HIV PositiveMMC-1NCT01536899
Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
An observational study of HIV Positive and Marijuana Smoking, run by Wayne State University at 1 site in United States.
Trial summary
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients. Several alternative hypotheses will be evaluated in the proposed project: 1. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- HIV Positive, Marijuana Smoking
- How many people
- 119 participants
- Where
- 1 siteUnited States
- Study dates
- Feb 2012to Jun 2017
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: HIV positive and marijuana using volunteers
Who may be able to join
- Participants will be patients in the HIV clinic.
- Participants will have HIV.
- Participants will sign a single consent form.
- Participants will be marijuana users.
Who cannot join
- Participants who test negative for marijuana will be excluded.
- Volunteers who exhibit signs of drug intoxication or cognitive/mental impairment during the consent process will be excluded.
Trial locations and contacts
1 site in 1 country.
United States1 site
Wayne State University (HIV clinic, Tolan Park Medical Buiding)
Detroit, Michigan, 48201
About this study
Official title: Behavioral Economic Analysis of Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients.
Several alternative hypotheses will be evaluated in the proposed project:
- healthier patients may self-select marijuana use;
- marijuana use may be associated with consequences that create barriers to seeking healthcare;
- marijuana use may have medicinal value that reduces the need for such care.
Read the detailed description
The study will involve a total of 5 interviews with clinical research staff members, the total involvement will be for about 1 year.
The first interview will establish a baseline of current behaviors and health status; this will take about 3-4 hours. This interview will take place at the Tolan Park Medical Building, located at 3901 Chrysler Service Dr. The remaining 4 interviews - which will be shorter in length - will be conducted about 3, 6, 9, and 12 months after the baseline interview; each follow-up interview will take about 2 hours.The purpose of the 4 remaining interviews is to assess changes in behaviors and health status over time.
We will collect urine samples at each of the 5 interview sessions to assess health and illicit drug use.
- Conditions
- HIV Positive, Marijuana Smoking
- Keywords
- HIV positive, Medical Marijuana
- Medical subject headings
- HIV Seropositivity, Marijuana Smoking
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Feb 2012 (estimated)
- Study startFeb 2012
- Primary completionJun 2017
- Study completionJun 2017
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for HIV PositiveStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 119 participants (actual)
Sponsor and investigators
- Lead sponsor
- Wayne State University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Responsible party
- Principal investigator, Mark Greenwald, PhD, Wayne State University
- Investigators
- Mark Greenwald, PhD, Principal investigator, Wayne State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01536899
- Sponsor's protocol ID
- MMC-1
- Other IDs
- R01DA032678
- Acronym
- MMC-1
- Status last verified
- Apr 2018
- First submitted
- 16 Feb 2012
- Last updated
- 5 Apr 2018
- Results posted
- No
- Data monitoring committee
- No
Publications
Denha VA, Lundahl LH, Cohn JA, Greenwald MK, Woodcock EA. Longitudinal analysis of symptoms and healthcare utilization among daily cannabis-using persons living with HIV: impact of co-occurring cocaine use. J Cannabis Res. 2026 May 1;8(1):75. doi: 10.1186/s42238-026-00443-7.
PubMed 42067947Woodcock EA, Greenwald MK, Chen I, Feng D, Cohn JA, Lundahl LH. HIV chronicity as a predictor of hippocampal memory deficits in daily cannabis users living with HIV. Drug Alcohol Depend Rep. 2023 Sep 13;9:100189. doi: 10.1016/j.dadr.2023.100189. eCollection 2023 Dec.
PubMed 37736522
Study at a glance
From the registry record, last updated by the sponsor on 5 Apr 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Behavioral Economic Analysis of Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
- ClinicalTrials.gov ID
- NCT01536899
- Acronym / sponsor ID
- MMC-1 / MMC-1
- Conditions
- HIV Positive, Marijuana Smoking
- Keywords
- HIV positive, Medical Marijuana
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 119 participants (actual)
- Lead sponsor
- Wayne State UniversityUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Study start
- Feb 2012
- Primary completion
- Jun 2017 (actual)
- Study completion
- Jun 2017 (actual)
- First posted
- 22 Feb 2012 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients.
Several alternative hypotheses will be evaluated in the proposed project:
- healthier patients may self-select marijuana use;
- marijuana use may be associated with consequences that create barriers to seeking healthcare;
- marijuana use may have medicinal value that reduces the need for such care.
Detailed description
The study will involve a total of 5 interviews with clinical research staff members, the total involvement will be for about 1 year.
The first interview will establish a baseline of current behaviors and health status; this will take about 3-4 hours. This interview will take place at the Tolan Park Medical Building, located at 3901 Chrysler Service Dr. The remaining 4 interviews - which will be shorter in length - will be conducted about 3, 6, 9, and 12 months after the baseline interview; each follow-up interview will take about 2 hours.The purpose of the 4 remaining interviews is to assess changes in behaviors and health status over time.
We will collect urine samples at each of the 5 interview sessions to assess health and illicit drug use.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- HIV positive and marijuana using volunteers
Key inclusion criteria (4 listed)
- Participants will be patients in the HIV clinic.
- Participants will have HIV.
- Participants will sign a single consent form.
- Participants will be marijuana users.
Key exclusion criteria (2 listed)
- Participants who test negative for marijuana will be excluded.
- Volunteers who exhibit signs of drug intoxication or cognitive/mental impairment during the consent process will be excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Apr 2018.
- Derived from this study: PubMed 42067947Denha VA, Lundahl LH, Cohn JA, Greenwald MK, Woodcock EA. Longitudinal analysis of symptoms and healthcare utilization among daily cannabis-using persons living with HIV: impact of co-occurring cocaine use. J Cannabis Res. 2026 May 1;8(1):75. doi: 10.1186/s42238-026-00443-7.
- Derived from this study: PubMed 37736522Woodcock EA, Greenwald MK, Chen I, Feng D, Cohn JA, Lundahl LH. HIV chronicity as a predictor of hippocampal memory deficits in daily cannabis users living with HIV. Drug Alcohol Depend Rep. 2023 Sep 13;9:100189. doi: 10.1016/j.dadr.2023.100189. eCollection 2023 Dec.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Mark Greenwald, PhD principal investigator
Wayne State University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of HIV Positive and Marijuana Smoking, run by Wayne State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Apr 2018. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01536899, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Apr 2018.