Emotional IntelligenceEQNCT01721356
Neurobiological Basis of Emotional Intelligence
An observational study of Emotional Intelligence, run by Mclean Hospital.
Trial summary
Emotional Intelligence (EI) is defined as the ability to accurately perceive and identify emotions in oneself and others, understand and use emotions to enhance cognitive processes, and effectively manage one's own emotions as well as those of others. Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Emotional Intelligence
- How many people
- 70 participants
- Where
- No sites listed yet
- Study dates
- Sep 2009to May 2012
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Between 70 and 80 healthy, English speaking, right-handed, adults between the ages of 18 and 45 participated. Attempts were made to include equal numbers of men and women to permit the broadest generalization to the population and to permit direct assessment of gender effects, an issue that has received considerable attention recently regarding the neurobiology of affective processes. Subjects were not excluded on the basis of ethnicity, gender, or sexual orientation. Healthy participants were recruited via local advertisements, including email broadcasts such as the Harvard Hospital and Partners Healthcare systems, internet advertisements, and posting of IRB-approved flyers in various community centers. IRB-approved print advertisements were posted in local newspapers.
Who may be able to join
- Age range between 18 and 45
- Right handed
- Primary language must be English
Who cannot join
- Any history of neurological illness, current DSM-IV Axis I disorder, lifetime history of major depression or psychotic disorder, or head injury with loss of consciousness > 30 minutes
- Complicating medical conditions that may influence the outcome of neuropsychological assessment or functional imaging (e.g., HIV)
- Mixed or left-handedness
- Current score of 15 or greater on Beck Depression Inventory
- Abnormal visual acuity that is not corrected by contact lenses
- Metal within the body, claustrophobia, or other contraindications for neuroimaging
Show all 13Show fewer
- Less than 9th grade education
- Evidence of impaired reading comprehension
- Excess alcohol use (Males: regular intake of 5+ drinks on one occasion or >2 drinks per day on average for past 2 months; Females: 4+ drinks per day or >1 drink per day on average for past 2 months)
- History of alcoholism or substance use disorder
- Use of illicit drugs
- Best of 4 learning trials of Memory Suppression Task Training below 85%
- Indication of invalid responding, potentially including elevated Omission Rate, Inconsistency Index, or Positive/Negative Impression scales on EQi, or elevated Omission Rate or Scatter score on MSCEIT
About this study
Official title: The Neurobiological Basis and Potential Modification of Emotional Intelligence Through Affective / Behavioral Training
Emotional Intelligence (EI) is defined as the ability to accurately perceive and identify emotions in oneself and others, understand and use emotions to enhance cognitive processes, and effectively manage one's own emotions as well as those of others. Two major approaches to the construct of emotional intelligence have emerged. These two approaches can be broadly defined as the Trait and Ability Approaches. The Trait Approach, which is typically assessed via self-report measures such as that Bar-On Emotional Quotient Inventory, appears to be strongly related to existing models of personality and coping. The other major approach to EI follows an Ability Model, assuming that EI is similar to but distinct from other types of cognitive intelligence, and involves measurement of a variety of skills and abilities related to emotional processing. An understanding of the neurobiological substrate of emotional intelligence is beginning to emerge. One influential theory that is particularly relevant to the neurobiology of emotional intelligence is the "somatic marker hypothesis," yet there still remains a limited understanding of the neurobiological basis of EI. The proposed investigation will attempt to provide the most comprehensive study to date examining the behavioral, psychological, functional, and brain structural correlates of EI. The proposed study will use neuroimaging techniques to examine the relationship between current measures of EI, behavioral expression of emotionally competent capacities, brain functional responses, and structural cerebral organization.
The specific questions to be addressed and their associated hypotheses are:
- The two major approaches to EI (i.e., Trait vs. Ability) will show only modest, though significant positive correlations with one another.
- EI Trait measures will be highly correlated with measures of personality but weakly correlated with specific skills such as facial affect identification, emotional decision-making, and affectively based judgments, whereas EI Ability measures will correlate more highly with specific emotional skill measures.
- During functional MRI affective challenge tasks, EI scores will be negatively correlated with activity within the Somatic Marker Circuitry suggested by Damasio and colleagues (i.e., ventromedial prefrontal cortex, amygdala, insular cortex), as suggested by the neural efficiency hypothesis.
- Conditions
- Emotional Intelligence
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Healthy individuals | Healthy individuals ranging in age, race, ethnicity, socioeconomic status, and years of education |
What is being measured
The primary outcome is the main question the study is designed to answer.
Score on ability measure (MSCEIT) of emotional intelligence
Measured: Measure administered on the day of the MRI scan
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Nov 2012 (estimated)
- Study startSep 2009
- Primary completionMay 2012
- Study completionMay 2012
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Emotional IntelligenceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mclean Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, William Killgore, Mclean Hospital
- Investigators
- William D Killgore, PhD, Principal investigator, Mclean Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01721356
- Sponsor's protocol ID
- W81XWH-09-1-0730
- Acronym
- EQ
- Status last verified
- Nov 2012
- First submitted
- 31 Oct 2012
- Last updated
- 5 Nov 2012
- Results posted
- No
- Data monitoring committee
- No
Publications
Bajaj S, Raikes AC, Razi A, Miller MA, Killgore WD. Blue-Light Therapy Strengthens Resting-State Effective Connectivity within Default-Mode Network after Mild TBI. J Cent Nerv Syst Dis. 2021 May 19;13:11795735211015076. doi: 10.1177/11795735211015076. eCollection 2021.
