Critical Care, Fluid ResuscitationFluid-TRIPSNCT02002013
The Fluid Translation of Research Into Practice Study
An observational study of Critical Care, Fluid Resuscitation, run by The George Institute for Global Health, Australia at 1 site in Australia.
Trial summary
Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs Read more about this study
- Who is it for?
- Ages 16 years and olderHealthy volunteers can take part
- Conditions the study is for
- Critical Care, Fluid Resuscitation
- How many people
- 2,000 participants
- Where
- 1 siteAustralia
- Study dates
- Apr 2014to Dec 2014
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Adult patients present in the ICU on the study day
Who may be able to join
- Adult patients present in the ICU on the study day or admitted during the 24-hour study period will be included in the study sample.
Who cannot join
- Children under 16 years are excluded
Trial locations and contacts
1 site in 1 country.
Australia1 site
The The George Institute for global health; Critical Care & Trauma Division
Sydney, New South Wales, 2000
About this study
Official title: The Fluid Translation of Research Into Practice Study (Fluid-TRIPS): An International Cross-Sectional Survey of Fluid Resuscitation Practice
Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs
Read the detailed description
The Fluid-Translation of Research into Practice Study (TRIPS) is an international, single day, cross-sectional study planned for the second quarter of 2014, coordinated by the George Institute for Global Health, with the purpose of documenting prescribing practices for fluid resuscitation in intensive care units (ICUs) worldwide. This international cross-sectional study follows on from the publication of large-scale randomized controlled trials and meta-analyses of fluid resuscitation, which provide evidence of how fluid resuscitation may affect patient-centered outcomes.
Fluid-TRIPS is a repeat of the Saline versus Albumin for Fluid Evaluation (SAFE)-TRIPS which was an international cross-sectional survey conducted in 2007 that had 391 ICU's participate from 25 countries and provided insight into international fluid resuscitation practice at that time. Along with establishing if fluid resuscitation practices have changed since SAFE-TRIPS, Fluid-TRIPS also aims to determine the relationship between fluid choice and evidence, along with understand other factors that may influence the choice of bolus fluid in clinical practice.
- Conditions
- Critical Care, Fluid Resuscitation
- Keywords
- Adult, ICU patient, Fluid resuscitation, observational study
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Adult ICU patient receiving Fluid resus | Adult patients present in the ICU at the start of the study day or admitted during the 24-hour study period will be included in the study sample. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Type of resuscitation fluid in ICU
To describe the amount and type of resuscitation fluid currently administered to adult patients in intensive care units (ICU) in different countries
Measured: 24-hour study day
Secondary outcomes (1)
Cost comparison of fluid choice between regions
To describe and compare the costs of fluid choice between different geographical regions
Measured: Designated 24-hour study day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Dec 2013 (estimated)
- Study startApr 2014
- Primary completionDec 2014
- Study completionDec 2014
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Critical Care, Fluid ResuscitationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 2,000 participants (actual)
Sponsor and investigators
- Lead sponsor
- The George Institute for Global Health, Australia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Naomi Hammond, The George Institute for Global Health, Australia
- Investigators
- Naomi Hammond, Study chair, The George InstituteColman Taylor, Study chair, The George Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02002013
- Sponsor's protocol ID
- GI-CCT300413
- Other IDs
- ACTRN12613001172796
- Acronym
- Fluid-TRIPS
- Status last verified
- Mar 2015
- First submitted
- 28 Nov 2013
- Last updated
- 11 Mar 2015
- Results posted
- No
- Data monitoring committee
- No
Publications
Hammond NE, Taylor C, Finfer S, Machado FR, An Y, Billot L, Bloos F, Bozza F, Cavalcanti AB, Correa M, Du B, Hjortrup PB, Li Y, McIntryre L, Saxena M, Schortgen F, Watts NR, Myburgh J; Fluid-TRIPS and Fluidos Investigators; George Institute for Global Health, The ANZICS Clinical Trials Group, BRICNet, and the REVA research Network. Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study. PLoS One. 2017 May 12;12(5):e0176292. doi: 10.1371/journal.pone.0176292. eCollection 2017.
