Use and Dissemination of Smoking Cessation InterventionNCT01746472
Study of the Diffusion of a Smoking Cessation Application Through an Online Network
A study testing Facebook app - condition t, Facebook app - condition z and Facebook app - condition B-active in people with Use and Dissemination of Smoking Cessation Intervention and Cessation of Smoking, run by Truth Initiative at 1 site in United States.
Trial summary
Effective evidence-based interventions exist for smoking cessation delivered over the Internet, but consumer acceptance and adherence remains low. Scalable and efficient mechanisms to disseminate these interventions online are needed, and existing online social networks provide a potential mechanism. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Use and Dissemination of Smoking Cessation Intervention, Cessation of Smoking
- What is being tested?
- Facebook app - condition t, Facebook app - condition z and Facebook app - condition B-active
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 11,413 participants
- Where
- 1 siteUnited States
- Study dates
- Dec 2012to Oct 2014
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Facebook user
- Age 18 years or older
- Entered UbiQUITous Facebook Application
- Confirms smoker status
- U.S. resident
Who cannot join
- Non-smoker
- Under 18 years old
- Non-U.S. resident
- Non-Facebook advertisement point of entry
Trial locations and contacts
1 site in 1 country.
United States1 site
Truth Initiative
Washington D.C., District of Columbia, 20001
About this study
Official title: Online Social Networks for Dissemination of Smoking Cessation Interventions
Effective evidence-based interventions exist for smoking cessation delivered over the Internet, but consumer acceptance and adherence remains low. Scalable and efficient mechanisms to disseminate these interventions online are needed, and existing online social networks provide a potential mechanism. This is a proposal for a randomized, factorial trial of the dissemination of an evidence-based intervention through the massive Facebook social network, with the goal of determining intervention characteristics that drive viral spread.
- Being tested
- Facebook app - condition t, Facebook app - condition z, Facebook app - condition B-active, Facebook app - condition B-passive
- Medical subject headings
- Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Facebook app - condition tBehavioural
Application components hypothesized to increase the duration (t, time) that a participant spends using the application.
Facebook app - condition zBehavioural
Application components hypothesized to increase the number of friends that a user has that are eligible to install the application.
Facebook app - condition B-activeBehavioural
Also called Ba
Application components hypothesized to increase the contagiousness of the app by increasing a users ability and desire to proactively contact others.
Facebook app - condition B-passiveBehavioural
Also called Bp
Application components hypothesized to increase the contagiousness of the app by increasing the passive diffusion of information from the user to their friends.
| Study group | Role | What they receive |
|---|---|---|
| 2 - B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition B-passive |
| 3 - B-active | Experimental | Not described Receives: Behavioral: Facebook app - condition B-active |
| 4 - B-active, B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition B-active; Behavioral: Facebook app - condition B-passive |
| 6 - z, B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition z; Behavioral: Facebook app - condition B-passive |
| 7 - z, B-active | Experimental | Not described Receives: Behavioral: Facebook app - condition z; Behavioral: Facebook app - condition B-active |
| 8 - z, B-active, B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition z; Behavioral: Facebook app - condition B-active; Behavioral: Facebook app - condition B-passive |
| 10 - t, B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition t; Behavioral: Facebook app - condition B-passive |
| 11 - t, B-active | Experimental | Not described Receives: Behavioral: Facebook app - condition t; Behavioral: Facebook app - condition B-active |
| 12 - t, B-active, B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition t; Behavioral: Facebook app - condition B-active; Behavioral: Facebook app - condition B-passive |
| 14 - t, z | Experimental | Not described Receives: Behavioral: Facebook app - condition t; Behavioral: Facebook app - condition z |
| 15 - t, z, B-active | Experimental | Not described Receives: Behavioral: Facebook app - condition t; Behavioral: Facebook app - condition z; Behavioral: Facebook app - condition B-active |
| 16 - t, z, B-active, B-passive | Experimental | Not described Receives: Behavioral: Facebook app - condition t; Behavioral: Facebook app - condition z; Behavioral: Facebook app - condition B-active; Behavioral: Facebook app - condition B-passive |
What is being measured
The primary outcome is the main question the study is designed to answer.
Reproductive rate
The investigators will measure the reproductive rate for each condition, in other words the average number of additional individuals that install the application for each original individual recruited to participate. Higher reproductive rates indicate more efficient and faster dissemination.
Measured: 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Dec 2012 (estimated)
- Study startDec 2012
- Primary completionOct 2013
- Study completionOct 2014
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Use and Dissemination of Smoking Cessation InterventionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 11,413 participants (actual)
Sponsor and investigators
- Lead sponsor
- Truth Initiative
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Amanda L Graham, PhD, Principal investigator, Truth Initiative
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01746472
- Sponsor's protocol ID
- 1R01CA155369-01A1
- Status last verified
- Mar 2015
- First submitted
- 3 Dec 2012
- Last updated
- 15 Mar 2016
- Results posted
- No
- Data monitoring committee
- Yes
Publications
Cobb NK, Jacobs MA, Saul J, Wileyto EP, Graham AL. Diffusion of an evidence-based smoking cessation intervention through Facebook: a randomised controlled trial study protocol. BMJ Open. 2014 Jan 21;4(1):e004089. doi: 10.1136/bmjopen-2013-004089.
