Habitual AbortionNCT01644318
CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions
An observational study of Habitual Abortion, run by Ankara Education and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions Read more about this study
- Who is it for?
- Ages 20 to 40 years, women only
- Conditions the study is for
- Habitual Abortion
- How many people
- Not given
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- Start not givento not given
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- Women only
- Adult
Study population: Endocrinology Outpatient Clinic
Who may be able to join
- non-pregnant women with euthyroid autoimmune thyroiditis and a history of first trimester recurrent spontaneous abortions
Who cannot join
- 1) presence of acute or chronic systemic diseases; 2) other autoimmune diseases; 3) pregnancy and lactation over the previous 6 months; 4) evidence of infectious diseases in the last 3 months; 5) treatment with drugs known to interfere with cytokine release, such as corticosteroids, immunosuppressors, or nonsteroidal antiinflammatory drugs, amiodarone, and lithium; 6) clinical history of hyperthyroidism and/or the presence of anti-TSH receptor antibodies.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Ankara Education and Research Hospital
Ankara, 06340
About this study
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
- Conditions
- Habitual Abortion
- Medical subject headings
- Abortion, Habitual
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| authoimmıne thyroiditis and habitual abortus | Not described | |
| authoimmune thyroiditis | Not described | |
| healthy controls | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Jul 2012 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Habitual AbortionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
Sponsor and investigators
- Lead sponsor
- Ankara Education and Research Hospital
- Sponsor type
- Other government
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01644318
- Sponsor's protocol ID
- 3848
- Status last verified
- Jul 2012
- First submitted
- 17 Jul 2012
- Last updated
- 19 Jul 2012
- Results posted
- No
Publications
Aktas A, Berberoglu Z, Fidan Y, Yazici AC, Koc G, Aral Y, Ademoglu E, Bekdemir H, Alphan Z. Higher levels of circulating CXCL-9 and CXCL-11 in euthyroid women with autoimmune thyroiditis and recurrent spontaneous abortions. Gynecol Endocrinol. 2014 Feb;30(2):157-60. doi: 10.3109/09513590.2013.871514. Epub 2013 Dec 19.
PubMed 24351073
Study at a glance
From the registry record, last updated by the sponsor on 19 Jul 2012. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions
- ClinicalTrials.gov ID
- NCT01644318
- Acronym / sponsor ID
- 3848
- Conditions
- Habitual Abortion
- Study type
- Observational
- Recruitment status
- Unknown status
- Lead sponsor
- Ankara Education and Research HospitalOther government
- First posted
- 19 Jul 2012 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| authoimmıne thyroiditis and habitual abortus | – | – |
| authoimmune thyroiditis | – | – |
| healthy controls | – | – |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- Female only
- Age groups
- Adult
- Study population
- Endocrinology Outpatient Clinic
Key inclusion criteria (1 listed)
- non-pregnant women with euthyroid autoimmune thyroiditis and a history of first trimester recurrent spontaneous abortions
Key exclusion criteria (1 listed)
- 1) presence of acute or chronic systemic diseases; 2) other autoimmune diseases; 3) pregnancy and lactation over the previous 6 months; 4) evidence of infectious diseases in the last 3 months; 5) treatment with drugs known to interfere with cytokine release, such as corticosteroids, immunosuppressors, or nonsteroidal antiinflammatory drugs, amiodarone, and lithium; 6) clinical history of hyperthyroidism and/or the presence of anti-TSH receptor antibodies.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Jul 2012.
- Derived from this study: PubMed 24351073Aktas A, Berberoglu Z, Fidan Y, Yazici AC, Koc G, Aral Y, Ademoglu E, Bekdemir H, Alphan Z. Higher levels of circulating CXCL-9 and CXCL-11 in euthyroid women with autoimmune thyroiditis and recurrent spontaneous abortions. Gynecol Endocrinol. 2014 Feb;30(2):157-60. doi: 10.3109/09513590.2013.871514. Epub 2013 Dec 19.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Habitual Abortion, run by Ankara Education and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 19 Jul 2012. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01644318, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Jul 2012.