PubMed 28498856
Study at a glance
From the registry record, last updated by the sponsor on 11 Mar 2015. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Fluid Translation of Research Into Practice Study (Fluid-TRIPS): An International Cross-Sectional Survey of Fluid Resuscitation Practice
- ClinicalTrials.gov ID
- NCT02002013
- Acronym / sponsor ID
- Fluid-TRIPS / GI-CCT300413
- Conditions
- Critical Care, Fluid Resuscitation
- Keywords
- Adult, ICU patient, Fluid resuscitation, observational study
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 2,000 participants (actual)
- Lead sponsor
- The George Institute for Global Health, AustraliaUniversity, hospital or other
- Study start
- Apr 2014
- Primary completion
- Dec 2014 (actual)
- Study completion
- Dec 2014 (actual)
- First posted
- 5 Dec 2013 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs
Detailed description
The Fluid-Translation of Research into Practice Study (TRIPS) is an international, single day, cross-sectional study planned for the second quarter of 2014, coordinated by the George Institute for Global Health, with the purpose of documenting prescribing practices for fluid resuscitation in intensive care units (ICUs) worldwide. This international cross-sectional study follows on from the publication of large-scale randomized controlled trials and meta-analyses of fluid resuscitation, which provide evidence of how fluid resuscitation may affect patient-centered outcomes.
Fluid-TRIPS is a repeat of the Saline versus Albumin for Fluid Evaluation (SAFE)-TRIPS which was an international cross-sectional survey conducted in 2007 that had 391 ICU's participate from 25 countries and provided insight into international fluid resuscitation practice at that time. Along with establishing if fluid resuscitation practices have changed since SAFE-TRIPS, Fluid-TRIPS also aims to determine the relationship between fluid choice and evidence, along with understand other factors that may influence the choice of bolus fluid in clinical practice.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Adult ICU patient receiving Fluid resus | – | –Adult patients present in the ICU at the start of the study day or admitted during the 24-hour study period will be included in the study sample. |
Who may qualify
- Ages
- 16 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Adult patients present in the ICU on the study day
Key inclusion criteria (1 listed)
- Adult patients present in the ICU on the study day or admitted during the 24-hour study period will be included in the study sample.
Key exclusion criteria (1 listed)
- Children under 16 years are excluded
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Type of resuscitation fluid in ICU
Time frame: 24-hour study day
To describe the amount and type of resuscitation fluid currently administered to adult patients in intensive care units (ICU) in different countries
1 secondary outcome
Cost comparison of fluid choice between regions
Time frame: Designated 24-hour study day
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Mar 2015.
- Derived from this study: PubMed 28498856Hammond NE, Taylor C, Finfer S, Machado FR, An Y, Billot L, Bloos F, Bozza F, Cavalcanti AB, Correa M, Du B, Hjortrup PB, Li Y, McIntryre L, Saxena M, Schortgen F, Watts NR, Myburgh J; Fluid-TRIPS and Fluidos Investigators; George Institute for Global Health, The ANZICS Clinical Trials Group, BRICNet, and the REVA research Network. Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study. PLoS One. 2017 May 12;12(5):e0176292. doi: 10.1371/journal.pone.0176292. eCollection 2017.
Related trials for Critical Care, Fluid Resuscitation
Not yet recruitingObservational study
Intravenous Fluid Practices in Turkish Intensive Care Units (TR-FLUID)
Critical Illness, Fluid Therapy
Recruiting
Effect of Giving Reduced Fluid in Children After Trauma
Critical Illness, Pediatrics
RecruitingPhase 3
Early Vasopressors in Sepsis
Sepsis
Recruiting
Fluid Management and Individualized Resuscitation in Sepsis
Sepsis, Shock
Not yet recruitingPhase 3
Human Albumin for Resuscitation in Surgical Septic Shock: A Randomized Controlled Trial (ALBUS Study)
Critical Illness, Septic Shock
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Naomi Hammond study chair
The George Institute
Colman Taylor study chair
The George Institute
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Critical Care, Fluid Resuscitation, run by The George Institute for Global Health, Australia at 1 site in Australia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Mar 2015. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Australia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Type of resuscitation fluid in ICU (time frame: 24-hour study day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02002013, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Mar 2015.