PubMed 24448847
Study at a glance
From the registry record, last updated by the sponsor on 15 Mar 2016. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Online Social Networks for Dissemination of Smoking Cessation Interventions
- ClinicalTrials.gov ID
- NCT01746472
- Acronym / sponsor ID
- 1R01CA155369-01A1
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 11,413 participants (actual)
- Lead sponsor
- Truth InitiativeUniversity, hospital or other
- Study start
- Dec 2012
- Primary completion
- Oct 2013 (actual)
- Study completion
- Oct 2014 (actual)
- First posted
- 11 Dec 2012 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Effective evidence-based interventions exist for smoking cessation delivered over the Internet, but consumer acceptance and adherence remains low. Scalable and efficient mechanisms to disseminate these interventions online are needed, and existing online social networks provide a potential mechanism. This is a proposal for a randomized, factorial trial of the dissemination of an evidence-based intervention through the massive Facebook social network, with the goal of determining intervention characteristics that drive viral spread.
Study design
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Double blind (participant, investigator)
- Number of arms
- 12
| Arm | Type | Receives |
|---|---|---|
| 2 - B-passive | Experimental | Behavioral: Facebook app - condition B-passive |
| 3 - B-active | Experimental | Behavioral: Facebook app - condition B-active |
| 4 - B-active, B-passive | Experimental | Behavioral: Facebook app - condition B-active, Behavioral: Facebook app - condition B-passive |
| 6 - z, B-passive | Experimental | Behavioral: Facebook app - condition z, Behavioral: Facebook app - condition B-passive |
| 7 - z, B-active | Experimental | Behavioral: Facebook app - condition z, Behavioral: Facebook app - condition B-active |
| 8 - z, B-active, B-passive | Experimental | Behavioral: Facebook app - condition z, Behavioral: Facebook app - condition B-active, Behavioral: Facebook app - condition B-passive |
| 10 - t, B-passive | Experimental | Behavioral: Facebook app - condition t, Behavioral: Facebook app - condition B-passive |
| 11 - t, B-active | Experimental | Behavioral: Facebook app - condition t, Behavioral: Facebook app - condition B-active |
| 12 - t, B-active, B-passive | Experimental | Behavioral: Facebook app - condition t, Behavioral: Facebook app - condition B-active, Behavioral: Facebook app - condition B-passive |
| 14 - t, z | Experimental | Behavioral: Facebook app - condition t, Behavioral: Facebook app - condition z |
| 15 - t, z, B-active | Experimental | Behavioral: Facebook app - condition t, Behavioral: Facebook app - condition z, Behavioral: Facebook app - condition B-active |
| 16 - t, z, B-active, B-passive | Experimental | Behavioral: Facebook app - condition t, Behavioral: Facebook app - condition z, Behavioral: Facebook app - condition B-active, Behavioral: Facebook app - condition B-passive |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Facebook user
- Age 18 years or older
- Entered UbiQUITous Facebook Application
- Confirms smoker status
- U.S. resident
Key exclusion criteria (4 listed)
- Non-smoker
- Under 18 years old
- Non-U.S. resident
- Non-Facebook advertisement point of entry
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Facebook app - condition tApplication components hypothesized to increase the duration (t, time) that a participant spends using the application. | Behavioural | 10 - t, B-passive, 11 - t, B-active, 12 - t, B-active, B-passive, 14 - t, z, 15 - t, z, B-active, 16 - t, z, B-active, B-passive |
| Facebook app - condition zApplication components hypothesized to increase the number of friends that a user has that are eligible to install the application. | Behavioural | 14 - t, z, 15 - t, z, B-active, 16 - t, z, B-active, B-passive, 6 - z, B-passive, 7 - z, B-active, 8 - z, B-active, B-passive |
| Facebook app - condition B-activeAlso: BaApplication components hypothesized to increase the contagiousness of the app by increasing a users ability and desire to proactively contact others. | Behavioural | 11 - t, B-active, 12 - t, B-active, B-passive, 15 - t, z, B-active, 16 - t, z, B-active, B-passive, 3 - B-active, 4 - B-active, B-passive, 7 - z, B-active, 8 - z, B-active, B-passive |
| Facebook app - condition B-passiveAlso: BpApplication components hypothesized to increase the contagiousness of the app by increasing the passive diffusion of information from the user to their friends. | Behavioural | 10 - t, B-passive, 12 - t, B-active, B-passive, 16 - t, z, B-active, B-passive, 2 - B-passive, 4 - B-active, B-passive, 6 - z, B-passive, 8 - z, B-active, B-passive |
Primary outcome
Reproductive rate
Time frame: 30 days
The investigators will measure the reproductive rate for each condition, in other words the average number of additional individuals that install the application for each original individual recruited to participate. Higher reproductive rates indicate more efficient and faster dissemination.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Mar 2016.
- Derived from this study: PubMed 24448847Cobb NK, Jacobs MA, Saul J, Wileyto EP, Graham AL. Diffusion of an evidence-based smoking cessation intervention through Facebook: a randomised controlled trial study protocol. BMJ Open. 2014 Jan 21;4(1):e004089. doi: 10.1136/bmjopen-2013-004089.
- UbiQUITous Facebook Application (Intervention)Link provided by the sponsor.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Amanda L Graham, PhD principal investigator
Truth Initiative
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Facebook app - condition t, Facebook app - condition z and Facebook app - condition B-active in people with Use and Dissemination of Smoking Cessation Intervention and Cessation of Smoking, run by Truth Initiative at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Mar 2016. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Reproductive rate (time frame: 30 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01746472, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Mar 2016.