Study group | Role | What they receive |
|---|---|---|
| Sedentary older adults - running | Experimental | Sedentary older adults (60 years old or more) recruited from local community Receives: Other: Long distance training |
| Sedentary older adults - walking | Active comparator | Sedentary older adults (60 years old or more) recruited from local community Receives: Other: Walking training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change from baseline of posture and movement patterns at 16 weeks
biomechanical and physiological measures of the posture and movement patterns
Measured: Two weeks before and two weeks after the training for sixteen months
Secondary outcomes (3)
Change from baseline of mechanical joint moments estimated by inverse dynamics at 16 weeks
Estimated joint moments by inverse dynamics at the ankle, knee, and hip joints during the support phase of walking and running
Measured: Two weeks before and two weeks after the training for four months
Change from baseline of muscle activity measured by surface electromyography of selected muscles of the lower limb at 16 weeks
Electromyographic activity of lower limb muscles during walking and running
Measured: Two weeks before and two weeks after the training for four months
Change from baseline of body sway measured by estabilography with a force plate during standing at 16 weeks
Measurements of balance control during quiet and unconstrained standing using a force platform.
Measured: Two weeks before and two weeks after the training for four months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Nov 2011 (estimated)
- Study startJan 2012
- Primary completionAug 2012
- Study completionOct 2012
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Physical ActivityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 34 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Sao Paulo
- Sponsor type
- University, hospital or other
- Collaborators
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Responsible party
- Principal investigator, Marcos Duarte, University of Sao Paulo
- Investigators
- Marcos Duarte, Principal investigator, Federal University of ABC
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01475448
- Sponsor's protocol ID
- FR-262790
- Status last verified
- Nov 2011
- First submitted
- 3 Nov 2011
- Last updated
- 5 May 2015
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 May 2015. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Long Distance Running Training on the Posture and Movement Control of Sedentary Older Adults
- ClinicalTrials.gov ID
- NCT01475448
- Acronym / sponsor ID
- FR-262790
- Conditions
- Physical Activity, Aging
- Keywords
- biomechanics, motor control, movement, walking, running, sedentarism, joint moment
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 34 participants (actual)
- Lead sponsor
- University of Sao PauloUniversity, hospital or other
- Collaborators
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Study start
- Jan 2012
- Primary completion
- Aug 2012 (actual)
- Study completion
- Oct 2012 (actual)
- First posted
- 21 Nov 2011 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this project is to understand the effect of regular practice of long distance running on the posture and movement control of older adults.
For such, the investigators will conduct an experiment with longitudinal design where sedentary elderly individuals will be trained in long distance running for about 4 months.
Detailed description
In a study the investigators conducted about elderly runners, the main observed difference by the first time was that elderly individuals present greater foot abduction (toe-out) during running than young adults. This alteration has been observed in elderly individuals in general during walking, and identified as a protective mechanism to not overload the medial compartment of the knee joint. It is also known that elderly individuals present a different joint torque distribution in the lower limbs during walking in comparison with young adults. However, it's not known the relation between the movement patterns, particularly the foot abduction pattern, and the mechanical load on the knee joint during running by elderly individuals and neither the longitudinal effect of running practice on this relation and on the mechanical joint load distribution. Another unknown aspect is the actual effect of the running practice on the posture control of elderly individuals.
With this project, the investigators want to understand why elderly individuals change their movement pattern during running, to determine for the same subjects if this altered pattern is also present during walking and standing, and to determine the effect of running practice on the elderly posture control. Our hypotheses are that the strategy of greater foot abduction is present in all movement tasks and that the use of this strategy is related to the integrity of the knee joint, even considering the highly active elderly individuals and that the practice of running contributes for a better postural control in this population.
These findings will contribute for a greater understanding of the benefits of the practice of running and the adaptations developed by the elderly runners and in this way to contribute for the prescription of this activity to the elderly population.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Sedentary older adults - running | Experimental | Other: Long distance trainingSedentary older adults (60 years old or more) recruited from local community |
| Sedentary older adults - walking | Active comparator | Other: Walking trainingSedentary older adults (60 years old or more) recruited from local community |
Who may qualify
- Ages
- 60 to 85 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Sedentary
- Independent bipedal locomotion
Key exclusion criteria (4 listed)
- Inapt for practicing physical activity
- Severe alteration of the muscle-skeletal system
- Cognitive or neurological deficit
- Use of orthosis for locomotion
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Long distance trainingLong distance training during four months, 3 times per week | Other | Sedentary older adults - running |
| Walking trainingWalking training during four months, three times per week | Other | Sedentary older adults - walking |
Primary outcome
Change from baseline of posture and movement patterns at 16 weeks
Time frame: Two weeks before and two weeks after the training for sixteen months
biomechanical and physiological measures of the posture and movement patterns
3 secondary outcomes
Change from baseline of mechanical joint moments estimated by inverse dynamics at 16 weeks
Time frame: Two weeks before and two weeks after the training for four months
Change from baseline of muscle activity measured by surface electromyography of selected muscles of the lower limb at 16 weeks
Time frame: Two weeks before and two weeks after the training for four months
Change from baseline of body sway measured by estabilography with a force plate during standing at 16 weeks
Time frame: Two weeks before and two weeks after the training for four months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 May 2015.
Related trials for Physical Activity
RecruitingPhase 1
Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency
Inherited Bone Marrow Failure Syndrome, Familial Platelet Disorder With Predisposition to Myeloid Malignancies
Active, not recruitingObservational study
A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis
Colitis, Ulcerative
RecruitingPhase 2
Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD
Chronic Kidney Disease
Not yet recruiting
Combined Versus Multicomponent Training in People With Chronic Kidney Disease Stages 3a and 3b
Chronic Kidney Disease Stage 3A, Chronic Kidney Disease Stage 3B
Not yet recruitingObservational study
A Study of Fatigue, Itching and Daily Activities in People With Primary Biliary Cholangitis Starting Elafibranor
Primary Biliary Cholangitis (PBC)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Marcos Duarte principal investigator
Federal University of ABC
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Long distance training and Walking training in people with Physical Activity and Aging, run by University of Sao Paulo at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 May 2015. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change from baseline of posture and movement patterns at 16 weeks (time frame: Two weeks before and two weeks after the training for sixteen months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 May 2015.