PubMed 34104033
Study at a glance
From the registry record, last updated by the sponsor on 5 Nov 2012. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Neurobiological Basis and Potential Modification of Emotional Intelligence Through Affective / Behavioral Training
- ClinicalTrials.gov ID
- NCT01721356
- Acronym / sponsor ID
- EQ / W81XWH-09-1-0730
- Conditions
- Emotional Intelligence
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Mclean HospitalUniversity, hospital or other
- Study start
- Sep 2009
- Primary completion
- May 2012 (actual)
- Study completion
- May 2012 (actual)
- First posted
- 5 Nov 2012 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Emotional Intelligence (EI) is defined as the ability to accurately perceive and identify emotions in oneself and others, understand and use emotions to enhance cognitive processes, and effectively manage one's own emotions as well as those of others. Two major approaches to the construct of emotional intelligence have emerged. These two approaches can be broadly defined as the Trait and Ability Approaches. The Trait Approach, which is typically assessed via self-report measures such as that Bar-On Emotional Quotient Inventory, appears to be strongly related to existing models of personality and coping. The other major approach to EI follows an Ability Model, assuming that EI is similar to but distinct from other types of cognitive intelligence, and involves measurement of a variety of skills and abilities related to emotional processing. An understanding of the neurobiological substrate of emotional intelligence is beginning to emerge. One influential theory that is particularly relevant to the neurobiology of emotional intelligence is the "somatic marker hypothesis," yet there still remains a limited understanding of the neurobiological basis of EI. The proposed investigation will attempt to provide the most comprehensive study to date examining the behavioral, psychological, functional, and brain structural correlates of EI. The proposed study will use neuroimaging techniques to examine the relationship between current measures of EI, behavioral expression of emotionally competent capacities, brain functional responses, and structural cerebral organization.
The specific questions to be addressed and their associated hypotheses are:
- The two major approaches to EI (i.e., Trait vs. Ability) will show only modest, though significant positive correlations with one another.
- EI Trait measures will be highly correlated with measures of personality but weakly correlated with specific skills such as facial affect identification, emotional decision-making, and affectively based judgments, whereas EI Ability measures will correlate more highly with specific emotional skill measures.
- During functional MRI affective challenge tasks, EI scores will be negatively correlated with activity within the Somatic Marker Circuitry suggested by Damasio and colleagues (i.e., ventromedial prefrontal cortex, amygdala, insular cortex), as suggested by the neural efficiency hypothesis.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Healthy individuals | – | –Healthy individuals ranging in age, race, ethnicity, socioeconomic status, and years of education |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Between 70 and 80 healthy, English speaking, right-handed, adults between the ages of 18 and 45 participated. Attempts were made to include equal numbers of men and women to permit the broadest generalization to the population and to permit direct assessment of gender effects, an issue that has received considerable attention recently regarding the neurobiology of affective processes. Subjects were not excluded on the basis of ethnicity, gender, or sexual orientation. Healthy participants were recruited via local advertisements, including email broadcasts such as the Harvard Hospital and Partners Healthcare systems, internet advertisements, and posting of IRB-approved flyers in various community centers. IRB-approved print advertisements were posted in local newspapers.
Key inclusion criteria (3 listed)
- Age range between 18 and 45
- Right handed
- Primary language must be English
Key exclusion criteria (13 listed)
- Any history of neurological illness, current DSM-IV Axis I disorder, lifetime history of major depression or psychotic disorder, or head injury with loss of consciousness > 30 minutes
- Complicating medical conditions that may influence the outcome of neuropsychological assessment or functional imaging (e.g., HIV)
- Mixed or left-handedness
- Current score of 15 or greater on Beck Depression Inventory
- Abnormal visual acuity that is not corrected by contact lenses
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Score on ability measure (MSCEIT) of emotional intelligence
Time frame: Measure administered on the day of the MRI scan
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Nov 2012.
- Derived from this study: PubMed 34104033Bajaj S, Raikes AC, Razi A, Miller MA, Killgore WD. Blue-Light Therapy Strengthens Resting-State Effective Connectivity within Default-Mode Network after Mild TBI. J Cent Nerv Syst Dis. 2021 May 19;13:11795735211015076. doi: 10.1177/11795735211015076. eCollection 2021.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
William D Killgore, PhD principal investigator
Mclean Hospital
Questions about this trial
What is this clinical trial studying?
An observational study of Emotional Intelligence, run by Mclean Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Nov 2012. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Score on ability measure (MSCEIT) of emotional intelligence (time frame: Measure administered on the day of the MRI scan). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01721356, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Nov 2012.